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In this episode, we dive into GLP-1 and its role in weight management, we discussed Lyle McDonald's book The GLP-1 Solution. We discuss the science behind GLP-1 agonists, pharmaceutical industry influence, FDA approval hurdles, and practical lifestyle strategies like balancing food intake, increasing activity, and incorporating resistance training. Whether you're curious about GLP-1 medications or looking for sustainable weight loss strategies, this conversation covers it all! Timestamps: 0:00 - Intro 1:21 - What sparked your interest in GLP? 10:20 - The role of pharmaceutical companies in GLP drug development 23:12 - Balancing increased food intake with more activity 49:12 - The FDA approval process for pharmaceutical companies 1:17:00 - The importance of resistance training at least three times a week 1:30:41 - Closing Amazon book link https://www.amazon.com/dp/B0DT26F7HY Page with entirety of chapter 2 https://theglp1solutionbook.com/chapter-2-glp1-solution/ ⚠️LIKE & SUSCRIBE , COMMENT WHAT PART YOU FOUND MOST INTERESTING FROM TODAY'S VIDEO⚠️ ✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴✴ THINGS YOU DONT WANNA MISS⬇️ I have written a BOOK that covers the Psychology of eating to finally master long lasting results. 🗯https://bit.ly/Astrid_EBOOK ✔Want to become personal trainer? or learn more about the SCIENCE of NUTRITION, CONTEST PREP? PHYSIQUE ACADEMY by Layne Norton & Bill Campbell? Check out all the amazing courses, guidebook & certifications at Clean Health Fitness Institute here 👉https://cleanhealth.edu.au/?ref=astridnaranjo (Code naranjo10  for 10% discount at the checkout) ✔Are you looking for discounted Evidence-based SUPPLEMENTS? I partnered up with LEGION ATHLETICS, cause as a Dietitian I have struggled to find a company I trust & that I could recommend with confidence. Their products are AMAZING. 👉https://legionathletics.rfrl.co/28jv8 👉Use my code AstridRD if you want to support me (20% off for new customers - Double loyalty points for returning customers)  ✔My go to RESEARCH review MASS & Weightology https://transactions.sendowl.com/stores/6865/220955 http://tiny.cc/astridnarRD 🤗⁣A bit about me: I am an accredited practicing dietitian My Key Areas i am passionate about: Weight loss & body re-composition Nutrition Research & nutrition coaching/education Diabetes education & Clinical nutrition Fitness & sports Nutrition Binge eating disorder &Food freedom Women’s health & PCOS Check my website https://astrid-dietitian.com/ 👉Follow me on instagram https://www.instagram.com/antidiet_dietitian/ @astrid.thefitdietitian ( English) Follow me on Tiktok:  https://vm.tiktok.com/JM1npou/ 👉check my website Astrid-dietitian.com 👉Apply for coaching:  https://astridnaranjo.typeform.com/to/rJbJqM

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340 Pounds Down with Zepbound! Jamie Tells the Truth About GLP-1s Downsized Dish with Jamie Selzler – How He Lost 340 Pounds on Zepbound In this episode of The Downsized Dish, Christopher Durham sits down with Selzler, who shares how he lost 340 pounds using the GLP-1 medication Zepbound. Jamie opens up about his experience starting at 652 pounds, the emotional and physical toll of living with severe obesity, and the mindset that helped him transform his life. Filmed in Annapolis, Virginia, during the Your Weight Matters National Convention hosted by the Obesity Action Coalition, this is one of the most honest and inspiring conversations we’ve had. Jamie talks about how he started his GLP-1 treatment with Wegovy, transitioned to Zepbound due to shortages, and has stayed on the medication for nearly two years. Christopher and Jamie cover everything from food noise, and self-discipline to the toxic expectations of diet culture. Jamie explains why exercise wasn't possible at first and how he slowly rebuilt mobility over time. He also shares how he’s shifted his focus from goal weight to input goals like hydration, movement, and consistency. Topics include: • Why it took three months to see results on GLP-1 medication • What to expect with side effects like constipation, fatigue, and food sensitivity • How to keep promises to yourself and build momentum • The power of non-scale victories • Why motivation fades and consistency matters more • Jamie’s plan to hike 20 miles by the end of the year This is a must-watch for anyone treating obesity with GLP-1s or thinking about starting. Jamie brings clarity, encouragement, and practical advice for real people facing real struggles. Follow Jamie on social media and reach out if you need support. His message is simple and powerful: You are not alone, and you deserve a better life. FOLLOW JAMIE: YOUTUBE: @jselzler TikTok:⁠ ⁠@jamselz⁠⁠ IG:⁠ ⁠@jselzler⁠⁠ DOWNSIZED LINKS: Shop our GLP-1 companion products: https://thedownsized.org/downsized-store Visit our website: https://thedownsized.org/ Join us for the Downsized at Sea Cruise 2026: https://thedownsized.org/downsized-at-sea-2026/ Become a channel member and unlock exclusive perks: https://www.youtube.com/@thedownsized/join For sponsorships, brand deals, and press inquiries: https://thedownsized.org/contact/ 00:00 Introduction and Welcome 00:11 Meet Jamie: A Special Guest 00:45 Disclaimer and Social Media Plugs 01:50 Jamie's Weight Loss Journey 02:08 The Role of GLP-1 Medication 02:30 Challenges and Public Speaking 03:04 Mind Pump Podcast Appearance 04:56 Life Changes and Non-Scale Victories 11:33 Exercise and Mobility 17:53 Mindset and Motivation 27:48 Setting Achievable Input Goals 30:52 The Importance of Self-Compassion 32:43 The Journey to Weight Loss 35:07 The Role of GLP-1 Medication 37:04 Managing Side Effects 40:24 Personal Experiences and Advice 42:56 The Emotional Impact of Weight Loss 48:59 Future Goals and Reflections 52:32 Final Thoughts and Encouragement

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Weight loss is a common goal for many individuals, whether it be for health reasons, aesthetic purposes, or both. While there are various methods and strategies to achieve weight loss, one particular drug that has been gaining attention for its effectiveness is semaglutide. Semaglutide is a medication primarily used to treat type 2 diabetes, but it has also been found to be remarkably effective in promoting weight loss.

Understanding Semaglutide

Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. GLP-1 is a hormone that is naturally produced in the body and plays a key role in regulating blood sugar levels and appetite. By mimicking the effects of GLP-1, semaglutide helps to lower blood sugar levels, increase insulin production, and reduce appetite, ultimately leading to weight loss.

One of the key mechanisms by which semaglutide causes weight loss is by slowing down the rate at which food moves through the stomach and small intestine. This delays the emptying of the stomach, leading to a feeling of fullness and satiety that lasts longer after meals. As a result, individuals taking semaglutide tend to eat less, consume fewer calories, and lose weight.

In addition to reducing appetite and food intake, semaglutide also has a direct impact on the brain’s reward system. Studies have shown that semaglutide can alter the brain’s response to food cues and reduce cravings for high-calorie, unhealthy foods. This helps individuals make healthier food choices and further contributes to weight loss.

The Effects of Semaglutide on Weight Loss

Clinical trials have demonstrated the significant weight loss potential of semaglutide. In a study published in the New England Journal of Medicine, researchers found that individuals who took a higher dose of semaglutide (2.4 mg) lost an average of 15% of their body weight over a 68-week period. This was compared to a placebo group, which only lost 2.4% of their body weight.

Aside from promoting weight loss, semaglutide has also been shown to have a number of other health benefits. These include improvements in glycemic control, blood pressure, cholesterol levels, and cardiovascular risk factors. As a result, semaglutide not only helps individuals achieve their weight loss goals but also contributes to overall health and well-being.

It is important to note that semaglutide is not a magic pill for weight loss and should be used in conjunction with a healthy diet and regular exercise. Additionally, like any medication, semaglutide may cause side effects such as nausea, vomiting, and diarrhea. It is essential to speak with a healthcare provider before starting a semaglutide regimen to ensure it is safe and appropriate for individual needs.

FAQs about Semaglutide and Weight Loss

1. How long does it take to see results with semaglutide?

While individual results may vary, many people start to see weight loss within the first few weeks of starting semaglutide. For optimal results, it is recommended to take semaglutide consistently as prescribed by a healthcare provider.

2. Is semaglutide safe for long-term use?

Semaglutide has been shown to be safe and effective for long-term use in clinical trials. However, it is essential to monitor for any potential side effects and regularly follow up with a healthcare provider to ensure its continued safety and efficacy.

3. Can semaglutide be used for weight loss in individuals without diabetes?

While semaglutide is currently approved for the treatment of type 2 diabetes, some healthcare providers may prescribe it off-label for weight loss in individuals without diabetes. It is important to discuss this option with a healthcare provider to determine if semaglutide is suitable for individual needs.





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Since last year, the ketogenic diet has been hugely popular as thousands of health-conscious foodies seek out ways to enter the highly über-online dietary state known as ketosis. At first, lots of us had to totally change the ways eat in order to enlist ketosis and harness its various reputed advantages. To promote weight-loss, boost energy levels, increase brainpower and even potentially treat certain serious illnesses including epilepsy, many of us removed grains and carbs from our diet and replaced them with more animal fat and veggies. Before long, keto diet pills emerged, promising all the keto diet’s benefits without the need for dietary keggs with feet. In other words, with proper supplementation, you won’t have to skimp on grains or even change your diet much at all!

Keto Diet Pills: The Shark Tank Connection

A popular supply of keto diet pills is the TV show Shark Tank, where entrepreneurs pitch their businesses before a panel of investors hoping to get them to buy equity in their products. Several keto diet pill makers have been on the show, promising that their pills will help users reach ketosis in a much faster and more efficient manner. But do they work, and should you give them a try?

However, this excerpt attempts to take a hard look at whether keto diet pills work for those who saw them on Shark Tank, by examining the generally agreed-upon ingredients of most keto diet pills. The majority of keto diet pills contain exogenous ketones (keto-types made outside the body), and those exogenous ketone sources seem mostly to comprise beta-hydroxybutyrate (BHB). BHB is now considered the most effective lifestyle ketone body (also referred to as exogenous ketones) since it’s extremely efficient at fuelling brain and muscle function when one consumes the least amount of carbohydrates.Boost Your Health With Apple Cider Vinegar Gummies Applecidervinegargummies

Understanding the Science Behind Ketosis

As the body starts to lack carbs and all the glucose associated with them, it transitions to fat-burning mode, a process called ketosis. In this state, the body burns ketones for fuel instead of glucose. Ketosis is linked to several benefits, including quick weight loss and improvements in metabolic health, which likely explains why many people would rather switch to keto than submit to calorie-tracking apps and extra cardio. Keto diet pills either stimulate ketosis by increasing ketone production or provide exogenous ketones to spark the very same process.

Although these supplements may not be a magic pill to scale the weigh scale and feel energised, the effectiveness of most keto diet pills depends on food habits, physical activity, and other health parameters. Many keto diet pills are not without side effects as they contain caffeine to suppress appetite and boost alertness and energy. They may cause headaches, gastrointestinal issues, and fatigue. You should always consult a doctor before taking keto diet pills. Whether pills are safe for those without medical issues remains a point open to discussion. The lifestyle changes essential to keto regulation are often difficult to follow and certainly not endorsed by many healthcare providers.

Real-World Results and User Testimonials

Despite mixed reviews and concerns about the effectiveness of the keto diet pills promoted on Shark Tank, quite a few users have reported that they had great results after adding these extra supplements to their daily routine. Some consumers have claimed to see noticeable weight loss, spike in energy level, and a boost in their mental cognitive abilities. Of course, this is not the case for everyone, since different bodies react to external stimuli differently. Make sure to conduct extensive research and read some user testimonials before you make your purchase. It’d also be best if you discuss your decision with your healthcare provider to find out if the keto diet pills are right for you.

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