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A major issue with GLP - 1 medications is their cost. Most insurances are not covering these for the treatment of obesity or overweight. Even for many diabetics, the cost is substantial with co-pays and deductibles. The brand drugs can run between $1000 and $2000 dollars monthly. During the time when the major pharmaceutical companies could not produce enough of the drugs to supply the need, the FDA has allowed certified compounding pharmacies to make and dispense the medications. Once the shortage is over, these pharmacies may no longer produce and dispense the medications. This will cause a major disruption in patients receiving these life saving medications. The cost from compounding pharmacies is high but only about 1/3 to 1/2 the cost of the large pharmaceutical companies. These medications can easily be over $1000 monthly. Hopefully, there can be some modification to allow for the less expensive meds to be obtained.

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The Servier pharmaceutical group was found guilty by a Paris court on Monday, as the trial over one of the biggest health scandals to have hit France came to a close. More than ten years after the opening of a judicial investigation and eighteen months after the start of the trial, the drugmaker was found guilty of involuntary manslaughter and aggravated fraud for selling the weight loss pill 'Mediator,' which was blamed for hundreds of deaths. "It was a historic trial, it becomes for me, a historic judgment. Even if it is not entirely satisfactory, it is nonetheless true that this is the first time that a laboratory has been so severely condemned," said victims' lawyer Jean-Christophe Coubris. "I hope that the laboratories will hear both the suffering of the victims and the condemnation that has been pronounced against the Servier laboratories," the lawyer added. "Servier laboratories are ordered to pay the victims around 160 million euros (188 million USD). This is extremely low compared to the real profit made by the Mediator, around 400 million euros (470,9 million USD) during the 14 years of undue marketing," said Charles-Joseph-Oudin, lawyer of Michel Due, one of the victims. Servier was also sentenced to a fine of 2.7 million euros (3,18 million USD). Jean-Philippe Seta executive of Servier pharmaceutical group was sentenced to four years of suspended imprisonment, as well as a fine of 90,600 euros (106,67 USD). At least 500 people died of heart valve problems due to the Mediator's active ingredient, according to France's health ministry. The drug was on the market for 33 years before it was pulled in 2009. Credit: Ruptly #pharma #servier #mediator

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