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Sign up for our Nutrition program! It's available to anyone, anywhere: https://www.poundofcureweightloss.com/nutrition In Episode 41 of the Pound of Cure Weight Loss podcast, we explore the growing use of GLP-1 medications for weight loss, particularly focusing on compounded versions of Semaglutide and Tirzepatide. These medications, typically found in Ozempic, Wegovy, Zepbound, and Mounjaro, have become incredibly popular for their effectiveness in helping patients lose weight. With shortages of these factory-produced drugs, compounding pharmacies have emerged as a more accessible and affordable alternative for many. But what exactly does compounding mean, and is it safe? We break down how compounding pharmacies create custom versions of medications, often offering a lower-cost option. While the appeal is strong, compounded meds come with potential risks. Quality and dosage can vary significantly, raising concerns about safety and effectiveness. We share patient stories and real-world examples of how compounded versions can differ from the original medications in potency and results, and we explain why patients should approach compounded GLP-1 meds with caution. Beyond the legal and safety considerations, we also discuss practical tips for those taking GLP-1 medications for weight loss, such as staying hydrated. These meds not only curb hunger but also reduce the body’s natural thirst response, making it easy to become dehydrated. We offer simple strategies for maintaining hydration while on these medications, which is crucial for overall health and well-being. Finally, we look ahead to the future of compounded medications. As shortages ease and patents become enforceable, compounded versions of GLP-1 drugs may become less common. We also touch on the possibility of generic versions hitting the market, making these life-changing medications more affordable and accessible. If you're considering compounded meds or just want to learn more about your options, this episode offers valuable insights into how to make the best choices for your weight loss journey. Social Media: https://www.facebook.com/APoundofCure https://www.instagram.com/drmatthewweiner/?hl=en https://www.tiktok.com/creator-center/content Books: A Pound of Cure https://www.amazon.com/gp/product/B00AEYQYDE/ https://www.audible.com/pd/A-Pound-of-Cure-Audiobook/B09T777LSW How Weight Loss Surgery Really Works https://www.amazon.com/gp/product/1688128808/ The Bariatric Diet Guide and Cookbook https://www.amazon.com/Bariatric-Diet-Guide-Cookbook-Weight-Loss/dp/1615649875/ 00:00 Disclaimer 00:17 Compounding Teaser Clip 00:39 Introduction 1:18 In the News - Why Millions are Trying Alternatives to Big Pharma's Weight Loss Drugs 11:42 Nutrition Segment - Are you forgetting this important piece of your nutrition while on a GLP-1? 14:11 What is a compounding pharmacy?

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Our full interview with Deborah Evans. We spoke to Deborah Evans about GLP-1 receptor agonists – the fat jabs – and what we have learned over the past 12-18 months. Read, watch and listen here - https://medicalupdateonline.com/2025/03/glp-1-ras-where-are-we-now-what-have-we-learned/?utm_source=youtube&utm_medium=social&utm_campaign=organic Register on our website for news straight to your inbox - https://medicalupdateonline.com/register/ This episode of ‘In Discussion With’ is also on Spotify. Listen to the full podcast now - https://creators.spotify.com/pod/show/medicalupdateonline/episodes/GLP-1-RAs--where-are-we-now--What-have-we-learned-e300s0f 0:00 - Introduction, titles & roles 1:24 - Are GLP-1 RAs easy & safe for weight loss? 3:08 - Differences - semaglutide vs. tirzepatide 6:31 - Side-effects of GLP-1 RAs 8:33 - Serious side-effects of GLP-1 RAs 10:07 - How to get GLP-1 RAs 12:27 - GLP-1 RAs via the NHS 14:54 - Additional support for patients 16:03 - Incorrect GLP-1 RA prescribing 18:02 - Counterfeit GLP-1 RAs 19:37 - Short-term use of GLP-1 RAs? 24:06 - Should you take GLP-1 RAs for life? 25:12 - Risks of sarcopaenia and osteoporosis 28:19 - Dose optimisation 30:34 - Tolerability variations 31:24 - Dose individualisation 33:20 - GLP-1 RA drug switching 35:58 - GLP-1 RA non-responders 37:24 - Starting GLP-1 RAs – what to expect 40:02 - Do we eat too much? 42:39 - Value of GLP-1 RA weight loss 43:56 - Possible anaesthetic risk 46:49 - Outro This interview was recorded on 06/02/2025. ___ Keep up to date with us across our network; Email us at - [email protected] Site - https://medicalupdateonline.com/ Twitter - https://twitter.com/medupdateon1ine Instagram - https://www.instagram.com/medicalupdateonline Facebook - https://www.facebook.com/medupdateonline LinkedIn - https://www.linkedin.com/company/medicalupdateonline This content is for informational purposes only, and does not replace the advice of your own doctor or healthcare professional. Copyright © 2022 MedicalUpdateOnline. IMI (a trading name of ICR UK Limited) is a digital communications agency that specialises in the pharmaceutical and medical industries. IMI was founded in 2003 by the current CEO Peter Mas-Mollinedo, a pharmacist and forward-thinking entrepreneur. IMI’s primary activities include the production of medical educational journals and bulletins, medical conference coverage and video interviewing of health care professionals worldwide to disseminate information such as trial results, new products, research, drug approvals, new accreditations, etc. It is a trusted provider of medical information to its extensive database of medical health care professionals in the UK, Europe and beyond. To find out more about IMI, please see our websites www.medicalupdateonline.com and www.medicalimi.com. Alternatively, you can email us at [email protected].

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Please email Oprah at https://www.oprah.com/plugform.jsp?plugId=220 and tell her about me and our success stories. Tell her about my abiity to inspire, inform, and motivate. Please help me circulate this video. I want to get to Oprah. The reason is that I have a message and a system that will allow people to stand up and take control of their own life through fitness. If you have been trained by me or our a follower please take 2 minutes and email the Oprah Team at: https://www.oprah.com/plugform.jsp?plugId=220 and tell them about my unique ability to inspire, motivate, and inform. If you have changed your body, your waistline, and stood up to take control of your own life because of my information, please email oprah and let her know at https://www.oprah.com/plugform.jsp?plugId=220 Please forward this video to a couple friends that need help. Thanks, and be well, Darin L. Steen http://www.DarinSteen.com (my private facility in Chicago) http://www.FatlossLifestyle.com (my online book) http://www.FatlossMasterMind.com (client success stories)

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