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CLICK “MORE” BELOW TO VIEW SELECTED IMPORTANT SAFETY INFORMATION, INCLUDING BOXED WARNING, AND FOR LINK TO PRESCRIBING INFORMATION. Intended for US Health Care Professionals. Please see Important Safety Information at https://bit.ly/47oPfNn. Please see Prescribing Information, including Boxed Warning, at https://bit.ly/3S7sdX0. Selected Important Safety Information —————————————————————— WARNING: RISK OF THYROID C-CELL TUMORS • In rodents, semaglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. It is unknown whether Wegovy® causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of semaglutide-induced rodent thyroid C-cell tumors has not been determined • Wegovy® is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Counsel patients regarding the potential risk for MTC with the use of Wegovy® and inform them of symptoms of thyroid tumors (e.g. a mass in the neck, dysphagia, dyspnea, persistent hoarseness). Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with Wegovy® —————————————————————— Indications and Usage Wegovy® (semaglutide) injection 2.4 mg is indicated in combination with a reduced calorie diet and increased physical activity: • to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established cardiovascular disease and either obesity or overweight • to reduce excess body weight and maintain weight reduction long term in adults and pediatric patients aged 12 years and older with obesity and adults with overweight in the presence of at least one weight-related comorbidity Limitations of Use: Wegovy® contains semaglutide. Coadministration with other semaglutide-containing products or with any GLP-1 receptor agonist is not recommended Important Safety Information (cont'd) Contraindications • Wegovy® is contraindicated in patients with a personal or family history of MTC or in patients with MEN 2, and in patients with a prior serious hypersensitivity reaction to semaglutide or to any of the excipients in Wegovy®. Serious hypersensitivity reactions, including anaphylaxis and angioedema have been reported with Wegovy® Warnings and Precautions • Risk of Thyroid C-Cell Tumors: Patients should be further evaluated if serum calcitonin is measured and found to be elevated or thyroid nodules are noted on physical examination or neck imaging • Acute Pancreatitis: Acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, has been observed in patients treated with GLP-1 receptor agonists, including Wegovy®. Observe patients carefully for signs and symptoms of acute pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back, and which may or may not be accompanied by vomiting). If acute pancreatitis is suspected, discontinue Wegovy® and initiate appropriate management • Acute Gallbladder Disease: Treatment with Wegovy® is associated with an increased occurrence of cholelithiasis and cholecystitis. The incidence of cholelithiasis and cholecystitis was higher in Wegovy® pediatric patients aged 12 years and older than in Wegovy® adults. In clinical trials in adult patients, cholelithiasis was reported by 1.6% of Wegovy® patients and 0.7% of placebo patients. Cholecystitis was reported by 0.6% of Wegovy® patients and 0.2% of placebo patients. In a clinical trial in pediatric patients aged 12 years and older, cholelithiasis was reported by 3.8% of Wegovy® patients and 0% placebo patients. Cholecystitis was reported by 0.8% of Wegovy® pediatric patients and 0% placebo patients. Substantial or rapid weight loss can increase the risk of cholelithiasis; however, the incidence of acute gallbladder disease was greater in Wegovy® patients than in placebo patients, even after accounting for the degree of weight loss. If cholelithiasis is suspected, gallbladder studies and appropriate clinical follow-up are indicated See additional Warnings and Precautions and Important Safety Information here: https://bit.ly/47oPfNn. Wegovy® is a registered trademark of Novo Nordisk A/S. Novo Nordisk is a registered trademark of Novo Nordisk A/S. © 2025 Novo Nordisk All rights reserved. US25SEMO00201 April 2025

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Today, I want to talk about plastic surgery after weight loss through GLP-1 medications like Ozempic. For the past 20 years, I’ve been helping patients who’ve lost significant weight, whether through gastric bypass or other surgeries, and in recent years, we’ve seen a rise in patients losing weight with GLP-1 medications. While the weight loss process is similar, I've noticed that patients on Ozempic tend to lose more skeletal muscle compared to those who underwent traditional weight loss surgery. This results in issues like "Ozempic face," which requires facial rejuvenation, and skin laxity or "Ozempic body" in areas like the arms, abdomen, and thighs, often needing a lift. For those with buttock deflation, both fatty tissue and skeletal muscle loss, buttock augmentation and reshaping are necessary. Overall, the outcomes from weight loss surgeries and Ozempic are quite similar, but in some cases, additional skeletal mass augmentation, like in the buttocks, is needed for optimal results. #drsiamakagha #newportbeachplasticsurgery #thighreduction #lowerbodylift #skinlaxity #looseskin #skinremovalsurgery #bodyliftsurgery #wls #weightlosssurgery #weightloss #ozempic #mounjaro #boardcertifiedplasticsurgeon #semaglutide #Bariatric #vsg #glp1 #glp1weightloss #glp1community

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A new White House proposal would make Medicare and Medicaid cover costly weight loss drugs for people who are obese. CBS' Erica Brown reports from Washington, DC.

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A deep dive into the science and the effects - good and bad - of the controversial drug Ozempic and other weight loss injection ► WATCH Full Episodes on 9NOW: https://9now.app.link/uNP4qBkmN6 ► Subscribe here: http://9Soci.al/chmP50wA97J *Synopsis | Reshaping the World (2024)* Blame it on our success as a wealthy western nation, but we live with an enormous problem. Our size. Too many Australians are too big. Everyone knows excess weight is bad for our health, but battling the bulge is a fight too few of us win. And that’s the reason drugs like Ozempic are in such demand. They promise a quick fix to losing kilos, even though they’re not designed as weight-loss remedies. But as Dimity Clancey reports, users need to be very cautious. The Ozempic hype is starting to wither, replaced with the reality that it and similar drugs are risky, even deadly. *MORE VIDEOS like this one* ► https://www.youtube.com/watch?v=3nvoumJsjus ► https://www.youtube.com/watch?v=2l25ixKvYtk ► https://www.youtube.com/watch?v=SvQGfwYIOA0 FOLLOW 60 Minutes Australia ► WATCH more of 60 Minutes Australia: https://www.60minutes.com.au ► Facebook: https://www.facebook.com/60Minutes9 ► Twitter: https://twitter.com/60Mins ► Instagram: https://www.instagram.com/60minutes9 ABOUT 60 Minutes Australia For over forty years, 60 Minutes Australia have been telling Australians the world’s greatest stories. Tales that changed history, our nation and our lives. Reporters Liz Hayes, Tara Brown, Amelia Adams, Adam Hegarty, Dimity Clancey and Nick McKenzie look past the headlines because there is always a bigger picture. Sundays are for 60 Minutes Australia. #60MinutesAustralia