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In this episode of The Pound of Cure Weight Loss podcast, Dr. Matthew Weiner and Zoe Schroeder, RD discuss the key components of achieving sustainable weight loss through a combination of GLP-1 medications, weight loss surgery, and effective nutritional strategies. Dr. Weiner, a leading bariatric surgeon and non-surgical weight loss specialist, and Zoe, a registered dietitian, share their holistic approach to weight loss and weight management from their Tucson, Arizona practice. At the heart of their philosophy is an emphasis on sustainable weight loss strategies that go beyond quick fixes. Whether it’s through weight loss surgery like sleeve gastrectomy and gastric bypass, or the use of GLP-1 medications such as Zepbound and Wegovy, or a nutrient-dense diet like the Metabolic Reset Diet, Dr. Weiner and Zoe stress the importance of nutrition and long-term support. Patient Success Story: Weight Loss Without Wegovy The episode features a powerful success story of Joey, a patient who achieved significant weight loss without surgery or GLP-1 medications. Joey’s diet was terrible. He came to the practice hoping to get on GLP-1 medications. But, due to the shortages, Dr. Weiner recommended Joey start on the Metabolic Reset Diet - a sustainable weight loss strategy focused on a whole foods like fruits, vegetables, nuts, seeds, beans, and lean protein. Within a couple weeks Joey was dropping weight easily. In less than a year he had reached his goal weight without the use of GLP-1 medications or surgery. His journey underscores how patients can lower their weight set point and maintain their results through lifestyle changes alone. The Role of GLP-1 Medications in Sustainable Weight Loss We also delve into the role of GLP-1 medications in promoting sustainable weight loss. With Belgium's recent ban on Ozempic for weight loss, Dr. Weiner and Zoe discuss the bias against treating obesity as a medical condition. It can leave patients feeling helpless and alone, blaming themselves for a disease that is largely outside of their control. We also explore alternatives to Ozempic, Wegovy, Mounjaro and Zepbound with the use of compounded GLP-1 medications like Semaglutide and Tirzepatide. We weigh the pros and cons of compounded medications and discuss the importance of combining these medications with the right nutrition to maximize success. Slow Weight Loss After Surgery and Managing GLP-1 Side Effects Listeners are reassured that slow weight loss and weight loss stalls after weight loss surgery is normal and part of the body's natural process. Dr. Weiner highlights how consistency in your nutrition is crucial in overcoming plateaus. Zoe provides practical tips on managing side effects of GLP-1 medications, such as nausea and headaches, by focusing on clean eating and whole foods. Optimizing Your Diet for Sustainable Weight Loss The episode concludes with advice on building sustainable weight loss strategies through nutrition. Zoe emphasizes the importance of choosing plant-based proteins and whole foods over highly processed options, while Dr. Weiner reinforces the power of a mostly plant-based diet in long-term success, whether or not you're using GLP-1 medications or undergoing weight loss surgery. Through their engaging discussions, Dr. Weiner and Zoe offer listeners a comprehensive guide to achieving lasting weight loss by combining GLP-1 medications, weight loss surgery, nutrition, and sustainable weight loss strategies. Their holistic approach is grounded in practical, science-backed advice to help individuals navigate their unique weight loss journeys.

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With the growing prevalence of obesity around the world, many people are searching for effective ways to lose weight and improve their overall health. One potential option that has gained attention in recent years is the use of semaglutide, a medication originally developed to treat type 2 diabetes. Studies have shown that semaglutide may also be effective for weight loss, making it an attractive option for individuals looking to shed excess pounds.
Benefits of Using Semaglutide for Weight Loss
Semaglutide works by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1), which helps regulate blood sugar levels and appetite. By increasing the levels of GLP-1 in the body, semaglutide can help reduce hunger and food intake, leading to weight loss.
In clinical trials, patients who took semaglutide experienced significant weight loss compared to those who took a placebo. Some individuals lost as much as 15-20% of their body weight, making semaglutide one of the most effective weight loss medications currently available.
Unlike other weight loss drugs, semaglutide is administered as a once-weekly injection, making it convenient and easy to use. This can be especially appealing for individuals who may struggle to take daily medications or adhere to strict diet and exercise regimens.
Potential Risks and Drawbacks of Using Semaglutide
While semaglutide may offer significant benefits for weight loss, it is not without risks. Like all medications, semaglutide can cause side effects, including nausea, vomiting, and diarrhea. Some individuals may also experience changes in their sense of taste or gastrointestinal discomfort while taking the medication.
Additionally, semaglutide is a prescription medication that is not suitable for everyone. Individuals with a history of pancreatitis, thyroid cancer, or certain other medical conditions may not be good candidates for treatment with semaglutide. It is important to consult with a healthcare provider before starting any new medication, including semaglutide.
Some individuals may also be concerned about the cost of semaglutide, as it can be expensive and may not be covered by insurance. It is important to weigh the potential benefits of the medication against the cost and determine if it is a feasible option for long-term weight management.
Considerations for Using Semaglutide for Weight Loss
Before starting treatment with semaglutide, it is important to have a thorough discussion with a healthcare provider about the potential risks and benefits of the medication. A healthcare provider can help determine if semaglutide is a suitable option for your individual needs and develop a personalized treatment plan to help you achieve your weight loss goals.
It is also important to understand that semaglutide is not a magic bullet for weight loss and should be used in conjunction with a healthy diet and regular exercise. While the medication can help support weight loss efforts, it is not a substitute for making lifestyle changes that promote overall health and well-being.
Ultimately, the decision to use semaglutide for weight loss is a personal one that should be made in consultation with a healthcare provider. By weighing the potential benefits and risks of the medication, you can make an informed choice about whether semaglutide is the right option for you.
Conclusion
In conclusion, semaglutide is a promising option for individuals looking to lose weight and improve their overall health. The medication has been shown to be effective for weight loss in clinical trials and offers a convenient once-weekly dosing regimen. However, it is important to consider the potential risks and drawbacks of using semaglutide, including side effects and cost. By working closely with a healthcare provider and making lifestyle changes to support weight loss efforts, individuals can make an informed decision about whether semaglutide is the right choice for them.
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With the increasing popularity of GLP-1 use for weight loss, I want to share some critical advice. First & foremost, I don’t believe GLP-1s are for everyone, but those that use this tool shouldn’t be ashamed to ask for help because there cannot be one without the other, you must make take the proper steps to change your lifestyle. And I see many ppl struggling Without support. GLP1s can free up space in your brain. The food noise quiets & the scale finally moving. They can also come with side effects - nausea, slowed digestion and fatigue. Here are the 4 things I would not do if I were on a GLP1 for weight loss. 1. Eat processed or “fast” food. The way these drugs work is to keep your blood sugar from spiking. When you eat foods that are high in sugar or chemicals your body wants these foods out- by any means necessary. It is imperative that you eat a diet high in whole food nutrition. Nothing fried, fast or fatty. 2. Guess my protein intake. When it comes to hitting your protein goal, this should be your #1 priority. As with all extreme calorie restriction, you can easily lose weight in muscle. You need to keep your protein intake up so your body is ridding itself of fat, not muscle. 3. Skip my strength training workouts. Speaking of lean muscle mass, strength training is the best thing women can do for longevity & our metabolism. Not only will your strength grow, but lean muscle mass is what burns up stored fat! 4. Try to go about this alone. Many people think GLPs are a miracle- & maybe for some they are, but you still need guidance & accountability to build healthy sustainable habits. I don’t want you sick- I want you healthy, educated and empowerd! Comment ME below or message me the word “SHOT” and let me show you how!
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