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Dr Priya Jaisinghani discusses potential questions patients may have about GLP-1 receptor agonists. https://www.medscape.com/viewarticle/glp-1-therapy-not-new-kid-block-2025a10003ph?src=soc_yt --TRANSCRIPT-- Hi. I'm Dr Priya Jaisinghani, an endocrinologist and obesity medicine specialist. Lately there's been a large amount of buzz about GLP-1 therapies, and many patients have questions about them. One common concern I hear is whether these medications are new. The answer is no. GLP-1 receptor agonists are not new. They've actually been around for quite some time. The first GLP-1 medication, exenatide, was approved in 2005, almost 20 years ago. Although their expanded use for weight management is gaining attention now, these medications have a solid history of treating type 2 diabetes. Since then, newer agents such as liraglutide, dulaglutide, semaglutide, and tirzepatide, a dual GIP/GLP-1 receptor agonist, have been developed. These advancements have undergone rigorous clinical trials involving thousands of patients to ensure their safety and efficacy. As healthcare providers, it's our role to answer questions, share evidence, and guide patients to make informed choices for their health. Stay ahead and stay informed with me, Dr J. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/glp-1-therapy-not-new-kid-block-2025a10003ph?src=soc_yt
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Semaglutide, a medication commonly used to treat type 2 diabetes, has gained attention in recent years for its potential to help with weight loss. One of the popular options is the use of semaglutide for weight loss. While the drug has been shown to be effective at helping people shed pounds, finding the optimal dose for weight loss can be a bit tricky. In this article, we will explore the optimal semaglutide weight loss dose and what you should know about it.
Understanding Semaglutide for Weight Loss
Semaglutide is a GLP-1 receptor agonist, which means that it works by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1) in the body. GLP-1 is released in response to food intake and helps to regulate blood sugar levels by stimulating insulin secretion and reducing glucagon secretion. In addition to its effects on blood sugar, GLP-1 also helps to regulate appetite and promote weight loss.
Studies have shown that semaglutide can help people lose weight by reducing appetite, slowing stomach emptying, and increasing feelings of fullness. As a result, people taking semaglutide tend to eat less and therefore consume fewer calories, leading to weight loss over time.
When it comes to using semaglutide for weight loss, finding the right dose is key. The optimal dose can vary depending on individual factors such as age, weight, and overall health. Your healthcare provider will work with you to determine the most effective dose of semaglutide for your weight loss goals.
Factors to Consider
There are several factors that your healthcare provider will consider when determining the optimal dose of semaglutide for weight loss. These include your starting weight, any pre-existing medical conditions you may have, and whether you have any other medications that could interact with semaglutide. Your healthcare provider will also take into account your overall health goals and lifestyle factors when prescribing semaglutide.
It’s important to follow your healthcare provider’s instructions carefully when taking semaglutide for weight loss. The medication should be taken as prescribed, and you should attend regular follow-up appointments to monitor your progress. Your healthcare provider may also recommend incorporating healthy eating and regular physical activity into your weight loss plan to maximize the effects of semaglutide.
While semaglutide can be an effective tool for weight loss, it is not a magic solution. It is important to manage your expectations and understand that weight loss takes time and effort. Semaglutide should be used as part of a comprehensive weight loss plan that includes healthy lifestyle changes for the best results.
Potential Side Effects
Like any medication, semaglutide can cause side effects in some people. Common side effects of semaglutide may include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and tend to improve over time as your body adjusts to the medication. If you experience severe or persistent side effects while taking semaglutide, be sure to contact your healthcare provider.

In rare cases, semaglutide may cause more serious side effects such as pancreatitis or thyroid tumors. It’s important to be aware of the potential risks associated with semaglutide and to notify your healthcare provider if you experience any unusual symptoms while taking the medication. Your healthcare provider will be able to provide guidance on how to manage any side effects and whether it is safe to continue taking semaglutide for weight loss.
In conclusion, the optimal semaglutide weight loss dose can vary depending on individual factors, and it is important to work closely with your healthcare provider to find the right dose for you. Semaglutide can be an effective tool for weight loss when combined with healthy lifestyle changes, but it is not a magic solution. By following your healthcare provider’s instructions and monitoring your progress, you can achieve your weight loss goals with semaglutide.
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Hola a todos: El vídeo de esta semana interesa especialmente a personas con diabetes tipo 2 y obesidad y una especial repulsión a los pinchazos ; ya que os hablo de un fármaco, el semaglutide oral, perteneciente al grupo farmacológico de los agonistas del receptor de GLP-1 , de los que hasta ahora no había formas farmacéuticas orales sino que eran todas parenterales. El semaglutide oral supone una gran revolución en el tratamiento de la diabetes porque hasta ahora todos los agonistas del receptor de GLP-1 que había en el mercado se administraban por vía parenteral subcutánea. Consulta a tu endocrino si el Rybelsus podría ser interesante para ti si tienes diabetes tipo 2 y obesidad. Espero que os resulte de interés.
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How to Lose Fat Naturally — A Christian’s Guide to Fat Loss in Nigeria, By Jesus and Fitness – Port Harcourt Losing fat naturally in Nigeria doesn’t require starvation, foreign diets, or risky pills. At Jesus and Fitness, we believe that a strong body and a sound spirit go hand in hand. This guide is for believers who want to lose body fat naturally, safely, and in alignment with God’s will. Your Body is a Temple — Treat it with Purpose. “Don’t you know that your body is a temple of the Holy Spirit?” – 1 Corinthians 6:19 God gave you your body to serve Him, love others, and fulfill purpose. Excess body fat can lead to tiredness, illness, and low confidence — blocking your assignment. Losing fat is not vanity. It’s stewardship. What Is Natural Fat Loss? Natural fat loss means reducing excess body fat through God-given methods: clean eating, consistent movement, discipline, and rest. No pills, teas, or harmful shortcuts. Why Are Nigerians Gaining Fat? Heavy starchy diets: rice, fufu, yam (in large portions) Late-night eating Sugary drinks: malt, soda, sweetened tea Zero exercise Stress and poor sleep Wrong mindset: “Na my body type” or “I’m married now, who I wan impress?” How to Lose Fat Naturally (The Jesus and Fitness Way) 1. Eat Clean Nigerian Meals Eat more vegetables (ugu, okra), lean proteins (fish, egg), and whole carbs (unripe plantain, brown rice). Avoid fried snacks, excess bread, and soda. 2. Portion Control Saves You You don’t need to starve. Just reduce your portion. Two handfuls per meal is enough. 3. Drink Water Like It’s Your Assignment Water helps burn fat and reduces fake hunger. Aim for 2.5L a day. 4. Exercise 15–30 Minutes Daily Walk, jump, dance to gospel music, do squats or join our gym. Movement burns fat. 5. Sleep Well Your body burns fat better with proper rest. 7–8 hours at night is God-ordained healing time. 6. Fast with Purpose Spiritual fasting helps discipline your body and trains your appetite. Combine it with clean eating for real results. 7. Renew Your Mind Stop saying “I can’t lose weight.” Say: “I am disciplined, strong, and healthy in Jesus’ name.” Best Nigerian Fat-Burning Foods: Ugu (pumpkin leaf) Unripe plantain Beans Fish Okra Eggs Bitterleaf soup (without excess palm oil) Join Jesus and Fitness in Port Harcourt Group classes with music and prayers Faith-based nutrition coaching Clean workouts for Christian families Accountability and transformation Final Word God wants you strong — in spirit and in body. Losing fat naturally honors your Creator and equips you to lead, preach, parent, and prosper. Your body is not a burden; it’s a blessing. Let Jesus and Fitness guide you on your fat loss journey today. Call Us and Sign Up with us now in Portharcourt. Social Medai: @JesusandFitness1st #LoseFatNaturally #FatLossNigeria #WeightLossNigeria #BurnBellyFat #NigerianFitnessJourney #JesusAndFitness #ChristianFitness #FaithBasedFitness #PortHarcourtFitness #FitnessInNigeria #NigerianWeightLossCoach #WeightLossWithoutPills #HealthyNigerianFood #FitnessForChristians #GodlyBodyTransformation