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Doug Long, BA, MBA, vice president of Industry Relations at IQVIA, shares what's happening in the growing GLP-1 and biosimilars space. Long was a presenter at the annual AMCP 2025 meeting in Houston, where he discussed these topics and more earlier this week.
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이전에 사용되던 주사형 비만치료제와 차별화된 새로운 경구 비만치료제, Orforglipron에 대한 소식을 전하려 합니다. Orforglipron은 기존의 Wegovy, Mounjaro, Saxenda 등과 같은 GLP-1 agonist 기반의 약이지만, 가장 큰 차이점은 이 약이 복용형이라는 점입니다. 주사를 매일 또는 일주일에 한 번씩 맞는 것을 꺼려하는 환자분들에게 이 약은 매우 큰 도움이 될 것입니다. 약의 효과에 대해 말씀드리자면, 36주간 관찰한 결과 최대 용량을 복용했을 때 체중감소율이 14.7%에 달하였고, 이는 약 80kg인 사람이라면 약 11-12kg의 체중감소를 의미합니다. 또한, 흥미로운 점은 이 체중 감소 추세가 36주에서도 계속 이어지고 있으며, 이는 주사형 약물과 비교해도 결코 뒤지지 않는 효과입니다. 부작용에 관해서는 GLP-1 agonist 약들과 유사한 수준이었으며, 대부분의 참여자들이 약 복용에 문제가 없었다는 결과를 보여주었습니다. 마지막으로, 이 약이 곧 FDA의 승인을 받을 것으로 기대되며, 그렇게 되면 새로운 사실들을 영상을 통해 계속 공유하도록 하겠습니다.
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Transformation Journey of Joe Thomas
Joe Thomas, the former NFL offensive tackle and a Hall of Famer, is well-known not just for his stellar performances on the football field but also for his recent transformation in 2024, where he shed an impressive 50 pounds. This weight loss journey has captivated fans and fitness enthusiasts alike, demonstrating that even the most accomplished athletes can face personal challenges and make significant changes in their lives. As fans, we often look at the physical prowess of players like Thomas during their careers, but what is often overlooked is their daily lives post-retirement and the struggles they face with health and fitness.
In recent years, Thomas has transitioned from the demanding world of professional football to a life that embraces a healthier lifestyle. After years of competing at the highest level, maintaining optimum physical fitness post-retirement can be unexpectedly challenging. Thomas’s story is one of courage, determination, and a desire for better health. It highlights the importance of setting tangible goals, implementing a disciplined regimen, and overcoming personal hurdles. His journey is not simply about weight loss but signifies a commitment to living a life full of vitality, energy, and, most importantly, health.
In this article, we will explore various aspects of Joe Thomas’s weight loss journey. We’ll discuss the motivations behind his decision to lose weight, the methods he utilized to achieve his fitness goals, the challenges he faced along the way, and the impact his transformation has on his life and career. This detailed exploration will not only showcase Thomas’s journey but also provide insights into how anyone can embark on a similar path, regardless of their background or previous athletic experience. Join us as we delve into the remarkable story of Joe Thomas and learn how he dropped 50 pounds in 2024.
Motivation Behind the Change
Every transformative journey begins with a motivation or a triggering event that propels one into action. For Joe Thomas, this catalyst was multifaceted. After retiring from the NFL, he started to reflect on his lifestyle choices and the impact they had on his overall health. The physical demands of playing professional football had taken a toll on his body, leading to several injuries and a sedentary lifestyle post-career. He recognized that he needed to put his health at the forefront to enjoy life fully and remain active with his family and community.
Another critical motivation was Thomas’s desire to set a positive example for his children and the younger generation. As a public figure, he understood that his choices would be observed by many. By prioritizing his health and wellness, he aimed to inspire others, especially young athletes, to take their physical health seriously. This responsibility weighed heavily on him, and he wanted to demonstrate that maintaining one’s health is achievable and essential, even after stepping away from the spotlight of professional sports.
Moreover, Thomas faced health-related issues typical for many former professional athletes, such as weight gain, limited mobility, and potential long-term health risks associated with obesity. After carefully examining these factors, Joe realized that making changes was not just about aesthetics but about preventing serious health issues in the future. This holistic understanding of fitness became a pivotal driver of his transformation, prompting him to take actionable steps toward a healthier lifestyle.
The Strategy of Weight Loss
With motivation firmly established, Joe Thomas engaged in developing a comprehensive strategy for his weight loss journey. Central to this strategy was a significant change in his diet. Understanding that what he consumed would affect his energy levels and overall health, Thomas committed to adopting a balanced diet rich in nutrients. He eliminated processed foods, sugars, and unhealthy fats and replaced them with whole foods, fruits, vegetables, lean proteins, and healthy fats. This change not only helped him shed pounds but also improved his energy and well-being.
In addition to dietary modifications, Thomas introduced a rigorous exercise regimen tailored to his current fitness level. He incorporated a mix of cardiovascular exercises, strength training, and flexibility workouts into his weekly routine. Knowing that muscle mass plays a crucial role in metabolism, he focused on building lean muscle while simultaneously burning fat. Thomas frequently partnered with fitness experts who guided him through exercises that were gentle on his joints, which was a concern given his history of injuries.
Moreover, accountability played a crucial role in Thomas’s weight loss strategy. He joined support groups and connected with others on similar journeys. Acknowledging the challenges associated with significant lifestyle changes, he sought motivation from various sources, including friends, family, and online communities. Social media became a platform for him to share his progress, inspire, and motivate others, creating a sense of community and shared goals in his weight loss journey.
Overcoming Challenges
Transforming one’s lifestyle is often fraught with challenges, and Joe Thomas faced his share throughout his weight loss journey. The first significant hurdle was the mental engagement required to switch from being a competitive athlete to embracing a healthier lifestyle. For years, Thomas had relied on a strict regimen and high caloric intake to fuel his athletic performance. Adjusting his mindset to a balanced approach to food and exercise was paramount, and it took time and determination to shift this mental paradigm.
Physical challenges were also prevalent, particularly as Thomas began to ramp up his exercise routine. The rigorous training that defined his athletic career had to be modified to suit his current body condition and capabilities. Adapting to a new training routine required patience, especially as he faced days when he felt demotivated or encountered physical limitations post-retirement. Overcoming these physical challenges often meant drawing upon the discipline he developed throughout his football career, reminding him that building a new foundation of fitness was a gradual process.
Moreover, the temptation to revert to old habits loomed large during his journey. After years of living a certain lifestyle, familiar comforts and indulgences often called out to him. Navigating social situations where unhealthy food choices were prevalent presented its own set of difficulties. Joe countered these challenges by actively planning meals, surrounding himself with a supportive network, and engaging in regular self-reflection to understand and address these potential pitfalls. Each challenge faced was a stepping stone toward reinforcing his commitment to his newfound lifestyle.
Impact and Insights
Joe Thomas’s weight loss journey has had a profound impact not only on his physical appearance but also on his overall quality of life. Shedding 50 pounds has empowered him and enhanced his mobility and energy levels, allowing him to participate more actively in daily activities. He has experienced renewed joy in playing with his children, engaging in outdoor sports, and participating in community events that he previously found difficult due to his weight. This new lifestyle has revitalized his passion for fitness and health, renewing his appreciation for the simple joys of life.
Furthermore, Thomas’s transformation has had a ripple effect in the lives of others. As he openly shares his journey through social media and public speaking engagements, many people are motivated and inspired by his story. The visibility of his commitment to health resonates with fans and athletes, showcasing that positive changes can occur regardless of past experiences. His story serves as a representation of hope, illustrating that weight loss is not merely an aesthetic endeavor but a significant investment toward overall health and well-being.
In essence, Joe Thomas has not only transformed his physique but has also become an advocate for health and wellness. His insights illuminate the importance of loving oneself, embracing the journey, and recognizing that setbacks are part of the process. By sharing his experiences, Thomas encourages others to embark on their paths with determination and resilience, instilling the belief that lasting change is possible for everyone, irrespective of their background or starting point.
Reflections on the Journey
As we reflect on Joe Thomas’s journey of weight loss and personal growth, it becomes evident that profound changes require more than just physical effort; they demand a strong mindset and an unwavering commitment to a healthier future. Thomas’s story serves as a testament to the resilience of the human spirit, showcasing that it is never too late to make significant life changes. His journey reflects a movement towards self-improvement, illustrating the power of setting goals and achieving them through consistent effort and determination.
For those inspired by Thomas’s journey, it emphasizes the importance of acknowledging one’s motivations and laying down a clear path toward achieving them. Whether for health, aesthetics, or longevity, understanding why you want to lose weight or change your lifestyle can provide a strong foundation for lasting transformation. Joe’s journey encourages individuals to engage in self-reflection, enabling them to embark on their unique journeys with clarity and purpose.
Ultimately, the key takeaway from Joe Thomas’s experience is that weight loss is not merely a number on the scale or a change in appearance. It is a holistic endeavor that encompasses mental and emotional health. Maintaining a healthy lifestyle is about cultivating habits of discipline and self-care that can enrich overall quality of life. As such, Joe’s transformation invites everyone to embrace their journeys and strive for a better, healthier version of themselves, regardless of the obstacles that may lie ahead.
FAQs about Joe Thomas’s Weight Loss
Many individuals seeking to lose weight often have questions, and Joe Thomas’s journey prompts several inquiries from fans and those on similar paths. A common question is what inspired Joe to initiate such significant changes in his life post-NFL. In interviews, Thomas has shared that his children were a significant motivation, prompting him to seek a healthier lifestyle to be more active and engaged in their lives, setting a positive example for them.
Another frequently asked question concerns the methods Thomas utilized for his weight loss. Thomas has highlighted the importance of a balanced diet and regular exercise as integral components of his transformation. He shifted towards whole food options, eliminated sugary and processed items, and engaged in a mixed exercise routine that included cardio and strength training. His approach demonstrates that a comprehensive plan, combining nutrition and physical activity, is critical for individuals pursuing weight loss and improved health.
Lastly, many are curious about the challenges Thomas faced throughout his weight loss journey. Joe openly discusses the mental hurdles associated with shifting from a competitive athlete’s mindset to a more balanced approach to health. The temptation to revert to old habits and the physical challenges posed by his transition are also aspects he faced. However, through discipline, support, and self-reflection, Thomas overcame these challenges, proving that persistence is vital in any transformative journey.
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Oprah Winfrey, the iconic media mogul and philanthropist, has been a role model for millions of people around the world. Known for her inspiring journey to wellness and weight loss, Oprah has recently introduced a new approach to achieving a healthier lifestyle – the Oprah Winfrey Keto Gummy. This innovative product has gained popularity not only because of Oprah’s endorsement but also due to its effectiveness in promoting weight loss and overall well-being.
The Power of Keto Gummies
Keto gummies have been gaining traction in the health and wellness industry for their ability to support weight loss and enhance energy levels. These gummies are specially formulated to provide the body with the essential nutrients and ketones needed to enter a state of ketosis, where the body burns fat for fuel instead of carbohydrates. By incorporating keto gummies into their daily routine, individuals can experience a boost in metabolism, increased energy levels, and improved mental clarity.
One of the key advantages of keto gummies is their convenience and ease of use. Unlike traditional supplements or diets that require meticulous planning and preparation, keto gummies can be effortlessly incorporated into any lifestyle. Whether you’re on the go or at home, simply pop a gummy in your mouth to kickstart your journey to a healthier you.
Moreover, keto gummies are a delicious and enjoyable way to support weight loss goals. With a variety of flavors to choose from, including fruity options like raspberry and blueberry, these gummies make sticking to a ketogenic diet more enjoyable. Say goodbye to bland and boring meals – with keto gummies, you can satisfy your sweet tooth while staying on track with your weight loss journey.
Oprah Winfrey’s Endorsement
As a well-known advocate for health and wellness, Oprah Winfrey has always been transparent about her struggles with weight loss and her journey to self-improvement. Her endorsement of the Oprah Winfrey Keto Gummy is a testament to the product’s efficacy and positive impact on her own life. Oprah’s loyal fan base looks to her for inspiration and guidance, making her endorsement of the keto gummies a significant milestone in the health and wellness industry.
By partnering with a reputable brand that prioritizes quality and effectiveness, Oprah Winfrey has stamped her approval on a product that aligns with her values and commitment to promoting a healthy lifestyle. With Oprah’s seal of approval, the Oprah Winfrey Keto Gummy has garnered widespread attention and accolades from consumers who trust her judgment and expertise in the wellness space.
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For Oprah Winfrey, the journey to optimal health has been a lifelong pursuit filled with challenges and triumphs. By sharing her experiences and endorsing products like the Oprah Winfrey Keto Gummy, Oprah continues to inspire millions of people to prioritize their well-being and make positive changes in their lives. Her support of the keto gummies serves as a beacon of hope for those on their own wellness journey, proving that it’s never too late to take control of your health.
FAQ
Q: How do keto gummies promote weight loss?
A: Keto gummies contain a blend of nutrients and ketones that help the body enter a state of ketosis, where it burns fat for fuel. This metabolic process supports weight loss and enhances energy levels.
Q: Are keto gummies safe to use?
A: Keto gummies made with high-quality ingredients are generally safe for consumption. It is essential to read the product label and consult with a healthcare professional before incorporating them into your regimen.

Q: Can anyone use keto gummies?
A: While keto gummies are suitable for most individuals, those with specific health conditions or dietary restrictions should consult with a healthcare provider before using them. Pregnant or nursing women should also exercise caution when considering keto gummies.
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Brian Sekula, PHD in physiology and President of the Performance Health Institute shares about his proven program that can provide a way for users of Ozempic, Wegovy and other GLP-1 inhibitor drugs to continue to get the benefits of the drug, including weight loss, when no longer taking the drugs. In this way, they can get the benefits without the side effects, including a continuous sick and nauseous feeling and muscle loss. Brian's program, originally developed to help diabetics get off insulin permanently. His program is focused around 4 main areas - diet, excercise, stress management, and group support. Brian has seen his clients achieve much success in achieving the goal of getting off insulin and most importantly having a much more fullfilling, active, and energetic lives.
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