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Downsized News: Breakthroughs and Industry Shifts in GLP-1 Treatments In this episode of the Downsized News, Laraine and Christopher Durham deliver the latest updates on GLP-1 medications on Monday, June 2nd, 2025. Key topics include significant data releases by Eli Lilly at the upcoming American Diabetes Association's Scientific Sessions concerning Tirzepatide's effects on kidney function and weight loss compared to Semaglutide. The episode also explores new forms of GLP-1 treatments, such as the Orfroglipron pill and the Retatrutide triple-action hormone, as well as an updated weekly insulin option by Lilly. Additionally, a comprehensive breakdown of a study on high-dose Semaglutide treatments for diabetes and obesity discusses the balance between increased weight loss and rising side effects. The discussion shifts to industry challenges, like Hims Inc.'s layoffs due to FDA crackdowns on compounded GLP-1s, and a new ISSA course designed to help athletic trainers support GLP-1 users. Also covered is the intense industry debate over compounded medications, a major court ruling in India impacting Semaglutide sales, and competitive developments in China's obesity treatment market. The episode concludes with highlights of an innovative partnership between Nxtera Pharma and Eli Lilly aiming at new metabolic treatments. The hosts encourage viewers to stay informed and share personal insights on navigating GLP-1 treatments. DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store Join CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join DOWNSIZED WEBSITE: https://thedownsized.org/ FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ 00:00 Introduction and Overview 01:04 Eli Lilly's Latest Data and Innovations 05:21 High Dose Semaglutide Study Insights 10:14 Hims Layoffs and FDA Crackdown 11:51 New Training Course for GLP-1 Trainers 13:58 Compounded Medications Debate 17:08 Legal Battles and Market Dynamics in India 20:16 NextEra Pharma and Eli Lilly Partnership 21:52 Upcoming Competition in China's GLP-1 Market 24:25 Conclusion and Final Thoughts

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Calories 560 Protein 27g 1. 130 g Boiled green peas 2. Hundred grams Paneer 3. 10 g Walnut 4. 4 tomato purée 5. 15 ML coconut oil 6. Two green chilli chopped 7. 1/4 Teaspoon turmeric powder 8. 1/4 Teaspoon Garam masala 9. 1/4 Teaspoon Jeera powder 10. 1/2 Teaspoon coriander powder 11. Salt 12. 1 teaspoon jeera 13. 1/2 Teaspoon Hing 14. Coriander leaf Preparation of this recipe 1. Take a mixer jar 2. Add four tomatoes 3. Mix it into fine juice 4. Now, tomato purée is ready. Keep it aside. 5. Again, take a mixer jar 6. Add Paneer and walnut along with some water 7. Mix it into a Fine paste 8. And keep it aside 9. Now take a pan 10. Add oil, Jeera and Hing 11. Mix it for 10 seconds in medium flame 12. Now add tomato Purée 13. Mix it well until it get boil 14. Now add all the masala and salt 15. Mix it for seven to eight minutes in medium 16. It will come to a thick gravy 17. Now add Paneer paste 18. Mix it for two minutes in high flame 19. Now add boiled green peas, Coriander Leaf, Green chilli 20. Mix it all in medium flame for 2 to 3 minutes 21. Check the salt and switch off the flame 22. Share it and enjoy it!!!

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