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GLP1 agonists (GLP1a), including semaglutide and tirzepatide, were initially developed for diabetes mellitus (DM) management but are increasingly used for obesity. Female factor infertility has been found to improve after exposure to GLP1a, though it is unclear if the effect is related to obesity or other drug effects. The impact of GLP1a on male factor infertility has not been fully described. This study sought to assess improvements in semen analysis (SA) parameters in men with abnormal SA, while controlling for DM and body mass index (BMI), to determine the improvement attributable to GLP1a exposure. Read the full abstract: https://www.auajournals.org/doi/10.1097/01.JU.0001110004.96669.db.06
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