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Explore our entire animation video library at: https://www.nonstopneuron.com/ All videos from endocrine pharmacology: https://www.nonstopneuron.com/post/pharmacology-endocrine-system Video Summary: GLP-1 receptor agonists are basically GLP-1 analogs resistant to degradation by DPP-4. They directly stimulate the GLP-1 receptor and cause insulin release. DPP-4 inhibitors, on the other hand, prevent the degradation of endogenous GLP-1. So the effect of GLP-1 on β cells is increased and again, more insulin is released ● More videos on Insulin and Diabetes • Mechanism of Insulin Secretion: https://youtu.be/5M7Lj9Fx1_w • Mechanism of Action of Sulfonylureas and Meglitinide Analogues: https://youtu.be/rz7KJK_EMpA • Oral Antidiabetic Drugs Classification: https://youtu.be/mMRQiaxkyCM ● Follow me at: • Facebook: https://www.facebook.com/NonstopNeuron • Instagram: https://www.instagram.com/NonstopNeuron/ DISCLAIMER: This video is for education purpose only. Although every effort is made to ensure accuracy of material, viewer should refer to the appropriate regulatory body/authorised websites, guidelines and other suitable sources of information as deemed relevant and applicable. In view of possibility of human error or changes in medical science, any person or organization involved in preparation of this work accepts no responsibility for any errors or omissions or results obtained from use of information in this video.

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Semaglutide, a peptide originally developed for the treatment of type 2 diabetes, is gaining attention for its potential as a weight loss medication. The drug works by mimicking the action of a hormone called glucagon-like peptide-1 (GLP-1), which helps regulate blood sugar levels and appetite. Recent studies have shown that semaglutide can lead to significant weight loss in overweight and obese individuals. This article will explore how semaglutide works, its effectiveness for weight loss, potential side effects, and other important information you should know about this promising new treatment.

How Semaglutide Works for Weight Loss

Semaglutide works by activating GLP-1 receptors in the brain, which helps control appetite and food intake. It also slows down the emptying of the stomach, leading to a feeling of fullness and reduced food cravings. In addition, semaglutide may increase the body’s sensitivity to insulin, leading to improved blood sugar control and reduced risk of weight gain. These combined effects make semaglutide an effective treatment for obesity and overweight.

Studies have shown that semaglutide can lead to significant weight loss in overweight and obese individuals. In one study, participants who took semaglutide lost an average of 15% of their body weight, compared to just 2.4% in the placebo group. In another study, participants who took semaglutide lost an average of 17.4% of their body weight, compared to 4.8% in the placebo group. These results demonstrate the powerful weight loss effects of semaglutide.





Potential Side Effects of Semaglutide

Like any medication, semaglutide can cause side effects in some individuals. The most common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild to moderate in intensity and tend to improve over time. In rare cases, semaglutide can also cause more serious side effects, such as pancreatitis or kidney problems. It is important to talk to your doctor about the potential risks and benefits of taking semaglutide for weight loss.

In addition to side effects, there are a few other important things to consider before taking semaglutide for weight loss. For example, semaglutide is not recommended for individuals with a history of pancreatitis, thyroid cancer, or certain other medical conditions. It is also important to follow a healthy diet and exercise regimen while taking semaglutide to maximize its weight loss benefits.

Other Important Information About Semaglutide

Semaglutide is typically taken once a week as a subcutaneous injection. Your doctor will determine the right dose for you based on your individual needs and medical history. It is important to follow your doctor’s instructions carefully and not to adjust your dose without consulting them first. In addition, semaglutide is not currently approved by the FDA for weight loss, but it is available by prescription for the treatment of type 2 diabetes.

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Overall, semaglutide shows great promise as a peptide for weight loss. Its ability to reduce appetite, increase feelings of fullness, and improve metabolic function make it a valuable tool in the fight against obesity and overweight. If you are struggling to lose weight through diet and exercise alone, semaglutide may be a safe and effective option to consider with the guidance of your healthcare provider.

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You may be looking to optimize your appetite suppression, especially with the explosion of all the GLP-1 medications. Although GLP-1 appetite suppression medications aren’t necessarily “new”, they’ve gotten a lot of attention in the last year. They do provide impressive results for many, especially those with a genetic predisposition to appetite dysregulation. But let’s be honest. Not everyone needs appetite suppression. So don’t get confused with the messaging. Just because you may need to lose weight doesn’t mean your appetite needs to be suppressed. Appetite suppression can be helpful when out of balance, but it doesn’t guarantee long-term weight loss success. And losing weight doesn’t guarantee resolution to your health problems. This is where multiple modalities may be necessary to achieve ideal appetite suppression. You see, it may not only require optimizing foods that increase GLP-1 appetite suppression, but medication, nervous system work, lifestyle changes, neurotransmitter enhancement. Because there’s absolutely nothing wrong with staying full and satisfied with your food choices. In fact, it’s just smart. This is how you should eat. Providing your body with nourishing foods that can sustain your health and appetite. Because diet culture has convinced people that you need to be hungry to be successful with weight loss. Where in fact, this is just not true. So, let’s dig into how to eat for optimal GLP-1 appetite suppression:- These include… Yerba Mate` tea Olive oil Protein Fermentable Fiber Descriptions :- -Yerba Mate tea is relatively low in caffeine compared to coffee, but some individuals that are genetically slow caffeine metabolizers would want to use caution. -It shows that an increased intake of olive oil lowers the risk of morbidity and mortality of cardiovascular disease AND increases the release of GLP-1 appetite suppressing hormones. -protein is quite satiating, but studies do show that certain types of protein perform a little better at increasing GLP-1 appetite suppression hormone. -Fermentable Fibers. This is an important piece as this influences your gut bacteria, which play a role in appetite regulation too. As you can see, eating for optimal GLP-1 appetite suppression isn’t rocket science. Although there’s some intentionality required. None of these foods are expensive, hard to find or bad tasting. So the moral of the story is, if you’re looking to improve your appetite suppression. Write down this list. Yerba Mate` tea, EVOO, protein, soluble and resistant starch. There are ENDLESS meal combinations. If you would like to work with me on this issue, feel free to reach out on my website or any social media platform. Check out our Gastric Health Membership: https://gastrichealth.com/product/gastric-health-membership/?v=4096ee8eef7d Take a look at my packages and schedule a FREE consultation: https://gastrichealth.com/product/free-consultation/?v=4096ee8eef7d. Follow our podcast on our website: https://gastrichealth.com/series-the-gastric-health-show/?v=4096ee8eef7d. About Gastric Health: https://gastrichealth.com/about/?v=4096ee8eef7d Get the latest insights and trends about weight loss surgery (WLS) and gut health. Learn the best ways, tips, and tricks in keeping the body in a healthy shape. Follow us on social media. Facebook: https://www.facebook.com/wlsrddawn Instagram: https://www.instagram.com/the_gastric...

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