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In continuation of my update "Metformin" GLP-1 receptor agonists, a class of drug used to treat type 2 diabetes, likely trump the widely prescribed metformin for curbing dementia risk in people with the condition, finds the largest study of its kind, published in the open access journal BMJ Open Diabetes Research & Care. The findings suggest that future clinical guidelines for the treatment of type 2 diabetes would do well to consider prioritizing drugs with both blood glucose and neuroprotective effects, say the researchers. Published research suggests that both GLP-1 receptor agonists and metformin, which are widely used to treat type 2 diabetes, protect the brains of people with the disease. But as yet there have been no direct real-world comparisons of the potential impact of these drugs on dementia risk—a risk that is around 70% higher in people with type 2 diabetes. To explore this further, the researchers drew on anonymized electronic health records from a global health research network (Trinetx) spanning the period 2004 to 2024 to track the development of dementia in patients with type 2 diabetes, treated with either GLP-1 receptor agonists or metformin (87,229 patients in each group; average age 58) for at least six consecutive months. There was no significant difference in vascular dementia risk between the two types of drug when used as first line therapy. But GLP-1 receptor agonist use was associated with a significantly lower cumulative (10%) risk of developing dementia, overall, with an incidence of almost 2.5% (2,130 people) compared with an incidence of nearly 5% (4,215 people) for metformin. And specifically, taking this type of drug was associated with a 12% lower risk of developing Alzheimer's disease, and a 25% lower risk of developing non-vascular dementias than metformin use. Further in-depth analyses showed that these positive effects were evident across all age groups, but with the strongest effect among the over 60s, women, and those of white ethnicity. Risk of death from any cause was also lower: nearly 5% of those treated with GLP-1 receptor agonists died compared with nearly 9% of those treated with metformin. "Both medications demonstrate neuroprotective properties, such as reducing neuroinflammation and oxidative stress, improving insulin sensitivity, and enhancing cerebrovascular health, which likely contribute to their benefits in overall dementia," explain the researchers. But unlike metformin, whose benefits primarily derive from systemic metabolic effects, GLP-1 receptor agonists exert direct central nervous system effects by crossing the blood-brain barrier, they add. "However, the multifactorial nature of [vascular dementia], driven by cerebrovascular damage, such as small vessel disease and white matter lesions, poses significant challenges for pharmacological interventions targeting metabolic or neurodegenerative pathways," they continue. This is an observational study, and as such, no firm conclusions can be drawn about cause and effect. And the researchers point out that the tracking period, while sufficient for observing dementia outcomes, may not fully capture long-term cognitive effects, especially given the progressive nature of Alzheimer's disease. REF:https://www.med-chemist.com/2025/07/glp-1-diabetes-drugs-likely-trump.html
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Are you looking to add some sweetness to your keto diet? Look no further than Keto Gummies at Chemist Warehouse! These delicious gummies are the perfect way to satisfy your sweet tooth while staying on track with your low-carb lifestyle. In this buyer’s guide, we will explore everything you need to know about Keto Gummies, from their ingredients to their benefits and where to purchase them. Let’s dive in!
What are Keto Gummies?
Keto Gummies are a convenient and tasty way to incorporate a little sweetness into your ketogenic diet. These gummies are specially formulated to be low in carbs and sugar, making them the perfect treat for those following a keto lifestyle. They are typically made with ingredients like gelatin, water, stevia, and natural flavors to create a delicious snack without any guilt.
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Benefits of Keto Gummies
There are many benefits to incorporating Keto Gummies into your ketogenic diet. One of the most significant advantages is that these gummies can help satisfy your sweet cravings without derailing your progress. By having a pack of Keto Gummies on hand, you can indulge in a guilt-free treat whenever you need a little pick-me-up.
Additionally, Keto Gummies are portable and easy to take on the go, making them a convenient snack option for busy lifestyles. You can stash a pack in your purse, gym bag, or desk drawer for a quick and tasty snack whenever hunger strikes.
Furthermore, Keto Gummies are typically low in calories, making them a great option for those looking to manage their weight while following a ketogenic diet. With fewer carbs and sugar than traditional gummy candies, these gummies can help you stay on track with your health and wellness goals.
Where to Buy Keto Gummies
If you’re ready to try Keto Gummies for yourself, you can find them at your local Chemist Warehouse. Chemist Warehouse is a trusted retailer that offers a wide range of health and wellness products, including Keto Gummies.
When shopping for Keto Gummies at Chemist Warehouse, be sure to check the ingredients list to ensure that they align with your dietary preferences. Look for gummies that are low in carbs and sugar, and free from any artificial additives or preservatives.
Keep in mind that availability may vary depending on your location, so it’s always a good idea to call ahead and check if Keto Gummies are in stock before making the trip. You can also purchase Keto Gummies online from Chemist Warehouse’s website for added convenience.
Tips for Incorporating Keto Gummies into Your Diet
To make the most of your Keto Gummies experience, consider these tips for incorporating them into your ketogenic diet:
1. Enjoy Keto Gummies in moderation: While Keto Gummies are a tasty treat, it’s essential to practice portion control to avoid consuming too many carbs and calories.
2. Pair Keto Gummies with protein or healthy fats: To balance out the sweetness of the gummies, consider pairing them with a source of protein or healthy fats, such as nuts, cheese, or Greek yogurt.
3. Use Keto Gummies as a pre- or post-workout snack: The quick-digesting carbs in Keto Gummies make them an excellent option for fueling your workouts or replenishing glycogen stores after exercise.
Summary & FAQ
In conclusion, Keto Gummies at Chemist Warehouse are a delicious and convenient snack option for those following a ketogenic diet. With their low carb and sugar content, these gummies are the perfect way to satisfy your sweet tooth without derailing your progress. Whether you’re looking for a quick energy boost or a guilt-free treat, Keto Gummies are sure to hit the spot.
If you have any questions about Keto Gummies or how to incorporate them into your diet, check out the FAQ below:
Q: Are Keto Gummies suitable for vegetarians or vegans?
A: Some Keto Gummies may contain gelatin, which is derived from animal sources. Be sure to check the ingredients list for vegetarian or vegan options.
Q: Can I eat Keto Gummies if I have food allergies?
A: Keto Gummies may contain allergens like nuts, dairy, or soy. Always read the label carefully and consult with your healthcare provider if you have any concerns.
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Q: How many Keto Gummies can I eat in a day?
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