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Semaglutide Pill For Weight Loss An Overview
Beyond the Scales is a short podcast series hosted by Emily, and Fran, who are both Year 4 Medical Students studying in the UK. alongside Mr Lee Humphreys, a Consultant Bariatric Surgeon who practises in the UK.
The aim of the podcast is to dispel common myths surrounding obesity, specifically amongst medical students and other healthcare professionals
In this episode, we discuss the impact that ultra-processed foods have on our ability to control our weight.
Please find the references for the discussion below;
Semaglutide - https://bnf.nice.org.uk/drugs/semaglutide/#important-safety-information
Orlistat - https://bnf.nice.org.uk/drugs/orlistat/
NICE guidelines for obesity management -
https://www.nice.org.uk/guidance/cg189/resources/obesity-identification-assessment-and-
management-pdf-35109821097925
GLP-1 and the brain -
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280675/#:~:text=These%20studies%20ha
ve%20also%20shown,energy%20homeostasis%20and%20autonomous%20functions.
Examples of GLP-1 analogues - https://www.diabetes.org.uk/guide-to-diabetes/managing-
your-diabetes/treating-your-diabetes/tablets-and-medication/incretin-mimetics
Liraglutide weight loss - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358074/
Semaglutide weight loss - https://www.nejm.org/doi/10.1056/NEJMoa2032183
Tirzepatide weight loss - https://www.nejm.org/doi/10.1056/NEJMoa2206038
Summary of clinical trials for GLP-1 receptor agonists -
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509428/
Semaglutide trial - https://www.nejm.org/doi/full/10.1056/NEJMoa2032183
Patient preferences for GLP-1 receptor agonists-
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483112/
FDA evaluation of reports of suicidal thoughts related to GLP-1 receptor agonists -
https://www.fda.gov/drugs/drug-safety-and-availability/update-fdas-ongoing-evaluation-
reports-suicidal-thoughts-or-actions-patients-taking-certain-
type#:~:text=Similarly%2C%20our%20reviews%20of%20the,of%20suicidal%20thoughts%20
or%20actions.
Bariatric Surgery and risk of suicide - https://pubmed.ncbi.nlm.nih.gov/30343409/
Bariatric Surgery and gallstones -
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011673/#:~:text=The%20incidence%20o
f%20gallstone%20formation,recommended%20to%20prevent%20gallstone%20formation
Oral semaglutide phase 3 clinical trials -
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01185-6/abstract
GLP-1 receptor agonist shortage -
https://www.bmj.com/content/384/bmj.q28#:~:text=The%20supply%20of%20glucagon%2
Dlike,demand%20and%20off%2Dlabel%20use.
GLP-1 receptor agonist shortage information - https://www.diabetes.org.uk/guide-to-
diabetes/managing-your-diabetes/treating-your-diabetes/tablets-and-medication/incretin-
mimetics/shortage-FAQs
Unintended and adverse consequences of GLP-1 receptor agonists -
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495825/
NICE guidelines Phentermine (discontinued) -
https://www.nice.org.uk/guidance/discontinued/gid-tag439
New clinical trials looking at obesity medications -
https://www.clinicaltrialsarena.com/features/obesity-trials-to-watch/?cf-view
Weight regain after stopping semaglutide - https://pubmed.ncbi.nlm.nih.gov/35441470/
Devon 2023 Tier 3 weight management average waiting times -
https://www.royaldevon.nhs.uk/media/ieibfrgr/foi-rdf1222-23-tier-3-tier-4-weight-
management-services.pdf
Weight loss medications and bariatric surgery -
https://link.springer.com/article/10.1007/s13679-021-00425-1
This video is aimed for use as an educational video and should not be taken as medical advice. Any ideas raised within this video should be discussed with a healthcare professional before making any changes.
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