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The GLP-1 Journey: Insights and Experiences from the Your Weight Matters Conference In this engaging episode, hosts Christopher and Laraine Durham bring you a special Downsized Dish interview recorded live from the Your Weight Matters conference in Arlington, Virginia. The event, organized by the Obesity Action Coalition, brings together individuals who are navigating their weight loss journeys using GLP-1 medications such as Zepbound, Mounjaro, and compounded Tirzepatide. Their guest, Mike on a Mission, shares his heartfelt story of losing 112 pounds and how these medications have changed his life. He discusses the impact of being diagnosed with type 2 diabetes, his struggles before finding these medications, and the emotional relief of realizing that obesity is a disease rather than a personal failing. Mike, a legal education strategist, delves into his experiences with social media advocacy, the importance of access to medication, and the benefits of building a supportive care team. He also talks about how his taste preferences have changed, highlighting the significant role of dietary changes and the importance of getting enough protein. Listeners will hear about the robust advocacy efforts on Capitol Hill to expand access to obesity treatments via legislative measures such as the Treat and Reduce Obesity Act. Mike emphasizes the importance of fighting for health, building a robust support system, and using social media as a tool for education and community building. They also touch upon the importance of sustainable weight loss, managing expectations, and the emotional aspects of living with and managing obesity. The episode concludes with an invitation for others to share their stories on Downsized Dish and a teaser for the upcoming Downsized cruise, promising even more community engagement and support. If you're navigating your weight loss journey and need firsthand advice and inspiration, this episode is a must-listen. ME AGAIN APP: https://apps.apple.com/us/app/meagain-glp-1-all-in-one-app/id6744178534 DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store As an Amazon Associate I earn from qualifying purchases. DOWNSIZED WEBSITE: https://thedownsized.org/ BOOK THE DOWNSIZED AT SEA CRUISE 2026: https://thedownsized.org/downsized-at-sea-2026/ JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ 00:00 Introduction and Welcome 00:22 Meet Mike: A Journey of Transformation 00:30 The Impact of GLP-1s on Daily Life 01:06 Social Media and Community Support 01:23 Personal Weight Loss Stories 01:44 Mike's Background and Struggles 02:24 The Turning Point: Discovering GLP-1s 04:36 The Emotional Journey of Weight Loss 08:30 Managing Side Effects and Dosage 17:42 Exercise and Lifestyle Changes 20:32 Diet and Taste Changes 22:06 Discussing the Best Protein Options 22:35 Morning Routine and High Protein Breakfast 23:25 The Importance of Monitoring Carbs and Glucose 23:53 Journey to TikTok and Its Impact 27:35 Advocacy and the Obesity Action Coalition 30:23 Challenges with Insurance and Medication Access 35:16 Doctors on TikTok and Their Insights 39:42 Final Thoughts and Future Plans 43:28 Conclusion and How to Connect

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Why am I not losing weight on semaglutide? Are you wondering why semaglutide, the weight loss miracle for many, isn't delivering the results you expected? Is your struggle with weight loss despite using this medication leaving you frustrated? If so, you're not alone, and the reasons behind this are more complex than you might think. I'm Dr. Will Haas from VYVE Wellness, and in this video, we'll dive deep into why semaglutide may not be working for you and what you can do about it. Semaglutide has gained popularity for its appetite-suppressing and fat-reducing properties, but not everyone sees the same success. If you're not losing weight on semaglutide, several underlying factors could be at play. First and foremost, inflammation is a significant factor that often flies under the radar. Chronic inflammation messes with your metabolism, leading to insulin resistance, which hinders weight loss by making it harder for your body to regulate blood sugar and control cravings. This can cause leptin resistance, too, making it difficult for your brain to recognize when you're full. So, even though you're taking semaglutide, inflammation could be one reason you're not seeing the scale move. Another crucial factor is nutrient deficiencies. If your body lacks essential nutrients like vitamin D, iron, or magnesium, it won't function at its best, and this includes metabolism. These deficiencies can cause fatigue, slower metabolism, and even more fat storage, especially when magnesium levels are low, disrupting glucose and insulin balance. If you're feeling sluggish and not losing weight, it's essential to assess whether you're getting enough of these critical nutrients to support your weight loss journey with semaglutide. Gut health is another key element in weight management that many people overlook. An unhealthy gut microbiome can make it harder to lose weight because it interferes with digestion, nutrient absorption, and even hormone regulation. When your gut bacteria are out of balance, your body might extract more calories from the food you eat, store more fat, and mess with your hunger and fullness signals. Maintaining a healthy gut is critical to making semaglutide work effectively, so don't underestimate the importance of gut health in your weight loss efforts. Hormonal imbalances, particularly involving thyroid, insulin, and cortisol, can also sabotage your progress. Thyroid hormones regulate metabolism, and if they're out of whack, it can slow down your ability to lose weight, no matter how hard you try. Cortisol, the stress hormone, is another big player. Elevated cortisol levels can increase your appetite, especially for unhealthy foods, and cause more fat storage, particularly in the belly area. These hormonal imbalances can make semaglutide less effective, so addressing them is critical. Lastly, mitochondrial health is often an overlooked piece of the puzzle. Mitochondria are the powerhouses of your cells, responsible for turning food into energy. When they're not functioning properly, your metabolism slows down, leading to fewer calories burned and more fat stored. Poor mitochondrial health can also increase oxidative stress and inflammation, further complicating weight loss efforts. If your energy levels are low and you're struggling to exercise, poor mitochondrial function could be the reason semaglutide isn't working as expected. In this video, I'll guide you through each of these factors-how inflammation, nutrient deficiencies, gut health, hormonal imbalances, and mitochondrial function can affect your weight loss on semaglutide. I'll also provide actionable tips on how to address these issues and optimize your weight loss journey. Don't get discouraged; understanding these challenges is the first step toward overcoming them. If you've found this video helpful, make sure to connect with me, subscribe to the channel, leave your comments below, and like the video. Stay tuned for more insights into weight loss and wellness from VYVE Wellness. Together, we can achieve lasting results. Watch full video here: https://pxl.to/VYVE/xnd00pc ***************************************************************** Join us on an incredible journey and never miss an update. Subscribe now to be a part of our growing community 🔔: https://pxl.to/VYVE/7exu9h Dive deeper into our world and connect with us through our social platforms. We can't wait to share more with you! 🌟 Instagram: https://pxl.to/VYVE/tdwizta Facebook: https://pxl.to/VYVE/u5kjkl Website: https://pxl.to/VYVE/fmfklvk #SemaglutideWeightLoss #WhySemaglutideIsntWorking #InsulinResistance #GutHealthAndWeightLoss #SemaglutideNotWorking #semaglutide #weightlossrecipe

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We talk a lot about attraction on this channel. And many of you say you feel "unattractive". A lot of this can be fixed if we take a look at our diet. So today, we will be talking about how diet affects your appearance. Ever wondered how your diet impacts your skin, hair, and overall appearance? In this video, we dive into the fascinating connection between what you eat and how you look. From glowing skin to shiny hair, discover the foods that can enhance your natural beauty and those that might be holding you back. Join us as we explore the science behind diet and appearance, and learn how to make simple dietary changes that can lead to stunning results. Disclaimer: We are not professional doctors or nutritionists. The information provided in this video is for informational purposes only and should not be considered as medical advice. Always consult with a healthcare professional or a registered dietitian before making any significant changes to your diet or health routine. Your well-being is important, and professional guidance is essential for personalized advice. Credits: Writer: Syazwana Amirah Editor: Caitlin McColl Script Manager: Kelly Soong Voice Over: Amanda Silvera (http://www.youtube.com/amandasilvera ) Animation: Avery (new animator) Youtube Manager: Cindy Cheong DISCLAIMER: This video may contain information that can be triggering to those suffering from eating disorders or who have an unhealthy relationship with food or body image. If you are struggling, we highly advise you to seek help from a qualified mental health professional. REFERENCES Aragno, M., & Mastrocola, R. (2017). Dietary Sugars and Endogenous Formation of Advanced Glycation Endproducts: Emerging Mechanisms of Disease. Nutrients, 9(4), 385. https://doi.org/10.3390/nu9040385 Havlíček, J., & Lenochova, P. (2006). The Effect of Meat Consumption on Body Odor Attractiveness. Chemical Senses, 31(8), 747–752. doi.org/10.1093/chemse/bjl017 Monjazeb, S. (2021, December 8). The Effects of Alcohol on Skin. U.S. Dermatology Partners. Retrieved March 1, 2023, from www.usdermatologypartners.com/blog/effects-of-alcohol-on-skin/ Prentice, A. M., & Jebb, S. A. (2003). Fast foods, energy density and obesity: a possible mechanistic link. Obesity Reviews, 4(4), 187–194. doi.org/10.1046/j.1467-789x.2003.00117.x Van Drielen, K., Gunn, D., Noordam, R., Griffiths, C. E., Westendorp, R. G. J., De Craen, A. J. M., & Van Heemst, D. (2015). Disentangling the effects of circulating IGF-1, glucose, and cortisol on features of perceived age. Age, 37(3). doi.org/10.1007/s11357-015-9771-3 Vrcek, I., Ozgur, O., & Nakra, T. (2016). Infraorbital dark circles: A review of the pathogenesis, evaluation and treatment. Journal of Cutaneous and Aesthetic Surgery, 9(2), 65. doi.org/10.4103/0974-2077.184046 Xie, J., Wang, D., Ling, S., Yang, G., Yang, Y., & Chen, W. (2019). High-Salt Diet Causes Sleep Fragmentation in Young Drosophila Through Circadian Rhythm and Dopaminergic Systems. Frontiers in Neuroscience, 13. doi.org/10.3389/fnins.2019.01271