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Our GLP-1 Journey: 50 Weeks of Weight Loss and Life Updates In this episode of The Downsized, hosts Laraine and Christopher Durham recount their ongoing journey with GLP-1 medications like compounded Trizepatide, Mounjaro, and Zepbound. Celebrating their 50th week of weight loss, they discuss their experiences, the effectiveness of different medications, and their personal weight updates. The couple also shares recent life events, including their return from a cruise and dealing with the aftermath of Hurricane Helene. They address concerns about medication shortages and emphasize the importance of checking with healthcare providers before starting any weight loss journey. Additionally, they highlight their online resources and invite viewers to join the community, share their stories, and support hurricane relief efforts through the American Red Cross. DONATE TO HELP HURRICAN HELENE VICTIMS: https://www.redcross.org/donate/dr/hurricane-helene.html JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/ join DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store/ Start your weight loss journey today! We use Mochi Health: https://joinmochi.com/. Use Laraine’s code for $40 off: QIYGO8. DOWNSIZED WEBSITE: https://thedownsized.org/ 00:00 Introduction and Welcome 00:12 Our Weight Loss Journey with GLP-1 Medications 01:52 Weekly Weigh-In and Personal Experiences 04:02 Tracking Progress and Tools 04:47 Challenges and Adjustments 09:54 Travel Stories and Health Updates 18:10 Unexpected Hurricane in the Mountains 18:39 Emergency in Raleigh and Boone 19:29 Flooding and Car Troubles 20:57 Football Game Amidst Chaos 21:30 Devastation in Western North Carolina 22:28 Daughter's Safe Return 23:25 Call for Donations and Support 25:20 Reflections on Weight Loss Journey 31:25 The Downside's Dish and Community 36:02 Compounded Medication Concerns 38:25 Closing Remarks and Call to Action
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Best diet for thyroid, best foods to eat in hypothyroid Thyroid ka ilaaj, hypothyroid ka ilaaj -------------------------------------------------------------------------------------------------- Dr Khalid Jamil (Retired) Assistant Prof. Sheikh Zayed Institute Lahore Website: http://khalidjamil.com/ Facebook: https://www.facebook.com/DrKhalidJami... Email: [email protected] --------------------------------------------------------------------------------------------------- Dr Khalid Jamil was an Assistant Professor Urology at Sheikh Zayed Hospital and Kidney Transplant Center, Lahore. In 2003, he was diagnosed with Type 2 Diabetes and High Blood Pressure and was prescribed oral medications, exercise & diet control. In 2016, he was put on insulin due to increase in urea creatinine and retinopathy. The deteriorating health led Dr. Khalid on a quest to find answers. He started intensively studying Type 2 Diabetes, its’ prevention and cure. He consulted doctors but none were able to give answers to his questions. Then finally, he stumbled upon a YouTube video of Dr. Jason Fung, that video proved to be a life changing moment in Dr. Khalid’s life. Dr. Jason Fung is a Canadian nephrologist who claimed 100% cure and reversal of Diabetes via intermittent fasting and some lifestyle changes. A doctor himself, Dr. Khalid extensively studied Jason Fung’s theories. Now, since 2018, he is on a ketogenic diet and doing intermittent fasting with walk and exercise. He is off the medicines now and his creatinine levels are also back to normal. Dr. Khalid is no longer practicing Urology and has instead made it his mission to educate people on social media about what he has learned & practiced so that they are also able to cure 80-90% of all diseases caused by Insulin Resistance. Dr. Khalid is starting weekly lectures on Facebook & Youtube on curing Kidney Problems, Diabetes and Blood Pressure through Ketogenic Diet and intermittent fasting. #bestdietforhypothyroid #drkhalidjamil
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When it comes to weight loss, there are countless strategies and medications available on the market. One medication that has been gaining attention for its potential weight loss benefits is semaglutide. This medication, originally developed to treat type 2 diabetes, has shown promise in helping individuals shed unwanted pounds. But how much weight loss can one expect from taking semaglutide? In this article, we will explore the average weight loss reported in studies on semaglutide.
What is Semaglutide?
Semaglutide is a medication that belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. Originally developed to help control blood sugar levels in individuals with type 2 diabetes, semaglutide has also been found to have potential benefits for weight loss. When taken as a once-weekly injection, semaglutide works by mimicking the effects of a hormone in the body that helps regulate appetite and food intake.
Studies have shown that semaglutide can lead to significant weight loss in individuals who are overweight or obese, making it a promising option for those struggling to lose weight through diet and exercise alone.
It is important to note that semaglutide is not a magic pill for weight loss and should be used in conjunction with a healthy diet and regular physical activity. Additionally, as with any medication, there may be potential side effects and risks associated with taking semaglutide, so it is essential to consult with a healthcare provider before starting treatment with this medication.
Studies on Semaglutide and Weight Loss
Several clinical trials have been conducted to evaluate the effectiveness of semaglutide for weight loss. One of the most well-known studies is the STEP trial, which involved over 4,500 participants who were overweight or obese. The results of this trial showed that individuals who took semaglutide experienced an average weight loss of around 15-20% of their body weight over the course of the study.
Another study published in the New England Journal of Medicine found that individuals who took semaglutide in combination with lifestyle interventions lost an average of 13.8% of their body weight, compared to just 2.3% in the placebo group. These results demonstrate the significant weight loss potential of semaglutide when used as part of a comprehensive weight loss program.
Overall, the studies on semaglutide and weight loss have shown promising results, with participants experiencing substantial reductions in body weight when taking this medication. While individual results may vary, semaglutide appears to be a valuable tool for those looking to achieve meaningful weight loss results.
Potential Side Effects and Considerations
While semaglutide may be effective for weight loss, it is essential to consider potential side effects and other factors before starting treatment with this medication. Some common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. In rare cases, more serious side effects such as pancreatitis or kidney problems may occur.
Additionally, semaglutide is not recommended for individuals with a history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2. It is crucial to discuss any underlying health conditions or concerns with a healthcare provider before starting treatment with semaglutide.
Overall, while semaglutide shows promise as a weight loss medication, it is essential to weigh the potential benefits against the risks and side effects before incorporating it into a weight loss plan. Consulting with a healthcare provider can help determine if semaglutide is the right choice for achieving your weight loss goals.
Conclusion
In conclusion, studies on semaglutide have shown that this medication can lead to significant weight loss in individuals who are overweight or obese. With an average weight loss of around 15-20% of body weight reported in clinical trials, semaglutide appears to be a valuable tool for those looking to achieve meaningful weight loss results.

While semaglutide may have potential side effects and risks, it is essential to consult with a healthcare provider before starting treatment with this medication. By incorporating semaglutide into a comprehensive weight loss program that includes a healthy diet and regular physical activity, individuals may be able to see significant reductions in body weight and improve their overall health and well-being.
Overall, the average weight loss on semaglutide reported in studies highlights the potential of this medication as a promising option for individuals struggling to lose weight. By understanding the benefits and considerations of using semaglutide for weight loss, individuals can make informed decisions about incorporating this medication into their weight loss journey.
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