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Are CBD and THC as effective as people believe — or is it mostly placebo? In this episode, we break down the latest clinical evidence on medical cannabis, exploring the real-world impact of CBD, THC, and cannabis-based therapies across conditions like cancer, chronic pain, anxiety, epilepsy, and more. With medical use on the rise globally, it’s time to separate hype from hard data. 🔍 We explore: - What randomized trials and meta-analyses actually say about effectiveness - Differences between THC and CBD in clinical use - Side effects, tolerability, and potential cognitive risks - How cannabinoids affect the brain, body, and mental health 📄 Scientific References: -Castle, R. D., Marzolf, J., Morris, M., & Bushell, W. C. (2025). Meta-analysis of medical cannabis outcomes and associations with cancer. Frontiers in Oncology, 15, 1490621. https://doi.org/10.3389/fonc.2025.1490621 - Sultan, S. R., Millar, S. A., England, T. J., & O’Sullivan, S. E. (2017). A systematic review and meta-analysis of the haemodynamic effects of cannabidiol. Frontiers in Pharmacology, 8, 81. https://doi.org/10.3389/fphar.2017.00081 - Batalla, A., Bos, J., Postma, A., & Bossong, M. G. (2021). The impact of cannabidiol on human brain function: A systematic review. Frontiers in Pharmacology, 11, 618184. https://doi.org/10.3389/fphar.2020.618184 - Leen, N. A., Kowal, M. A., Batalla, A., & Bossong, M. G. (2024). The effects of standardized cannabis products in healthy volunteers and patients: A systematic literature review. Frontiers in Pharmacology, 15, 1411631. https://doi.org/10.3389/fphar.2024.1411631 - Pagano, C., Navarra, G., Coppola, L., Avilia, G., Bifulco, M., & Laezza, C. (2022). Cannabinoids: Therapeutic use in clinical practice. International Journal of Molecular Sciences, 23(6), 3344. https://doi.org/10.3390/ijms23063344 - Pintori, N., Caria, F., De Luca, M. A., & Miliano, C. (2023). THC and CBD: Villain versus hero? Insights into adolescent exposure. International Journal of Molecular Sciences, 24(6), 5251. https://doi.org/10.3390/ijms24065251 - Borgan, F., Beck, K., Butler, E., McCutcheon, R., Veronese, M., Vernon, A., & Howes, O. D. (2019). The effects of cannabinoid 1 receptor compounds on memory: A meta-analysis and systematic review across species. Psychopharmacology. https://doi.org/10.1007/s00213-019-05283-3 - Stasiak, S. P., Hall, S. H., Nichols, J., Yaacoub, I., & Shelley, T. C. S. (2021). Examining the effects of cannabidiol (CBD) on anxiety and heart rate variability during acute stress: A randomized placebo-controlled trial. Psychopharmacology, 238(7), 1965–1977. https://doi.org/10.1007/s00213-021-05823-w - Lees, R., Hines, L. A., Hindocha, C., et al. (2023). Effect of four-week cannabidiol treatment on cognitive function: Secondary outcomes from a randomized clinical trial for cannabis use disorder. Psychopharmacology, 240(2), 337–346. https://doi.org/10.1007/s00213-022-06303-5 - Hoch, E., Hall, W., Friemel, C., et al. (2024). The risks and benefits of cannabis: A review of reviews. European Archives of Psychiatry and Clinical Neuroscience. https://doi.org/10.1007/s00406-024-01880-2 - Sarris, J., Sinclair, J., Karamacoska, D., Davidson, M., & Firth, J. (2020). Medicinal cannabis for psychiatric disorders: A clinically-focused systematic review. BMC Psychiatry, 20, 24. https://doi.org/10.1186/s12888-019-2409-8 - Bilbao, A., & Spanagel, R. (2022). Medical cannabinoids: A pharmacology-based systematic review and meta-analysis for all relevant medical indications. BMC Medicine, 20, 259. https://doi.org/10.1186/s12916-022-02459-1 - Lo, L. A., Lo, C. A., Pereira, C., et al. (2024). The acute effects of cannabidiol on cognitive and psychomotor performance: A systematic review and meta-analysis of human laboratory studies. Psychopharmacology. https://doi.org/10.1038/s41386-024-01847-w - Velayudhan, L., McGoohan, K., & Bhattacharyya, S. (2021). Evaluation of THC-related neuropsychiatric symptoms among adults aged 50 years and older: A systematic review and meta-regression analysis. JAMA Network Open, 4(2), e2035913. https://doi.org/10.1001/jamanetworkopen.2020.35913 🎧 Whether you're a clinician, patient, or just curious about cannabis, this episode brings nuanced, evidence-based insights to a frequently polarized topic. ⚠️ Disclaimer: This podcast summarizes peer-reviewed scientific research for informational and educational purposes only. It does not constitute medical advice. Always consult a licensed healthcare provider before starting or changing any medication, supplement, or treatment approach. 💡 Note: Content created with support from Google’s NotebookLM. The views expressed are those of the host and do not represent the original authors or their institutions. 🔔 Don’t forget to like, subscribe, and share if you find this episode helpful! #CBD #THC #MedicalCannabis #CannabisScience #ClinicalResearch #HealthFacts #EvidenceBased #SciencePodcast

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Cannabis, Gras, Weed, Hanf, Marihuana und Haschisch! Alles gleich und doch irgendwie anders? Was das alles ist, wie es in unserem Körper wirkt und was das mit THC (Tetrahydrocannabinol) zu tun hat, erfährst Du in diesem Video! Hier nochmal die Fragen die ich gerne mit Dir diskutieren möchte: - Cannabiskonsum: Hast Du schonmal gekifft? - Bist Du für oder gegen eine Legalisierung von Cannabis? - Wie hoch sollt der Eigenbedarf sein? - Verhindert man mit einer Legalisierung die Kriminalität oder die Verunreinigung von Cannabis? - Wie findest Du es, dass man sich in Deutschland Cannabis vom Arzt verschreiben lassen kann? - Cannabisabhängigkeit: Macht der regelmäßige Konsum von Marihuana abhängig? Wenn Dir das Video gefallen hat, dann gib einen Daumen hoch und abonnier kostenlos den YouTube-Kanal! Schreib mir unten in die Kommentare ob Du noch mehr über das Thema wissen willst oder welche Themen Dich sonst noch interessieren! Wenn Du mir helfen willst, meine Videos zu übersetzen dann klickt hier: https://goo.gl/cMhxSC Hier kannst Du Dich für die Medizinstudium Examen Kurse von MEDI LEARN eintragen, die mir sehr geholfen haben: https://goo.gl/9fDqEm Auf Klausuren lerne ich mit Lecturio: http://lectur.io/5x Viel Spaß! Dein Doc Mo ------------------------------------------------------------------------------------------------------------ Vielen Dank an Steve Heng und die Creative Forge für die Unterstützung! Creative Forge: https://goo.gl/KQv9Vt ------------------------------------------------------------------------------------------------------------ Folgt mir auch auf meinen anderen Social Media Kanälen :) YouTube: http://www.youtube.com/teamdocmo Instagram: http://www.instagram.com/doc__mo Facebook: http://www.facebook.com/teamdocmo DocCheck: http://www.doccheck.com/de/profiles/8... Twitter: http://www.twitter.com/teamdocmo Tik Tok: teamdocmo

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CBD oil has gained a lot of popularity in recent years for its potential health benefits. Derived from the cannabis plant, CBD oil is a natural remedy that can help with various ailments such as anxiety, chronic pain, inflammation, and more. However, for beginners, navigating the world of CBD oil can be overwhelming. From different types of products to dosages and methods of consumption, there is a lot to learn before you start incorporating CBD oil into your daily routine. This article will guide you through the basics of CBD oil and how to take it as a beginner.

Types of CBD Products

When it comes to CBD products, there are various options to choose from. The most common types include CBD oil tinctures, capsules, edibles, topicals, and vapes. CBD oil tinctures are one of the most popular choices as they are easy to use and can be absorbed quickly by placing a few drops under your tongue. Capsules are another convenient option for those who prefer a pre-measured dosage. Edibles, such as gummies or chocolates, offer a tasty way to consume CBD. Topicals are applied directly to the skin and are great for targeting specific areas of pain or inflammation. Vapes provide a fast-acting method of consumption through inhalation.

Choosing the Right Dosage

One of the most common questions new CBD users have is, “How much CBD should I take?” The answer to this question depends on various factors, including your weight, metabolism, the severity of your symptoms, and the type of product you are using. It is important to start with a low dosage and gradually increase it until you find the right amount that works for you. A general guideline is to start with 10-20mg of CBD per day and increase the dosage by 5-10mg every week until you experience the desired effects.

Methods of Consumption

There are several ways to consume CBD oil, each offering different benefits and effects. Sublingual consumption, where you place the oil under your tongue and hold it there for a minute before swallowing, allows for quick absorption into the bloodstream. Ingesting CBD oil through capsules or edibles takes longer to take effect but provides longer-lasting relief. Topical application is ideal for localized pain or inflammation, as the CBD is absorbed directly through the skin. Vaping CBD oil is the fastest-acting method, as it enters the bloodstream through the lungs.Lofi Cbd Gummies Review Does Gummy Bears Works

Timing and Frequency

When it comes to taking CBD oil, timing and frequency are essential factors to consider. It is recommended to take CBD oil at the same time each day to maintain consistency and allow your body to adjust to the supplement. Some people prefer to take CBD oil in the morning to kickstart their day, while others find it more beneficial to take it in the evening for relaxation and better sleep. The frequency of dosing depends on your individual needs and the severity of your symptoms. Remember to start low and go slow when finding the right dosage and timing for you.

Potential Side Effects

While CBD oil is generally well-tolerated by most people, there are some potential side effects to be aware of. The most common side effects include dry mouth, drowsiness, changes in appetite, and diarrhea. These side effects are typically mild and go away on their own after a few days. However, if you experience any severe side effects or allergic reactions, it is essential to stop taking CBD oil and consult with a healthcare professional. It is also important to note that CBD may interact with certain medications, so it is recommended to talk to your doctor before incorporating CBD oil into your daily routine.

In summary, CBD oil is a natural remedy that can offer numerous health benefits for beginners. By understanding the different types of products, choosing the right dosage, exploring various methods of consumption, considering timing and frequency, and being aware of potential side effects, you can start incorporating CBD oil into your daily routine with confidence. Remember to start low and go slow, listen to your body, and consult with a healthcare professional if needed.

FAQ:

1. Is CBD oil legal?

Yes, CBD oil derived from hemp with less than 0.3% THC is federally legal in the United States. However, it is essential to check your state’s laws and regulations regarding CBD products.

2. Can I get high from taking CBD oil?

No, CBD is not psychoactive and does not produce a “high” effect like THC, the psychoactive component in cannabis.

3. How long does it take for CBD oil to work?

The time it takes for CBD oil to take effect can vary depending on the method of consumption. Sublingual consumption typically takes effect within 15-30 minutes, while ingesting CBD oil may take 1-2 hours to feel the effects.

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It is essential to check the laws and regulations of the country or state you are traveling to, as some places have strict rules regarding CBD products. Ensure that the CBD oil you are carrying complies with the legal limits of THC content.

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