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Dr Tamaan K. Osbourne-Roberts reviews the list of patients who probably should not be taking GLP-1 receptor agonists. https://www.medscape.com/viewarticle/glp-1-ras-when-not-prescribe-2024a1000nd8?src=soc_yt -- TRANSCRIPT -- Hi. I'm Tamaan K. Osbourne-Roberts, family medicine physician and lifestyle medicine physician, here to discuss GLP-1 receptor agonist (RA) contraindications — the skinny on when not to prescribe. It can be hard not to think of GLP-1 RAs like Ozempic and Mounjaro as silver bullets, long-awaited miracle drugs that we should probably be putting in the water. And it's true they have the potential to help a lot of people. However, there are definitely groups of patients who should not take these drugs or should take them with caution. They include the following: Patients with a family history of certain cancers. Given that GLP-1 RAs can increase the risk for thyroid cancer, patients with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2 should not take these drugs. Gut motility issues. Since one of the primary mechanisms of action for these drugs is to slow down the gut, patients with gastroparesis — diabetic or otherwise — or other gut motility issues should avoid these drugs. Patients with inflammatory bowel disease also should not use GLP-1 RAs. Pancreatitis. These medications can increase the risk for serious pancreatitis on their own, so use in patients who have had pancreatitis already is not recommended. Renal impairment. An eGFR [estimated glomerular filtrationrate] below threshold, typically around 30 mL/min/1.73 m2, excludes GLP-1 RAs for some patients. Be certain to check the threshold for individual medications before prescribing. And finally, pregnancy. These drugs generally should not be used in pregnancy, and people of childbearing age with the ability to become pregnant should use contraception while taking these medications. GLP-1 RAs are great medications and have the potential to revolutionize obesity medicine, but like all drugs, it's important to use them safely. Knowing when not to prescribe them is an important step in ensuring patient safety and will help ensure they are available for those who need them. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/glp-1-ras-when-not-prescribe-2024a1000nd8?src=soc_yt
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The ketogenic diet has gained immense popularity in recent years, thanks to its promising results in weight loss and overall health improvement. However, sticking to a ketogenic diet can sometimes be challenging, especially when it comes to satisfying your sweet tooth. That’s where Keto Apple Gummy comes in – a delicious and convenient solution for your ketosis-friendly snack needs.
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Keto Apple Gummy is a tasty and guilt-free treat that allows you to indulge in a sweet snack without derailing your ketogenic diet goals. Made with high-quality ingredients and sweetened with natural sugar substitutes like erythritol or stevia, these gummies contain minimal carbohydrates and are perfect for those following a strict keto lifestyle.
Each gummy is packed with flavor and nutrients, making it a satisfying and satisfying snack that won’t spike your blood sugar levels. Whether you’re craving something fruity, chewy, or just a little bit sweet, Keto Apple Gummy has got you covered.
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One of the best things about Keto Apple Gummy is its convenience. These gummies come in individual packages, making them easy to grab and go whenever hunger strikes. Whether you’re at work, on a road trip, or just need a quick pick-me-up between meals, Keto Apple Gummy is the perfect snack to keep you satisfied and energized throughout the day.
Forget about having to spend time preparing complicated keto-friendly desserts – Keto Apple Gummy is here to make your life easier and more delicious. With these gummies on hand, you can indulge in a sweet treat without any of the guilt or hassle that usually comes with traditional desserts.
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Aside from being a tasty and convenient snack option, Keto Apple Gummy offers a variety of health benefits that make it a smart choice for your ketogenic diet. These gummies are rich in fiber, which helps support digestion and keep you feeling full and satisfied for longer periods.
Additionally, Keto Apple Gummy is free from artificial additives and preservatives, making it a wholesome and nutritious snack that you can feel good about eating. Unlike many store-bought gummy candies that are loaded with sugar and unhealthy ingredients, Keto Apple Gummy is a clean and keto-friendly alternative that won’t compromise your health goals.
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1. Are Keto Apple Gummies suitable for those with dietary restrictions?
Yes, Keto Apple Gummies are perfect for individuals following a ketogenic diet, as they contain minimal carbs and are sweetened with natural sugar substitutes. They are also gluten-free, making them suitable for those with gluten intolerances or allergies.
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Currently, Keto Apple Gummy comes in a delicious apple flavor that will remind you of your favorite childhood gummy candies. However, we are always working on introducing new flavors, so stay tuned for more options in the future!
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Are you trying to lose weight?⚖️ Are you considering weight-loss drugs? 💊 Are you intrigued by the growing interest in weight loss drugs and wondering if there's a more natural way to boost your metabolism? Let's talk about GLP-1, the hormone that can help you feel fuller, manage blood sugar, and support weight loss. If you can foster natural GLP- production, there’s a chance you might not need medications like Ozempic. Furthermore, managing your stress can also play a crucial role in managing your weight. Understanding healthy ways to manage your weight can be confusing and overwhelming. That’s why we’re so glad to welcome Dr. Stephanie Dunlop, Founder + Instructor of Club MVMNT, back to our IG Live. Dr. Dunlop offers online coaching and is Founder of the Elite Mom Movement. She joined us back in February to discuss weight gain and hormones. Be sure to check out our Reels feed for part 1 of our chat with Dr. Dunlop. Today, we’re focusing on natural GLP-1 production, and we’re going to talk about how hormones impact weight, ways to manage your weight without pharmaceuticals, the role of stress in weight maintenance, and so much more. Learn more about Dr. Dunlop's services: https://www.clubmvmnt.com/ Get tested for BPA, phthalates, parabens, and other hormone-disrupting chemicals with Million Marker's Detect & Detox Test Kit: https://www.millionmarker.com/
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🔷 DEA and Cannabis: What’s Happening Now? ✅ Proposal to Reschedule Cannabis In 2024, the Department of Health and Human Services (HHS) recommended that the DEA reschedule cannabis from Schedule 1 to Schedule 3 under the Controlled Substances Act (CSA). Schedule 1 includes drugs like heroin and LSD — substances deemed to have no accepted medical use and a high potential for abuse. Schedule 3 includes drugs like ketamine and anabolic steroids — recognized for medical uses and considered to have moderate abuse potential. ⸻ 🏛️ What Rescheduling Would Mean If the DEA finalizes rescheduling cannabis to Schedule III: 🔬 Research Access Improves Researchers would face fewer regulatory barriers. Easier to study medical benefits and risks of cannabis. 💊 Medical Legitimacy Acknowledges that cannabis has accepted medical uses. Could pave the way for FDA-approved cannabis-based therapies. 📈 Business and Tax Changes • Cannabis businesses could potentially: • Deduct expenses under IRS tax code (280E no longer applies to Schedule 3 substances). • Access more financial services, though many federal banking issues would remain. 🚫 Still Not Legal for Adult Use Federally Recreational use would remain federally illegal, even if rescheduled. States’ legalization laws would still conflict with federal law — although enforcement has largely been hands-off in legal states. ⸻ ❗ Key Limits of Rescheduling It would not automatically legalize state-licensed cannabis businesses at the federal level. Still doesn’t allow interstate commerce of cannabis products. Cannabis possession would still be federally criminalized outside medical or research contexts. ⸻ 🔍 Current DEA Process (As of May 2025) DEA is conducting a scientific and regulatory review following HHS’s recommendation. No official final rule yet, but widespread reporting suggests the DEA may agree with reclassification. The final decision will include a public comment period, and may be challenged legally by opponents or supporters. ⸻ 🧭 What Comes Next? If DEA reschedules cannabis: Expect rules for pharmaceutical-style regulation to develop. The move may encourage Congress to pass broader reform (e.g., the STATES Act or federal legalization bills). If DEA rejects the recommendation, political pressure is expected to intensify.
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In recent years, the keto diet has gained immense popularity for its effectiveness in aiding weight loss and improving overall health. Many people have turned to this low-carb, high-fat diet to achieve their fitness goals and improve their well-being. However, sticking to a strict keto diet can be challenging, especially for those with a sweet tooth. This is where Weight Loss Keto Gummies come in – a convenient and delicious way to stay on track with your ketogenic lifestyle while satisfying your cravings for something sweet.
What are Weight Loss Keto Gummies?
Weight Loss Keto Gummies are a supplement that combines the benefits of a traditional keto diet with the convenience of a tasty gummy. These gummies are specially formulated to help support ketosis, a metabolic state where your body burns fat for energy instead of carbohydrates. By providing your body with exogenous ketones, Weight Loss Keto Gummies can help you reach ketosis faster and stay there longer, making it easier to burn fat and lose weight.
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Additionally, Weight Loss Keto Gummies are packed with other ingredients that can further enhance your weight loss efforts. These may include metabolism-boosting compounds like green tea extract and Garcinia Cambogia, as well as appetite-suppressing ingredients like apple cider vinegar and fiber. By incorporating these gummies into your daily routine, you can potentially amplify the effects of your keto diet and achieve your weight loss goals more efficiently.
How do Weight Loss Keto Gummies work?
When you consume Weight Loss Keto Gummies, the exogenous ketones they contain can help jumpstart ketosis in your body. This means that instead of relying on glucose from carbohydrates for fuel, your body will start using fat stores for energy, leading to weight loss. By consistently taking these gummies, you can maintain ketosis and continue burning fat, even if you occasionally indulge in higher-carb foods.
In addition to supporting ketosis, Weight Loss Keto Gummies may also help curb your cravings for sugary treats and snacks. The sweet taste of the gummies can satisfy your dessert cravings without derailing your progress on the keto diet. This can be especially beneficial for those who struggle with staying disciplined when it comes to avoiding high-carb foods. With Weight Loss Keto Gummies, you can enjoy a guilt-free treat while staying on track with your weight loss journey.
Are Weight Loss Keto Gummies compatible with ketogenic diets?
Yes, Weight Loss Keto Gummies are specifically designed to be compatible with ketogenic diets. These gummies are formulated with high-quality ingredients that align with the principles of the keto diet, such as being low in carbs and high in healthy fats. Additionally, the exogenous ketones in the gummies can help support ketosis, the hallmark of a successful ketogenic diet.
When choosing Weight Loss Keto Gummies, it’s essential to check the nutritional information and ingredients list to ensure they fit within your daily macros and dietary preferences. Some gummies may contain added sugars or artificial ingredients that could potentially kick you out of ketosis. Opt for gummies that are made with natural sweeteners like stevia or erythritol and are free from any hidden carbs or fillers.
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In conclusion, Weight Loss Keto Gummies can be a valuable addition to your ketogenic lifestyle, providing a convenient and enjoyable way to support your weight loss journey. By incorporating these gummies into your daily routine, you can potentially accelerate your progress in reaching ketosis, burning fat, and achieving your fitness goals. Remember to pair Weight Loss Keto Gummies with a balanced diet and regular exercise for optimal results. Overall, these gummies offer a tasty and effective solution for individuals looking to enhance their keto diet experience.