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Get 20% More Appetite Suppression on GLP-1 - Did you know the spot you pick for your GLP-1 shot can change how much medication actually reaches your bloodstream? In today’s breakdown, I compare the three main GLP-1 injection sites (belly, thigh, and arm) and show the results of the study done by Lilly. Spoiler alert: One spot gives you almost 20% more appetite suppression than the other. You’ll see exactly how I alternate sides and what to expect if you’re brand-new to GLP-1 injections. By the end, you’ll have a clear, evidence-backed plan for choosing the best GLP-1 injection sites for your own goals. 🔗 Subscribe to TDL: youtube.com/@TodayDaniLearned?/sub_confirmation=1 Subscribe for more videos where I break down complex topics into plain English! 🕔 TIMESTAMPS 00:00 Why GLP-1 site matters? 00:28 Eli Lilly Study Findings 01:27 My Injection Routine 📌 DISCLAIMER This video is for informational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting any medication or treatment. I am not sponsored or affiliated with any of the brands mentioned. Some links may be affiliate links at no extra cost to you. #glp1 #glp1weightloss #glp1injections #wegovy #zepbound #moujaro #ozempic #semaglutide #tirzepatide #glp1injectionsites
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The physical issues associated with being overweight/obese are well-known. Are there also psychiatric consequences associated with weight issues? Discover the answer to this question and the potential impact of GLP-1 agonists with Tina Turneuron! Focuser videos are a unique part of NEI live meetings. Preceding each lecture, these videos provide an entertaining introduction for the presentation to come. To register for an upcoming NEI Meeting, please visit https://nei.global/meetings Originally presented at the 2024 NEI Congress. Interested in Psychopharmacology? Check out the NEI Master Psychopharmacology Program: https://nei.global/mpp Follow us on Facebook: https://nei.global/facebook Follow us on LinkedIn: https://nei.global/linkedin Follow us on X: https://nei.global/twitter Follow us on Instagram: https://nei.global/instagram Listen to NEI Podcast! Spotify: https://nei.global/podcastspotify Apple Podcast: https://nei.global/podcastapple Stay updated with email alerts: https://nei.global/updates
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incretin effect| incretin effect glp-1| incretin effect explained| incretin effect in diabetes| incretin hormones| incretin based therapy of diabetes
▪ Incretins are a group of metabolic hormones that stimulate a decrease in blood glucose levels. Gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are the two primary incretin hormones secreted from the intestine on ingestion of glucose or nutrients to stimulate insulin secretion from pancreatic β cells. The major mechanism of metabolism of the incretins is cleavage by dipeptidyl peptidase 4 (DPP4), an enzyme that is ubiquitously expressed, including in endothelial cells.
▪ Two pharmacological approaches have been taken to enhance the incretin effect in type 2 diabetes. One approach is to administer GLP-1 'analogues' (GLP-1 receptor agonists) that are resistant to cleavage by DPP4. The other approach is to inhibit DPP4 activity. This effectively increases the half-life and therefore the circulating concentrations of the incretins.
▪ In summary, Ingested glucose causes secretion of incretins from GI tract. These ingredients then increase insulin secretion from the pancreas. Anti-diabetic drugs targeting this mechanism are glp1 analogues and dpp4 inhibitors. And in this way, by increasing insulin secretion, the incretins lower blood glucose.
Chapters:
0:00 - Insulin Secretion Mechanism
0:42 - Incretin Effect
1:10 - Incretin Hormones
1:26 - Glucagon-like peptide-1 (GLP-1) Hormone
2:19 - Problem in Diabetes
2:35 - GLP-1 analogues and DPP-4 inhibitors
3:24 - Summary of Incretin Effect
incretin hormones, incretin effect, incretin effect glp-1, incretin effect explained, incretin effect in diabetes, insulin, diabetes, glucagon like peptide 1, incretin based therapy of diabetes, incretin pathway, incretin and glp-1, glp 1 analogs, dpp4 inhibitors, sitagliptin, vildagliptin, exenatide, liraglutide, oral antidiabetic drugs, mechanism of insulin secretion, insulin secretion, insulin physiology, insulin pharmacology, diabetes mellitus, medicine, pharmacyd by asim
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"Content is For Informational & Education Purpose Only, Creamed From Various Authentic Books of Pharmacy & Medicine. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition."
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GLP-1 medications like Novo Nordisk's Wegovy and Ozempic are taking the market by storm. With demand soaring, many patients are realizing these medications are either not being covered or simply too expensive. Is this all due to provider greed or is the issue more complicated? In this episode of CareTalk, David E. Williams and John Driscoll discuss how the growing demand for weight-loss drugs is creating a conundrum for providers, forcing them to decide between avoiding the costs associated with at-risk patients or investing upfront for long-term savings. This episode is brought to you by BetterHelp. Give online therapy a try at https://betterhelp.com/caretalk and get on your way to being your best self. As a BetterHelp affiliate, we may receive compensation from BetterHelp if you purchase products or services through the links provided. TOPICS (0:38) Sponsorship (2:06) Obesity in America (2:40) The State of Insurance Coverage for GLP-1s (3:27) Background on Obesity Drugs (4:45) Formation of GLP-1 Use (7:20) The Cost Conundrum of Weight-Loss Drugs (10:16) How Insurance Impacts Weight-Loss Drug Coverage (11:30) Understanding Adverse Selection (14:30) How Insurers Prevent Coverage (15:04) Decisions on Weight-Loss Drug Coverage (16:07) What Makes GLP-1s Unique for Cost Coverage (18:00) Will Weight-Loss Drugs Become Cheaper? (21:22) Medicare's Role in Weight-Loss Drugs (22:17) Examining Side Effects of Weight-Loss Drugs 🎙️⚕️ABOUT CARETALK CareTalk is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy. 📥 GET IN TOUCH Become a CareTalk Podcast sponsor: https://www.caretalkpodcast.com/work-with-us Guest appearance requests: https://www.caretalkpodcast.com/contact-us Visit us at https://www.caretalkpodcast.com 📲 FOLLOW Spotify: https://open.spotify.com/show/2GTYhbN...... Apple Podcasts: https://podcasts.apple.com/us/podcast...... Follow us on LinkedIn: https://www.linkedin.com/company/caretalk-podcast 🗞️ Subscribe to our newsletter: https://www.caretalkpodcast.com/newsl... 🛒 Shop for official CareTalk merch: https://www.caretalkpodcast.com/categ... ⚙️ Produced by Grippi Media: https://www.grippimedia.com #healthcarepodcast #healthcare #weightloss #weightlossdrugs #drugpricing #GLP1 #medicalcosts
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Harnessing Personal Strength: Kelly Clarkson’s Journey
Kelly Clarkson, the original American Idol winner, has been an inspiration to many not just for her powerful voice but also for her candid discussions about her personal challenges, including weight loss. Over the years, Clarkson has been open about her struggles with body image and the pressures of fame in the entertainment industry. What makes her journey particularly compelling is how she has navigated the often rocky terrain of self-acceptance and wellness, all while in the public eye, which adds an additional layer of complexity to her transformation.
Weight loss is a topic that resonates with many, and Clarkson’s journey is relatable for people from all walks of life. She experienced ups and downs, eventually finding a path that worked for her—something that many individuals struggling with weight can understand. In a revealing interview with Dr. Oz, Clarkson delved deep into the specifics of her journey, providing insights that not only reflect her own experience but also offer invaluable lessons for others. Her candidness about her struggles with food, diet, and mental health demonstrated a level of vulnerability that is not often seen in the industry, making her story even more impactful.
During the interview with Dr. Oz, Clarkson tackled the issue of body positivity and personal accountability, emphasizing the importance of mental health in the weight loss journey. She shared that her transformation was not merely about physical appearance but centered on regaining control of her life. The narrative she shared was one of empowerment—a reminder that true health encompasses both physical and emotional well-being. By discussing her journey so openly, Clarkson has not only inspired her fans but has also contributed to a larger societal conversation about weight, beauty standards, and self-worth.
The Catalyst: Dr. Oz Interview as a Turning Point
The Dr. Oz interview marked a significant milestone in Kelly Clarkson’s weight loss journey. It served as a platform for her to candidly share her past struggles and current triumphs. The conversation revealed Clarkson’s thoughts on celebrity culture and its often unrealistic beauty standards, which had plagued her for years. Through this open dialogue, she brought attention to the mental toll that comes with constant scrutiny over one’s body and appearance.
During the interview, Clarkson expressed her frustration with the relentless pressure to conform to society’s ideals of beauty. She detailed how these pressures influenced her relationship with food, often leading to emotional eating and disengagement from healthy habits. Clarkson candidly illustrated how her self-esteem suffered as a result, creating a cycle of negativity that further complicated her challenges. This moment of honesty resonated with many viewers who understand that they are not alone in their struggles.
Crucially, the Dr. Oz interview was not just about acknowledging struggles; it was a defining moment in which Clarkson highlighted her commitment to change. She discussed practical approaches to her weight loss journey, such as adopting healthier eating habits and engaging in regular exercise. The significance of this narrative lies in its transformative power, as Clarkson became a testament to resilience and personal evolution, encouraging others to prioritize their own health and well-being.
From Struggle to Strength: Food and Fitness Regimen
As Clarkson embarked on her weight loss journey, she discovered the importance of a balanced approach to food and fitness. By reassessing her relationship with food, she began to understand that nourishment plays a crucial role in her well-being. By focusing on whole foods and learning to appreciate the nutritional value of what she consumed, Clarkson made a conscious effort to create a healthier lifestyle.
The journey towards healthier eating habits was not without its challenges. Kelly shared her experiences with cravings and the temptation to revert to old habits, reminding viewers that weight loss is often about finding balance rather than complete deprivation. Her philosophy became rooted in moderation, steering away from extreme dieting and embracing a more sustainable approach to food. This shift empowered her to make choices that aligned with her goals while still enjoying the foods she loved.
In tandem with her dietary changes, Clarkson explored various fitness regimes, finding joy in physical activity. From dancing to structured workouts, she discovered that movement could be enjoyable rather than a chore. By connecting fitness to her passions, she transformed what was once a daunting task into an invigorating part of her daily routine. The synergy of healthy eating and enjoyable physical activity formed the cornerstone of her successful transformation, proving that well-being is holistic and uniquely personal.
Mental Health as a Pillar of Well-being
One of the most pivotal aspects of Kelly Clarkson’s weight loss journey is her emphasis on mental health. In her interview with Dr. Oz, she addressed the deep connection between mental health and physical well-being, illustrating that true transformation isn’t solely about the number on a scale. Clarkson shared that her journey was also about cultivating a positive mindset, recognizing harmful patterns, and engaging in self-care practices that nurture her emotional health.
Clarkson’s journey served as an affirmation of how intertwined self-acceptance and self-love are with achieving personal goals. Acknowledging feelings of stress and anxiety, she sought therapeutic avenues to address these issues, realizing that mental well-being directly impacted her physical health. By prioritizing mental health, Clarkson created a supportive environment that allowed her to navigate the challenges of weight loss with resilience.
This newfound focus on mental health translated into practical changes in her daily life. Introducing mindfulness and relaxation techniques became an integral part of her routine, helping her to process emotions and stresses that previously contributed to unhealthy eating habits. Clarkson’s journey resonates as a reminder that true wellness encompasses not just the body but also the mind, encouraging others to adopt similar holistic practices for lasting change.
Impact and Inspiration: A Legacy Beyond Weight Loss
Kelly Clarkson’s journey resonates beyond the realm of weight loss, as it serves as a powerful narrative of resilience and empowerment. Her openness about her struggles has inspired many to embark on their own wellness journeys, reminding them that it is normal to face obstacles. Clarkson’s transformation demonstrates that health is not a linear path, but a complex journey filled with highs and lows.
Through her candid discussions and public advocacy for self-acceptance, Clarkson has paved the way for larger conversations about body image, mental health, and societal expectations. By dismissing toxic beauty standards prevalent in the entertainment industry, she has become a beacon of change, urging others to define their worth beyond appearance. Clarkson’s influence extends to young women and fans worldwide, encouraging them to appreciate their unique beauty and embrace their health journeys.
Ultimately, Kelly Clarkson’s legacy is rooted in her resilience and her dedication to being unapologetically herself. Her story fosters a sense of community and support among those grappling with similar issues, proving that change is possible with commitment and self-love. Clarkson has not only changed her life but has also ignited a movement advocating for acceptance and wellness, making her a role model for generations to come.
Conclusion and Reflections on Clarkson’s Journey
Kelly Clarkson’s weight loss journey is a rich narrative that intertwines vulnerability, self-discovery, and personal empowerment. The Dr. Oz interview acted as a catalyst for deeper conversations about body image and mental health, reinforcing the idea that wellness is not merely a destination but a lifelong pursuit. Through her experiences, Clarkson redefines the parameters of health, illustrating that it encompasses much more than physical appearance.
Her candid sharing of struggles and triumphs serves as a valuable resource for those navigating their own challenges. Clarkson’s emphasis on embracing a balanced diet, engaging in enjoyable fitness, and prioritizing mental health reiterates the importance of holistic wellness. It inspires others to pursue their own journeys of transformation, reminding them that setbacks are merely stepping stones toward greater self-acceptance and well-being.
As she continues to thrive in the music industry, Clarkson’s story reinforces the message that anyone can reclaim their health. Through honesty, resilience, and determination, she has become more than a singer; she is a symbol of hope for many individuals striving for betterment in their own lives. Ultimately, her journey exemplifies how empowerment can arise from embracing the full spectrum of human experience, inviting everyone to redefine success on their own terms.
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