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Hey guys, I'm back with another video! This time, we will cover the basics of cannabinoids. We'll discuss the history, biochemistry, pharmacology and total synthesis of these highly useful natural products. Recent research is used as an example of the importance and potential of cannabinoids in medicine. https://www.instagram.com/totalsynthesis_official/ https://www.patreon.com/totalsynthesis https://www.total-synthesis.com This video does not endorse the preparation of illegal substances. No detailed steps or procedures for syntheses of illegal drugs are discussed. I hope it's clear that here we focus on fascinating aspects of science and on the potential that compounds have in improving the lives of patients. 00:00 Introduction of medical cannabinoids; Applications of cannabidiol (CBD) and tetrahydrocannabinol (THC) for treatment of epilepsy and other conditions; Introduction of legal high of liverwort 04:35 History and Isolation of THC; Discovery of the endocannabinoid system, endocannabinoid receptors (CB1 and CB2) and endocannabinoids anandamide and arachidonylglyceride; CB1 antagonists as anti-obesity drugs; Total synthesis of THC and CBD by Raphael Mechoulam at the Weizmann Institute 15:18 Can you get legally high from moss or liverwort? Summary of pharmacological results from the key paper, based on work of Professor Gertsch and co-workers at the University of Bern; Tetrad test, Prostaglandins; Implications for medicinal applications 21:32 Organic synthesis and two total syntheses of cis-perrottetine by Professor Carreira at ETH Zürich (2018) and Professor Kim at Seoul University (2008); Discussion of key steps and synthetic strategies and reaction mechanisms 28:17 Closing remarks Mechoulam interview/documentary: - The Scientist (2015): https://www.youtube.com/watch?v=fu6FhJIyTEc Liverwort paper: - Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high (Science Advances 2018, 4, 2166): http://advances.sciencemag.org/content/4/10/eaat2166 Some recommended books on organic synthesis: - Clayden, Greeves, Warren; Organic Chemistry (basic organic chemistry knowledge) - Wyatt, Warren; Organic Synthesis: The Disconnection Approach (excellent introduction to retrosynthesis) - Kurti, Czako; Strategic Applications of Named Reactions in Organic Synthesis (extensive toolkit of reactions and applications thereof with common conditions) - Nicolaou et al; Classics in Total Synthesis 1-3 (the ultimate total synthesis trilogy) - Nicolaou; Molecules That Changed the World (the world's most important molecules and their impact on everyday life) - Carreira, Kvaerno; Classics in Stereoselective Synthesis (compilation of the groundbreaking methods of stereoselective synthesis and application to synthesis of stereochemically complex structures)

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Tinnitus is a common condition that affects millions of people worldwide. It is characterized by ringing, buzzing, or humming in the ears, which can be constant or intermittent. While the exact cause of tinnitus is not always clear, it is often associated with underlying health conditions, exposure to loud noises, or even stress and anxiety. Living with tinnitus can be challenging, as the constant noise can be distracting and disruptive to everyday life. Fortunately, there are various treatment options available to help manage and alleviate tinnitus symptoms, including the use of CBD gummies.

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Another essential factor to consider when choosing CBD gummies for tinnitus relief is the CBD content per serving. While there is no standard dosage for CBD, it’s important to start with a low dose and gradually increase until you find the level that works best for you. Some CBD gummies come in varying strengths, so choose a product that allows for easy dose adjustment to tailor to your specific needs.

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In addition to taking CBD gummies regularly, it’s also essential to adopt other healthy habits that can complement the effects of CBD on tinnitus relief. Practices such as stress management techniques, adequate sleep, regular exercise, and a balanced diet can all contribute to overall wellness and support the benefits of CBD in alleviating tinnitus symptoms.

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Conclusion

In conclusion, CBD gummies offer a convenient and enjoyable way to incorporate CBD into your tinnitus relief routine. With their potential anti-inflammatory, analgesic, and relaxant effects, CBD gummies can help manage tinnitus symptoms and improve your overall quality of life. When choosing CBD gummies for tinnitus relief, prioritize quality, potency, and consistency to ensure you are getting a safe and effective product. By incorporating CBD gummies into your daily wellness routine, you can tune out tinnitus and experience relief from the constant buzzing or ringing in your ears.

FAQ: Can CBD gummies cure tinnitus?

While CBD gummies may help manage and alleviate tinnitus symptoms, there is currently no cure for tinnitus. CBD can offer relief by reducing inflammation, improving blood flow, and promoting relaxation in the auditory system. However, individual responses to CBD may vary, so it’s essential to consult with a healthcare provider before starting any new treatment regimen.

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