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This video is also available in ENGLISH Determination of Moisture Content By Loss on Drying Method (English) https://youtu.be/YP7Sai2BbZQ Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/details?id=co.bolton.nqilv MOISTURE DETERMINATION Every crude drug contains some moisture in it, so it is very important to determine the percent of moisture inside it. there are several methods to determine it but the loss on drying is an easy and effective technique. Moisture content determination is one of the important parameters for quality evaluation of crude drug and crude extract. The presence of excess moisture favors the growth of the microorganism and deteriorates the crude drug. So moisture content should be within a specified limit which is acceptable. To perform loss on drying experiments we have to weigh the crucible in an empty state and then measure 0.50 gm of the crude drug than allow it to dry in 100-105 degree for about 15 mint. than place it in a desiccator to cool down and to prevent further moisture absorption and then again place it in the oven till constant weight is received. now finally calculate the moisture content by using the given formula in the video. Procedure: (Drying in Oven): Loss on drying is loss of weight expressed as % w/w resulting from the water and volatile matter of any kind that can be driven off under specified condition.This test is carried out on a well-mixed sample of the substance. If the substance is in the form of large crystals, reduce the size by rapid crushing to a powder. 1. Weigh a glass stoppered, shallow weighing bottle (W1) that has been dried under the same conditions to be employed in determination. 2. Transfer to the bottle the quantity of the sample specified in the individual monograph. Cover it and accurately weigh the bottle and the contents (W2). 3. Distribute the sample as evenly as practicable by gentle sidewise shaking to a depth not exceeding 10 mm. 4. Place the loaded bottle in drying chamber as directed in the monograph per and leave it also in the chamber. Dry the sample to constant weigh or for the specified time and at the temperature indicated in the monograph. 5. After drying is completed, open the drying chamber, close the bottle promptly and allow it to cool to room temperature (where applicable) in a desiccator before weighing. Weighing bottle and contents(W3). 6. When “dry to constant weight” is specified in a monograph, drying shall be continued until two consecutive weighings (W4) do not differ by more than 0.50 mg per g of substance taken, the second weighing following an additional hour of drying. Upon opening the chamber, close the bottle promptly, and allow it to come to room temperature in a desiccator before weighing. Get in touch with the solution by just clicking following links- Facebook Group- https://www.facebook.com/groups/solutionpharamcy Facebook Page- https://www.facebook.com/pharmavideo/ New channel (Pharmacy Dictionary) - https://www.youtube.com/channel/UCt6OXVV_2oxf5DD0Mad6e9A Instagram- https://www.instagram.com/solutionpharmacy/ E-Mail for official and other work - [email protected] LinkedIn- http://linkedin.com/in/pushpendrakpatel #solutionpharmacy #Pharmacologyclass #GPATonlinetest
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Semaglutide has been making waves in the weight loss industry as a promising drug that can help individuals shed excess pounds. This injectable medication works by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1), which helps to regulate blood sugar levels and decrease appetite. When used in conjunction with diet and exercise, semaglutide has been shown to produce significant weight loss results.
Choosing the Best Injection Site
One of the key factors in maximizing the efficacy of semaglutide for weight loss is choosing the right injection site. While semaglutide can be injected into various areas of the body, there are certain locations that may yield better results than others. Here are some tips for selecting the best place to inject semaglutide for optimal weight loss outcomes:
1. Abdomen: Many healthcare professionals recommend injecting semaglutide into the abdomen, as this area typically has a higher concentration of fat tissue. When injecting into the abdomen, it’s important to rotate injection sites to prevent irritation or scarring. Additionally, avoid injecting into scar tissue, stretch marks, or areas with moles or other skin abnormalities.
2. Thigh: The thigh is another common injection site for semaglutide. When injecting into the thigh, aim for the outer area and avoid areas near the knee or groin. Be sure to rotate injection sites to prevent buildup of scar tissue or irritation. Using an alcohol swab to clean the injection site can help reduce the risk of infection.
Tips for Injection Administration
Proper administration of semaglutide injections is crucial for achieving optimal weight loss results. Here are some tips to ensure you are injecting the medication correctly:
1. Follow your healthcare provider’s instructions: Before using semaglutide, make sure you understand how to properly administer the injection. Your healthcare provider should show you how to prepare and inject the medication, as well as provide guidance on proper injection technique.
2. Rotate injection sites: To prevent irritation, scarring, or infection, it’s important to rotate injection sites with each dose. This helps ensure that the medication is being absorbed effectively and reduces the risk of developing lumps or bumps at the injection site.
Managing Side Effects
Like any medication, semaglutide may cause side effects in some individuals. Common side effects of semaglutide include nausea, vomiting, and diarrhea. If you experience severe or persistent side effects, it’s important to contact your healthcare provider for further guidance. Here are some tips for managing side effects while taking semaglutide for weight loss:
1. Stay hydrated: Drinking plenty of water can help alleviate nausea and prevent dehydration. Aim to drink at least eight glasses of water per day to stay hydrated and flush out any toxins from your system.
2. Eat small, frequent meals: To help reduce nausea and vomiting, try eating small, frequent meals throughout the day rather than three large meals. Avoid greasy or spicy foods, as these can exacerbate digestive issues.
Monitoring Your Progress
Tracking your weight loss progress while using semaglutide can help you stay motivated and on track to reaching your goals. Here are some tips for monitoring your progress and making adjustments as needed:
1. Keep a food diary: Recording what you eat can help you identify any patterns or triggers that may be hindering your weight loss efforts. Be sure to include portion sizes, calories, and any snacks or treats you consume throughout the day.
2. Measure your waist circumference: In addition to tracking your weight on the scale, measuring your waist circumference can provide valuable insight into your progress. A reduction in waist size is often a better indicator of fat loss than overall weight loss.
In conclusion, choosing the best place to inject semaglutide for weight loss can help maximize the effectiveness of this medication. By following proper injection techniques, managing side effects, and monitoring your progress, you can achieve optimal results and reach your weight loss goals.
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