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Title self-explanatory; this is your comprehensive overview of Tesofensine! Here is a re-upload without background music! Link to the original video with background music: https://www.youtube.com/watch?v=PjifT-nMGbU&t=370s Patreon: https://patreon.com/peptidebuddy Research Articles Enhancement of Cognitive Function by Selegiline - pubmed.ncbi.nlm.nih.gov/19777399/ Noradrenaline, Dopamine, and Serotonin Transporters and their Role in Cognitive Function - pubmed.ncbi.nlm.nih.gov/20200509/ Clinical Study of Neurotransmitter Modulation in Neurological Disorders - pubmed.ncbi.nlm.nih.gov/18356831/ Monoaminergic Pathways in Cognitive Health - pubmed.ncbi.nlm.nih.gov/17324246/ The Role of Neurotransmitters in Obesity - pubmed.ncbi.nlm.nih.gov/20077053/ Monoamine Neurotransmitter Structures - pubmed.ncbi.nlm.nih.gov/11763162/ Monoamine Oxidase Inhibitors in Depression - pubmed.ncbi.nlm.nih.gov/35294397/ Impact of Neurotransmitter Levels on Behavioral Responses - nature.com/articles/npp201016 Neurological and Behavioral Relationships of Neurotransmitters - pmc.ncbi.nlm.nih.gov/articles/PMC11042726/ Supplementary Sources Monoamine Neurotransmitters - sciencedirect.com/topics/neuroscience/monoamine-neurotransmitter Chemical Structure of Monoamine Neurotransmitters - researchgate.net/figure/The-monoamine-neurotransmitters-The-chemical-structure-of-each-of-the-three-monoamine_fig1_283493032 Clinical Trials on Monoamine Modulation - clinicaltrials.gov/study/NCT00148512 Tesofensine Clinical Studies - go.drugbank.com/drugs/DB06156/clinical_trials?conditions=DBCOND0049114&phase=2&purpose=treatment&status=completed GLP-1 Agonist Development for Obesity - boehringer-ingelheim.com/science-innovation/human-health-innovation/clinical-pipeline/survodutide-bi-456906-glp1-gcgr-agonist-obesity Key Developments in Obesity Research - iqvia.com/-/media/iqvia/pdfs/library/articles/obesity-key-pipeline-developments-and-clinical-trial-insights.pdf Overview of Tesofensine Studies - clinicaltrialsarena.com/projects/tesofensine/?cf-view Tesofensine Mechanisms and Effects - sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/tesofensine NeuroSearch's Phase IIb Study Results - globenewswire.com/news-release/2007/09/17/85025/0/en/NeuroSearch-announces-breakthrough-tesofensine-results-from-clinical-Phase-IIb-study-in-obesity-TIPO-1.html Saniona Buys Out NeuroSearch Payment Obligation - biospace.com/saniona-buys-out-payment-obligation-to-neurosearch-a-s Relationship among Noradrenaline, Serotonin, and Dopamine - researchgate.net/figure/Relationship-among-noradrenaline-serotonin-and-dopamine-and-some-behaviors_fig1_26287603 How SSRIs Work - ocduk.org/overcoming-ocd/medication/how-ssri-work/ Pathophysiology in Parkinson's Disease - parkinsonsdisease.net/basics/pathophysiology-what-is-it Antidepressant Discontinuation Syndrome - my.clevelandclinic.org/health/diseases/25218-antidepressant-discontinuation-syndrome #tesofensine #reserach #weightloss #weightlossjourney #peptides #health #antiaging #longevity #biohacking DISCLAIMER: The content provided in this video is for informational and educational purposes only. It is not intended to be, nor should it be considered, medical advice, diagnosis, or treatment. While we strive to present accurate and up-to-date information, the content is based on publicly available research and personal opinions. Medical knowledge is constantly evolving, and new research may affect the validity of the information provided. Always consult a qualified healthcare professional for advice tailored to your individual health needs.
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A major issue with GLP - 1 medications is their cost. Most insurances are not covering these for the treatment of obesity or overweight. Even for many diabetics, the cost is substantial with co-pays and deductibles. The brand drugs can run between $1000 and $2000 dollars monthly. During the time when the major pharmaceutical companies could not produce enough of the drugs to supply the need, the FDA has allowed certified compounding pharmacies to make and dispense the medications. Once the shortage is over, these pharmacies may no longer produce and dispense the medications. This will cause a major disruption in patients receiving these life saving medications. The cost from compounding pharmacies is high but only about 1/3 to 1/2 the cost of the large pharmaceutical companies. These medications can easily be over $1000 monthly. Hopefully, there can be some modification to allow for the less expensive meds to be obtained.
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