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We know they are expensive, but isn’t the cost recouped by the healthcare savings? Dr F. Perry Wilson explains. https://www.medscape.com/viewarticle/glp-1s-are-crazy-effective-just-not-cost-effective-2025a10006es?src=soc_yt --TRANSCRIPT-- Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I’m Dr F. Perry Wilson from the Yale School of Medicine. Much of my time in these videos is spent talking about whether a drug or supplement or diet or intervention works or not. That’s the central focus of medical science: Can we do something for a patient and make a difference in their health? But there’s a related question that we rarely discuss that is almost equally as important: Is this drug or supplement or diet or intervention worth it? And I don’t mean “worth it” in some meta-physical sense. I mean "worth it" in terms of dollars and cents. Is the cost we pay for something worth the benefit we derive from it? I’ll make the argument that the most effective drugs in the past decade are the GLP-1 receptor agonists, drugs like semaglutide and tirzepatide. At least in terms of weight loss, they are truly unparalleled. They are clearly effective. But are they worth it? Are they cost-effective? That is a much harder question, and, as you’ll see in a minute, despite their amazing effects, the answer — for now, at least — is no. How do we decide if a drug is cost-effective? What does that even mean? I’ll give you some extreme examples to illustrate the point a bit. First, for it even to be possible that a drug is cost-effective, it must be effective. It must improve health in some clear, measurable way. Pink jelly beans, while quite inexpensive, do not improve health at all and are therefore not cost-effective. Policymakers should not advocate that insurers cover pink jelly beans. On the flip side are drugs and interventions that actually make money for the system — things that are so good for you, they save money in the long term. The childhood vaccination program is probably the best example of this. The CDC estimates that for every $1 spent on the program, the payer saves about $3 in future costs and society saves about $10 in future costs. This is why insurers have no problem covering childhood vaccines; they would literally be leaving money on the table if they didn’t. So those are the extremes. Don’t pay for pink jelly beans, do pay for vaccines. But we don’t think it is appropriate to cover only stuff that saves money. We are willing to trade money for longer life or quality of life. And this is where the rubber meets the road when it comes to cost-effectiveness analysis: How much is your life worth? To an economist, the answer is basically $100,000 per year of perfect health. The ways they arrive at this number are pretty fascinating, but a lot of it is done by looking at what we as a society are willing to pay for. A cost of $100,000 per “quality-adjusted life year” (QALY) is our standard candle here. More than that is not particularly cost-effective. Less than that is. The “quality” in the QALY is important too. Economists know that a year of perfect health is worth more, in dollar terms, than a year of moderate or poor health. So, if we take an intervention and do some clever modeling based on the price of the intervention and its effectiveness at improving health, we can tell you how much it costs per QALY. Here are a few examples. We have an intervention to pay people to quit smoking. This costs about $2500 per QALY. Seems pretty good. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/glp-1s-are-crazy-effective-just-not-cost-effective-2025a10006es?src=soc_yt

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Exploring Low-Carb Dining

Eating out can be a challenge for those following a keto diet, as many traditional dining options center around high-carb foods. However, the rise of health-conscious eating has led to a surge in the number of restaurants offering keto-friendly menus. In a keto diet, the emphasis is on consuming high fats, moderate proteins, and minimizing carbohydrates. This nutritional approach helps the body enter a state of ketosis, where it burns fat for fuel instead of carbohydrates. Finding restaurants that cater to this diet can be daunting, especially when you wish to enjoy a meal with family or friends who may not be following the same dietary restrictions. Thankfully, many establishments now recognize the growing demand for low-carb options and have tailored menus to accommodate those who are on a keto journey.

The increase in awareness of low-carb diets has resulted in remarkable changes in the culinary landscape. Many chefs are experimenting with keto-friendly ingredients, thus creating unique and delightful dining experiences. From gourmet burger joints that offer lettuce wraps instead of buns to upscale restaurants featuring creative ways to incorporate healthy fats, the options are expanding. When looking for the best keto restaurants near you, it is essential to consider several factors, including the variety on the menu, the quality of ingredients, and the overall dining atmosphere. It’s also helpful to focus on establishments that prioritize freshness and have a commitment to health in their food preparation practices.

In this guide, we will explore ten exceptional dining options that are perfect for anyone seeking delicious low-carb meals. Whether you are a dedicated keto dieter or simply someone who values healthier choices in dining, there’s something for you on this list. We will provide insights into the types of dishes you can expect, the ambiance of each restaurant, and tips to maximize your dining experience while sticking to your dietary goals. So, if you’re wondering where to grab a keto-friendly meal in your area, this guide will serve as your comprehensive resource, helping you discover places that align with your low-carb lifestyle.

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A Cozy Café for Keto Mornings

Starting your day with a hearty breakfast while adhering to a keto diet can sometimes feel impossible. However, a cozy café near you may just hold the key to satisfying your breakfast cravings without derailing your dietary preferences. This café offers a diverse range of breakfast items that cater to keto enthusiasts, ensuring you can enjoy your morning meal without the worry of exceeding your carb limits. The menu typically includes options such as avocado toast on keto-friendly bread, scrambled eggs with cheese and bacon, and a variety of omelets loaded with greens and meats.

The café’s ambiance is designed to welcome guests with a warm, inviting atmosphere filled with natural light and charming decor. The staff is often well-informed about dietary needs and is more than willing to provide recommendations for keto-friendly items. Whether you’re on the go or looking to unwind with a leisurely breakfast, this spot prides itself on quality service and fresh ingredients, making it a perfect choice for starting your day right.

For those who appreciate a strong cup of coffee alongside their breakfast, this café doesn’t disappoint. They offer a selection of low-carb coffee options, including bulletproof coffee with grass-fed butter and MCT oil, which serves as an excellent way to boost energy without the carbs. The combination of delicious food and quality beverages creates a delightful experience that aligns with your keto lifestyle, ensuring that you can enjoy breakfast just as much as anyone else, if not more.

An Upscale Dining Experience

If you’re looking for a more refined dining experience that still respects your keto diet, an upscale restaurant with a focus on farm-to-table ingredients is an ideal option. These establishments typically emphasize local sourcing, seasonal ingredients, and culinary creativity. The menu here usually features a variety of meat and seafood options, prepared in ways that accentuate flavors while limiting carbohydrates. With delectable dishes such as seared salmon with cauliflower puree and herb-infused butter or steak accompanied by sautéed Swiss chard, satisfying your palate while staying in ketosis is a true delight.

This upscale setting allows diners to experience exceptional service in a beautifully designed ambiance, often complete with artistic presentations of each dish. The staff typically consist of knowledgeable servers who can guide you through the menu, making personalized recommendations to accommodate your dietary preferences while ensuring a memorable dining experience. Furthermore, many upscale restaurants now cater to various dietary needs, recognizing the importance of providing options to every guest.

The beverage selection at these restaurants is also thoughtfully curated, allowing you to pair your meal with keto-friendly choices. From fine wines that have lower sugar content to creative cocktails made with sparkling water and fresh herbs, the options are plentiful. Dinning at an upscale restaurant means that you can enjoy a night out, socialize, and indulge in gourmet cuisine, all while adhering to your low-carb requirements. It’s about the experience as much as it is about the food, and places like these elevate the enjoyment that comes with dining out on a keto diet.

Burgers Without the Buns

Burgers are a quintessential American meal, but traditional buns are often packed with carbs that are not ideal for those on a keto diet. Fortunately, there are burger joints that cater specifically to low-carb enthusiasts by providing creative alternatives to the conventional burger. Many of these establishments offer lettuce wraps, which serve as a fresh and crunchy substitute for bread, effectively allowing you to indulge in your favorite burger without the carbs. Toppings such as cheese, bacon, avocado, and a variety of sauces can still be enjoyed liberally, ensuring that flavor isn’t sacrificed.

The casual vibe of these burger places makes them an excellent choice for families or a meal with friends. The menu typically highlights a range of protein options, including beef, chicken, turkey, and even plant-based patties for those looking for alternatives. With each burger containing mouthwatering flavors and quality ingredients, it’s easy to forget that you’re dining on a low-carb meal. Plus, many burger joints offer the option to customize your order, allowing you to build your perfect keto burger that fits your taste.

Ambiance is another appealing factor of burger establishments that cater to keto dieters. Often decorated with playful themes, they create an environment that makes you feel right at home while enjoying your food. Many also feature outdoor seating, great for enjoying your meal in the sunshine. By emphasizing the joy of casual dining, these burger joints prove that sticking to a low-carb diet need not take the fun out of eating out. Overall, if you’re craving a delicious burger without the bun, seeking out dedicated burger spots is a fantastic way to satisfy your cravings.

Delicious Deli Choices

When it comes to finding healthy and quick meal options, delis can be a lifesaver for those on a keto diet. Many modern delis have revamped their menus to feature an assortment of low-carb meals. This includes everything from salads loaded with proteins and healthy fats to sandwich options that use low-carb bread or lettuce wraps. Signature dishes at these delis might include roast beef or turkey salads topped with avocado and olive oil dressing, which provide both taste and nutritional benefits.

The deli experience is typically fast-paced, allowing you to grab a meal on the go without compromising your dietary goals. The casual atmosphere is comforting, often filled with the vibrant energy of customers enjoying their meals. With so many customizable options available, you can pick and choose your ingredients, ensuring that every dish meets your keto requirements. Furthermore, the availability of various deli meats means that it is easy to lean on proteins that are satisfying and filling while remaining low in carbs.

In addition to main dishes, many delis offer delicious sides that can complement your meal without packing in excess carbs. Items like pickles, olives, cheese platters, or roasted vegetables are common and make great additions to enhance your dining experience. This versatility allows you to mix and match meals that satiate your hunger while adhering strictly to your Keto diet. For anyone looking for quick yet nutritious options, these modern delis serve as a fantastic choice for delicious low-carb meals.

Asian Cuisine with a Keto Twist

When it comes to dining out, Asian cuisine often gets overlooked by those following a ketogenic diet due to the prevalence of rice and noodles. However, many Asian restaurants offer delectable low-carb alternatives that can satisfy your cravings while adhering to your dietary restrictions. Innovative chefs are starting to craft menus that showcase the rich flavors of Asian cooking with a focus on ingredients that fit the keto lifestyle. Dishes such as cauliflower fried rice, zucchini noodle ramen, and stir-fry with vegetables and meats offer diverse and satisfying options.

The richness of Asian cuisine lies in its spices and sauces, many of which can be made keto-friendly with a few simple adjustments. Many restaurants are willing to modify dishes to accommodate dietary needs, making it crucial to communicate your preferences to the staff. Enjoying a meal that bursts with flavor while also meeting your nutritional goals allows you to experience the best of both worlds in a delightful manner. This makes dining out versatile and enjoyable for those on a keto journey.

The atmosphere of Asian restaurants often exudes tranquility, making them ideal locations for dining experiences filled with shared plates and family-style meals. A focus on communal dining can offer a unique opportunity to explore different flavors and colors within low-carb options, making meals memorable. Plus, the ability to enjoy a combination of ingredients, flavors, and textures allows for a satisfying dining experience that is both culturally rich and health-conscious. Restaurants offering keto adaptations of traditional Asian dishes are not just meals, but rather experiences that highlight a beautiful blend of food culture and dietary mindfulness.

Common Questions About Keto Dining

When exploring the realm of keto-friendly dining, many questions may arise for both novices and seasoned dieters alike. One common question is whether it is possible to eat out while on a strict keto diet. The answer is a resounding “yes.” Many restaurants now cater specifically to low-carb diets, offering a variety of options that allow you to enjoy delicious meals without ruining your diet. The key is to research restaurants that understand keto and can accommodate your dietary needs.

Another frequent inquiry revolves around how to navigate menus successfully. When eating out, it’s advisable to look for items that emphasize proteins and healthy fats while steering clear of high-carb sides or sauces. Opting for ingredients like leafy greens, meats, and healthy oils can help you maintain your keto lifestyle while enjoying a meal with friends or family. Additionally, don’t hesitate to inquire about modifications, as many chefs are willing to adapt dishes for dietary preferences.

Finally, diners often wonder about the social aspect of dining out. It’s essential to remember that dining out with loved ones is ultimately about enjoying time together, regardless of dietary choices. By choosing restaurants that respect your dietary needs and being open to navigating menu options, you can make the experience enjoyable and fulfilling. With the growing popularity of keto diets, the dining scene has evolved to be more accommodating, allowing everyone to dine out with confidence, style, and satisfaction.