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Dr David Johnson highlights new preoperative recommendations to protect against consequences of some diabetes and weight loss drugs that delay gastric emptying. https://www.medscape.com/viewarticle/994762?src=soc_yt -- TRANSCRIPT --- Hello. I'm Dr David Johnson, professor of medicine and chief of gastroenterology in Eastern Virginia Medical School in Norfolk, Virginia. Recent national media attention has focused on the gastrointestinal (GI) side effects of glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs are used to treat type 2 diabetes and weight loss. The GI side effects include nausea, vomiting, and gastroparesis-like symptoms. I wanted to emphasize two key points especially important to clinicians providing this class of therapy. One: Clinicians need to be increasingly aware of the potential GI side effects and inform their patients when they start to prescribe these medications. And two: The American Society of Anesthesiologists (ASA) has recently released consensus-based recommendations for preoperative assessment and management of adults and children undergoing surgery who are taking these medications. The recommendations also apply to endoscopic procedures whereby anesthesia will be delivered. Gastric Impact of GLP-1 Agonists What are these GLP-1 agonists? The drugs for weight loss include liraglutide (Saxenda and Victoza) and semaglutide (Ozempic, Wegovy, Rybelsus, among others). The type 2 diabetes medications include semaglutide, dulaglutide (Trulicity), and exenatide (Byetta, Bydureon BCise), among others. They can be taken daily or by injection once a week. The GLP-1 agonist drug class works at the GI level to increase insulin secretion and decrease glucagon release, both of which mediate glycemic control, particularly postprandially. The drugs slow the gastric motility through decreased peristalsis and increased tonic contractility of the pylorus, essentially causing a delay in gastric emptying. Dr Michael Camilleri and his colleagues at the Mayo Clinic, in Rochester, Minnesota, conducted a small randomized, placebo-controlled double-blind study of the GLP-1 agonist liraglutide to investigate the mechanism of weight loss in patients who were overweight. They showed that there was a diminution in gastric emptying over 16 weeks in patients taking liraglutide. They found evidence of tachyphylaxis, but the rate of gastric emptying of solids remained slow compared with placebo, even at 16 weeks. Despite the observed waning of the gastric impact, we just don't know how long significant side effects persist when patients stop the drug for good. There are some reports of patients with protracted symptoms a year or more after they've stopped their GLP-1 agonist medications. Guidance for Preoperative Management These drugs would commonly be reviewed before patients go through procedures, and we need to be better aware as we start to see these patients for endoscopy. The ASA recommendations address the potential consequences of delayed gastric emptying and provide guidance for preoperative management of these drugs to prevent regurgitation and pulmonary aspiration of gastric contents. In patients on daily dosing, the ASA recommends holding these agents the day prior to the procedure. For patients on weekly dosing, the recommendations suggest withholding the dose a week before the procedure. Importantly, this should be in consultation with their diabetologist, just to assess any need for a bridging therapy to avoid hypoglycemia. On the day of the procedure, if GI symptoms, such as severe nausea, vomiting, retching, abdominal pain, and bloating, are present, clinicians should consider delaying the elective procedure and discuss the risks of the potential risks for aspiration. If the patient has no symptoms and the GLP-1 agonist has been withheld as advised, then you should proceed as usual. But if the patient has no symptoms and has not held their GLP-1 agonist, you should proceed with what the anesthesiologists call the "full stomach" precaution, which considers patients at potentially high risk for aspiration. There's a way of checking for that. Some centers can do a quick ultrasound on the stomach and see if there's food, debris, or liquid, and if that is not the case, they could proceed with no delay. But if there is no way to check gastric contents, then you should manage accordingly, which may require intubation or postponing an elective procedure for another day. These are new and changing issues. In our world as gastroenterologists, we should be considering — very strongly — mitigating strategies to protect the patients on this wonderful class of therapy. Sometimes these drugs can have significant side effects that we need to at least be aware of. Nothing is perfect, but let us be better informed. https://www.medscape.com/viewarticle/994762?src=soc_yt
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Exploring the Impact of Shark Tank on Keto Products
In recent years, the keto diet has gained immense popularity among individuals looking to lose weight and adopt a healthier lifestyle. This low-carb, high-fat eating plan has not only attracted millions of followers but has also inspired a wave of innovative products designed to make the keto journey easier and more enjoyable. One such platform that has been instrumental in bringing these products to the mainstream level is the television show “Shark Tank.” Since its inception, “Shark Tank” has provided countless entrepreneurs with a platform to showcase their businesses and secure investments from seasoned investors, also known as “sharks.” This article delves into five of the most successful keto products that have graced the screen of “Shark Tank,” examining their unique offerings, the entrepreneurs behind them, and their overall impact on the keto community.
The keto diet focuses on significantly reducing carbohydrate intake while increasing fat consumption, placing the body in a metabolic state known as ketosis. In ketosis, the body efficiently burns fat for energy instead of relying on carbohydrates. As this diet requires adherence to specific macronutrient ratios, various products have emerged to support individuals in maintaining their keto lifestyle. However, finding suitable products that align with the diet’s principles can be challenging. This is where “Shark Tank” has played a pivotal role, helping keto entrepreneurs gain visibility and recognition in a competitive market.
Through each episode, viewers witness the journey of passionate entrepreneurs as they pitch their products to a panel of wealthy investors, seeking not only capital but also mentorship and industry connections. The success stories that unfold often highlight not only innovative solutions for the keto community but also the resilience and hardworking nature of the entrepreneurs behind them. By analyzing these success stories, we can gain insights into how these products have transformed the landscape of keto eating and helped countless individuals achieve their health and fitness goals.
Keto Breads: A Game-Changer for Low-Carb Dieters
One of the most transformative products that emerged from “Shark Tank” for those following a keto lifestyle is keto bread. Traditional breads are typically high in carbohydrates, making them unsuitable for keto dieters. However, the introduction of keto breads, which are specifically designed to be low in carbs while still providing the familiar taste and texture of regular bread, has been a revolutionary addition to the market. Entrepreneurs behind these products have worked diligently to create breads that do not compromise on flavor or experience while aligning with the dietary restrictions of keto.
These keto bread products often incorporate alternative ingredients such as almond flour, coconut flour, psyllium husk, and various seeds to achieve the desired low-carb profile. Many brands featured on “Shark Tank” have also focused on ensuring that their breads remain free from gluten, artificial ingredients, and preservatives. This not only makes them suitable for keto dieters but also appeals to a broader audience interested in gluten-free options. The success of these products demonstrates a growing consumer demand for healthier alternatives to traditional foods without sacrificing taste.
Moreover, the appeal of keto bread goes beyond just being a gluten-free option; it provides a sense of normalcy for those who miss traditional bread-based meals. With keto bread, dieters can enjoy sandwiches, toast, and other popular dishes while maintaining their dietary goals. As more keto bread brands continue to gain exposure through “Shark Tank,” the impact on the low-carb community is significant, offering individuals more diverse meal options and enhancing their overall dietary experience.
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Keto Snacks: Keeping Cravings at Bay
Keto snacks have carved out a niche within the market as essential offerings for anyone on a low-carb diet. The challenge of sticking to a keto lifestyle often lies in the struggle to manage cravings for traditional snacks and treats. Recognizing this gap, entrepreneurs on “Shark Tank” have introduced a variety of keto-friendly snack options, ranging from chips to chocolates, designed to satisfy cravings without derailing one’s progress. These snacks typically utilize ingredients that are low in carbs and sugars while being high in healthy fats and protein.
The secret to success for many keto snack brands lies in their ability to replicate the taste and texture of popular snacks while using alternative ingredients that align with the keto principles. For instance, some companies have developed high-fiber, low-carb chips using ingredients like cheese, flaxseed, and even vegetables. Others focus on sweet snacks, creating chocolate bars or nut-based desserts that deliver on flavor without the sugar and carbs associated with traditional sweets. This innovation not only caters to the cravings of keto dieters but also attracts a wider audience looking for healthier snacking options.
The proliferation of keto snacks available today, many of which gained recognition from their appearances on “Shark Tank,” showcases the ever-evolving landscape of food products geared towards health-conscious consumers. The success of these snacks has made it easier for individuals to adhere to their dietary restrictions while enjoying the flavors they love. This shift not only enhances the keto experience but also helps normalize low-carb eating in everyday life, encouraging more people to adopt the keto diet.
Keto Meal Kits: Effortless Low-Carb Cooking
For individuals who are new to the keto diet or simply looking for convenient meal solutions, keto meal kits have emerged as a helpful way to navigate the complexities of low-carb cooking. Entrepreneurs featured on “Shark Tank” have capitalized on this demand by creating meal kits that come pre-portioned with all the ingredients needed to prepare delicious and satisfying keto meals that are ready in a matter of minutes. These meal kits take the guesswork out of cooking while adhering to strict dietary guidelines.
One significant advantage of keto meal kits is that they cater to various tastes and preferences, offering a range of cuisines and meal options—from Italian to Asian-inspired dishes. Each kit comes with simple instructions that make it easy for anyone, regardless of culinary experience, to create wholesome keto meals. By emphasizing quality ingredients and streamlined preparation, these kits invite more people to engage with the keto lifestyle without feeling overwhelmed.
Furthermore, the presentation of these meal kits has greatly contributed to their success. Many brands highlight the use of organic, non-GMO ingredients, which resonate with health-conscious consumers. By ensuring that the meals are not only keto-friendly but also nutritious and delicious, these meal kits have been able to establish a loyal customer base. The growth of this sector in the keto market highlights the increasing demand for convenient, healthy meal solutions that support busy lifestyles.
Keto Supplements: Aiding the Journey to Ketosis
To support those on the keto diet, a variety of supplements have emerged as key players in helping individuals transition into and maintain ketosis. Certain entrepreneurs showcased their brands on “Shark Tank,” offering products designed to enhance the keto experience through supplements that provide essential nutrients while supporting overall wellness. These supplements often include exogenous ketones, MCT oils, and electrolyte blends that can help manage energy levels and cravings during the initial stages of the diet.

Many of these keto supplements aim to offer convenience for individuals who may struggle with meeting their nutrient needs strictly through dietary sources. For example, exogenous ketone supplements can help accelerate the process of entering ketosis, providing users with an immediate energy boost and reducing the experience of “keto flu” commonly associated with transitioning into the diet. This has made keto supplements particularly popular among those just starting their keto journey.
Moreover, the success of keto supplements featured on “Shark Tank” has paved the way for increased awareness about the importance of proper supplementation for sustainable health. These products often highlight their quality and effectiveness, appealing to individuals committed to optimizing their keto experience. The promotion of these supplements through entrepreneurial efforts has contributed not only to the success of individual brands but also to the broader growth of the keto industry.
The Evolution of Keto Products and Their Future Potential
In recent years, the keto product landscape has evolved dramatically, driven by consumer demand for healthier, low-carb options. The success of keto-focused brands on “Shark Tank” reflects the growing recognition of the keto diet by entrepreneurs and investors alike. As more products enter the market—from keto-friendly breads to meal kits and snacks—the future of keto offerings looks promising.
As the keto trend continues to grow, the potential for innovation remains significant. New technologies and food science advancements pave the way for the development of even more creative and appealing keto products. Brands that can successfully marry health benefits with flavors and convenience will likely flourish in this expanding market. Entrepreneurs who are able to leverage lessons learned from their “Shark Tank” experiences can find themselves at the forefront of a burgeoning industry, setting trends that could shape the future of dietary choices.
Additionally, the increasing awareness surrounding health conditions linked to poor dietary habits may further enhance the demand for keto products. With obesity and type 2 diabetes on the rise, more individuals are seeking sustainable and effective ways to improve their health through diet. This context ensures a steady growth trajectory for keto-focused businesses in the years to come. As awareness continues to spread, so too will the opportunities for aspiring entrepreneurs to create products that resonate with a health-conscious consumer base, cementing the keto lifestyle as a staple within the wider food industry.
Reflecting on the Keto Journey and Consumer Choices
The journey of keto products highlighted on “Shark Tank” serves as an inspiration for entrepreneurs and followers of the diet alike. As individuals navigate their keto experiences, they can draw motivation from the success stories of those who embarked on similar paths. The challenges and triumphs of these entrepreneurs underscore the importance of resilience, creativity, and dedication when it comes to launching successful products.
Moreover, the diversity of keto products available today demonstrates a paradigm shift in consumer preferences toward healthier eating choices. As the demand for keto products increases, it is essential for consumers to remain informed and make choices that align with their specific dietary needs and goals. Understanding the benefits of each product and how they fit into a keto lifestyle allows individuals to make educated decisions and fully embrace the advantages of low-carb eating.
In summary, the keto movement has experienced tremendous growth, with many products finding a home on platforms like “Shark Tank.” The significant impact of these entrepreneurs on the keto community highlights the richness of possibilities that accompany innovative thinking. As consumers seek to improve their health through dietary changes, the rise of keto products will undoubtedly continue to shape the future of nutrition and wellness.
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With the rise of influencer marketing, celebrities are increasingly using their fame to promote products, including diet products. One such celebrity is Oprah Winfrey, whose endorsement of “Oprah Gummies for Weight Loss” has created a buzz in the weight loss industry. In this article, we will take a closer look at Oprah Gummies for Weight Loss Reviews and explore the impact of celebrity influence on diet products.
Celebrity Endorsement: Oprah and Weight Loss
Oprah Winfrey, a media mogul and talk show host, has been open about her struggles with weight loss and body image throughout her career. Her journey to find balance and maintain a healthy lifestyle has resonated with millions of people around the world. When Oprah endorses a product, it often garners attention and credibility due to her influence and reputation.
Enter “Oprah Gummies for Weight Loss,” a dietary supplement that claims to help individuals lose weight by curbing appetite and boosting metabolism. With Oprah’s stamp of approval, these gummies have generated a significant amount of interest among consumers seeking a quick and easy solution to their weight loss goals.
But do Oprah Gummies for Weight Loss actually work, or are they just another celebrity-endorsed product with exaggerated claims? Let’s delve into some reviews and testimonials to get a better understanding of the effectiveness of these diet gummies.
Consumer Reviews and Testimonials
Many consumers who have tried Oprah Gummies for Weight Loss have shared their experiences online, providing valuable insights into the product’s efficacy. Some users claim that the gummies helped suppress their appetite, leading to reduced calorie intake and subsequent weight loss. They appreciate the convenience of the gummies and the natural ingredients used in the formula.
On the other hand, some users have expressed skepticism about the product’s claims, stating that they did not experience any significant weight loss while taking the gummies. They question whether the results are truly due to the product or simply a result of lifestyle changes such as diet and exercise. It is crucial to consider individual factors such as metabolism and body composition when evaluating the effectiveness of any weight loss product.
Overall, the reviews for Oprah Gummies for Weight Loss are mixed, with some users reporting positive results and others feeling disappointed in the product’s performance. As with any dietary supplement, it is essential to consult with a healthcare professional before incorporating it into your weight loss regimen and to manage your expectations regarding the outcomes.
Impact of Celebrity Endorsement on Diet Products
Celebrity endorsements can have a powerful influence on consumer behavior, as individuals are more likely to trust and purchase products that are recommended by their favorite stars. When a well-known figure like Oprah Winfrey supports a diet product, it can lend credibility and legitimacy to the brand, potentially leading to increased sales and brand awareness.
However, it is essential for consumers to approach celebrity endorsements with a critical eye and consider factors such as product efficacy, safety, and alignment with their personal health goals. While Oprah Gummies for Weight Loss may have the backing of a beloved celebrity, it is crucial to conduct thorough research and seek out unbiased reviews to make an informed decision about whether to try the product.
In conclusion, celebrity influence on diet products such as Oprah Gummies for Weight Loss can shape consumer perceptions and purchasing decisions. While celebrity endorsements can undoubtedly boost a product’s visibility, it is essential for consumers to exercise caution and conduct their due diligence before investing in any weight loss supplement.
Overall, Oprah Gummies for Weight Loss Reviews highlight the complexities of celebrity influence on diet products and underscore the importance of informed decision-making when it comes to managing weight and wellness. Whether you are swayed by celebrity endorsements or prefer to rely on scientific evidence, the key is to prioritize your health and well-being above all else.