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incretin effect| incretin effect glp-1| incretin effect explained| incretin effect in diabetes| incretin hormones| incretin based therapy of diabetes ▪ Incretins are a group of metabolic hormones that stimulate a decrease in blood glucose levels. Gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are the two primary incretin hormones secreted from the intestine on ingestion of glucose or nutrients to stimulate insulin secretion from pancreatic β cells. The major mechanism of metabolism of the incretins is cleavage by dipeptidyl peptidase 4 (DPP4), an enzyme that is ubiquitously expressed, including in endothelial cells. ▪ Two pharmacological approaches have been taken to enhance the incretin effect in type 2 diabetes. One approach is to administer GLP-1 'analogues' (GLP-1 receptor agonists) that are resistant to cleavage by DPP4. The other approach is to inhibit DPP4 activity. This effectively increases the half-life and therefore the circulating concentrations of the incretins. ▪ In summary, Ingested glucose causes secretion of incretins from GI tract. These ingredients then increase insulin secretion from the pancreas. Anti-diabetic drugs targeting this mechanism are glp1 analogues and dpp4 inhibitors. And in this way, by increasing insulin secretion, the incretins lower blood glucose. Chapters: 0:00 - Insulin Secretion Mechanism 0:42 - Incretin Effect 1:10 - Incretin Hormones 1:26 - Glucagon-like peptide-1 (GLP-1) Hormone 2:19 - Problem in Diabetes 2:35 - GLP-1 analogues and DPP-4 inhibitors 3:24 - Summary of Incretin Effect incretin hormones, incretin effect, incretin effect glp-1, incretin effect explained, incretin effect in diabetes, insulin, diabetes, glucagon like peptide 1, incretin based therapy of diabetes, incretin pathway, incretin and glp-1, glp 1 analogs, dpp4 inhibitors, sitagliptin, vildagliptin, exenatide, liraglutide, oral antidiabetic drugs, mechanism of insulin secretion, insulin secretion, insulin physiology, insulin pharmacology, diabetes mellitus, medicine, pharmacyd by asim ☕ Buy Me A Coffee: https://www.buymeacoffee.com/pharmacyd 💡 Facebook: https://web.facebook.com/pharmacyd0929 For any Queries and Suggestions Email on: [email protected] Disclaimer: "Content is For Informational & Education Purpose Only, Creamed From Various Authentic Books of Pharmacy & Medicine. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition." A Famous Quote is: "What We Know is a Drop. What We Don't Know is an Ocean".

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keywords Keto, Carnivore Diet, Addiction, Emotional Eating, Support Systems, Dopamine, GLP-1 Agonists, Self-Soothing, Family Dynamics, Recovery summary In this episode, Dr. Cammy and Mike Collins discuss the challenges of transitioning from a standard American diet to a keto and carnivore lifestyle, focusing on addiction, emotional triggers, and the importance of support systems. Dr. Cammy shares her struggles with sugar addiction and the decision to use GLP-1 agonists, while Mike emphasizes the need for emotional work and connection in recovery. They explore the impact of family dynamics on eating habits and the role of dopamine in addiction, ultimately committing to ongoing support and personal growth. takeaways Dr. Cammy is transitioning from a standard American diet to a keto and carnivore lifestyle. She struggles with sugar addiction and the decision to use GLP-1 agonists. The importance of emotional work in overcoming addiction is emphasized. Family dynamics play a significant role in eating habits and self-soothing behaviors. Building connections and support systems is crucial for recovery. Dopamine levels are affected by addiction and can influence cravings. Perfectionism creates stress and anxiety in the recovery process. Progress is more important than perfection in the journey of recovery. Reaching out for support is a vital step in overcoming addiction. The conversation highlights the ongoing nature of addiction recovery and the need for continuous self-reflection. Sound Bites "The opposite of addiction is connection." "I have to believe that that will happen." "Progress, not perfection, right?" Chapters 00:00 Introduction to Keto and Carnivore Lifestyle 02:32 The Decision to Use GLP-1 Agonist 05:34 Understanding Addiction and Cravings 08:14 The Role of Caffeine in Addiction 10:43 Emotional Connections and Support Systems 13:26 Exploring Childhood Influences on Behavior 16:08 The Struggle with Perfectionism and Anxiety 18:36 Building Connections and Overcoming Isolation 24:46 The Power of Vulnerability and Connection 26:49 Understanding Addiction and Decision Making 28:42 Dopamine and Emotional Healing 31:50 The Role of Support in Recovery 35:06 Commitment to Change and Self-Reflection 37:14 Navigating New Territory with GLP-1s

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Post Malone, the American rapper and singer-songwriter, has been making headlines lately for his impressive weight loss transformation. Fans have been curious to know what changes he made in his fitness routine to achieve this remarkable feat. In this article, we will delve into the details of Post Malone’s weight loss journey and explore what modifications he made in his lifestyle to shed those extra pounds.Keto Blast Us Diet Shark Tank Pills Where To Buy

The Beginning of Post Malone’s Weight Loss Journey

Post Malone first caught the public’s attention with his hit songs like “White Iverson” and “Rockstar.” However, in recent years, he has also been grabbing headlines for his noticeable weight loss. The journey to a healthier lifestyle for Post Malone began with a decision to prioritize his physical well-being. Like many individuals, he faced challenges in maintaining a balanced diet and exercise regimen while juggling a hectic schedule as a musician.





Despite the demands of his profession, Post Malone recognized the importance of taking care of his body and decided to make significant changes to his fitness routine. He sought guidance from fitness experts and nutritionists to help him embark on his weight loss journey. With determination and dedication, Post Malone started incorporating healthier habits into his daily life, which eventually led to visible results.

Changes in Post Malone’s Fitness Routine

One of the key changes that Post Malone made in his fitness routine was adopting a more structured workout plan. He began incorporating a mix of cardio, strength training, and flexibility exercises into his daily routine. By diversifying his workouts, Post Malone was able to target different muscle groups and keep his body challenged, leading to better overall fitness and weight loss.

In addition to his workout plan, Post Malone also made adjustments to his diet. He worked closely with nutritionists to create a balanced meal plan that included a variety of healthy foods such as lean proteins, fruits, vegetables, and whole grains. By focusing on nourishing his body with nutrient-dense foods, Post Malone was able to fuel his workouts effectively and support his weight loss goals.

Maintaining Consistency and Discipline

Consistency and discipline played a crucial role in Post Malone’s weight loss journey. Despite his busy schedule and the temptations of the music industry, he remained committed to his fitness goals. Post Malone made a conscious effort to prioritize his health and well-being, even when faced with challenges or setbacks along the way.

By staying consistent with his workout routine and dietary habits, Post Malone was able to see steady progress in his weight loss efforts. He understood that sustainable changes take time and that results do not happen overnight. Through perseverance and determination, Post Malone successfully transformed his physique and inspired many of his fans to prioritize their own health and fitness.

Impact of Post Malone’s Weight Loss

Post Malone’s weight loss journey has not only improved his physical appearance but has also had a positive impact on his overall well-being. By prioritizing his health and making sustainable lifestyle changes, he has enhanced his energy levels, confidence, and mental clarity. Post Malone’s transformation serves as a testament to the power of dedication and perseverance in achieving fitness goals.

As Post Malone continues to maintain his healthier lifestyle, he serves as a source of inspiration for many individuals who are looking to make positive changes in their own lives. His weight loss journey highlights the importance of self-care and the benefits of prioritizing health and well-being. Post Malone’s commitment to his fitness goals serves as a reminder that with determination and perseverance, anything is possible.

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