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Purple Mangosteen is a food supplement that helps accelerate metabolism and lipolysis (the process of breaking down body fat). Purple Mangosteen also decreases your appetite which empowers you to consume less food without feeling hungry and weak. The extract of Purple Mangosteen, also called Garcinia Mangostana, also has a beneficial effect on decreasing cholesterol levels. The regular use of Purple Mangosteen is a highly effective way to clean toxins from the body, boost metabolism, and improve the better functioning of internal organs. Find out how to lose weight in a natural & easy way at https://www.purple-mangosteen.com

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Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age, affecting around 5-10% of this population. It is characterized by hormonal imbalances, irregular menstrual periods, and the development of small cysts on the ovaries. One of the most challenging symptoms of PCOS is weight gain and difficulty in losing weight. Women with PCOS often struggle with obesity and related complications such as insulin resistance, type 2 diabetes, and cardiovascular disease. Traditional weight loss methods like diet and exercise may not always be effective in managing weight in PCOS patients. However, recent studies have shown promising results with the use of semaglutide, a medication typically used for type 2 diabetes, in helping PCOS patients achieve weight loss.

Semaglutide and PCOS Weight Loss

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by mimicking the effects of the naturally occurring hormone GLP-1. It helps regulate blood sugar levels, suppresses appetite, and promotes satiety, leading to reduced calorie intake and weight loss. In recent years, semaglutide has gained attention for its potential in managing weight in individuals with obesity and related conditions, including PCOS.

A randomized controlled trial published in the Journal of Clinical Endocrinology & Metabolism in 2020 investigated the effects of semaglutide on weight loss in women with PCOS. The study found that participants who received semaglutide injections lost significantly more weight compared to those who received a placebo. The results highlighted the potential of semaglutide as a promising treatment option for weight management in PCOS patients.

Mechanism of Action

Semaglutide works by increasing insulin secretion, decreasing glucagon secretion, slowing gastric emptying, and reducing food intake through its effect on the central nervous system. The medication binds to GLP-1 receptors in the pancreas, brain, and other tissues, regulating glucose metabolism and energy balance. By modulating these pathways, semaglutide helps individuals with PCOS achieve weight loss and improve metabolic parameters.

Additionally, semaglutide has been shown to improve insulin sensitivity and reduce inflammation, both of which are important factors in the management of PCOS. Insulin resistance is a common feature of PCOS, leading to elevated insulin levels, increased androgen production, and ovulatory dysfunction. By targeting insulin resistance and inflammatory pathways, semaglutide can address underlying metabolic abnormalities and promote weight loss in PCOS patients.





Clinical Considerations

Before starting treatment with semaglutide, PCOS patients should undergo a thorough medical evaluation to assess their overall health status and individual treatment goals. Semaglutide is typically administered as a once-weekly subcutaneous injection, gradually increasing the dosage to minimize side effects and maximize weight loss benefits. Patients may experience gastrointestinal symptoms such as nausea, vomiting, and diarrhea, which usually improve over time as the body adjusts to the medication.

It is essential for PCOS patients to work closely with healthcare providers, including endocrinologists, gynecologists, and nutritionists, to develop a comprehensive treatment plan that includes lifestyle modifications, dietary changes, and regular monitoring of metabolic parameters. Semaglutide should be used as part of a holistic approach to weight management in PCOS, focusing on long-term sustainability and overall health improvement.

Future Directions

Research on semaglutide and its role in weight management in PCOS patients is ongoing, with several clinical trials currently underway to further explore its efficacy and safety. As our understanding of PCOS and its metabolic consequences continues to evolve, semaglutide and other GLP-1 receptor agonists may emerge as key therapeutic options for addressing weight gain and related complications in women with PCOS. By integrating pharmacological interventions with lifestyle modifications and personalized care, healthcare providers can better support PCOS patients in achieving sustainable weight loss and improving their overall quality of life.

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#HormoneBalance #SleepToShred #BurnFatNotMuscle #SustainableWeightLoss #ShredSmart #MetabolicHealth #FatLossTips #BodyRecomp #LoseFatKeepMuscle #HolisticFitness #BurnMoreCalories #FatBurningMode #NoMoreCrashDiets #BalancedLiving #CutTheFat #ScienceBasedFitness #SmartShredding #FitnessFacts #FatBurnSecrets #SmartFatLoss

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100% Free Access to SuppCo at http://supp.co/thomas This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like this that we are able to provide the content that we do for free. Click HERE to Subscribe: https://www.youtube.com/c/ThomasDeLauerOfficial?sub_confirmation=1 Please check out the new Shorts channel, DeLauer Clips and Workouts, here: https://www.youtube.com/channel/UCQPQImPsw74KhO0Zy2-leyA/videos Please Subscribe to my Email Newsletter Here: https://www.thomasdelauer.com/life-optimization-tactics/ Follow More of My Daily Life on Instagram: http://www.Instagram.com/ThomasDeLauer References https://pmc.ncbi.nlm.nih.gov/articles/PMC6683029/ Timestamps ⏱ 0:00 - Intro 1:20 - 100% Free Access to SuppCo 2:42 - GLP-1 & MCT Oil 6:30 - When to Consume

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Sign up for the Beginner's Guide to a Fasting Lifestyle course: http://bit.ly/3OFiIgy OPEN ME 👇 FOR RESOURCES MENTIONED ►Sign up for the FTW to get your companion guide: https://bit.ly/3tw7Sk8 ►Join the Reset Academy: https://bit.ly/3Iu9yzB ►Give Like a Girl: https://drmindypelz.com/glag ►Fast Like a Girl: https://hayhs.com/flag_pp_hc_az ►Fast Like a Girl Journal: https://bit.ly/441qiaV ►Order Eat Like a Girl: https://hayhs.com/elag_pp_hc_az ►The Menopause Reset: https://hayhs.com/mr_pp_pb_az ►Books: https://drmindypelz.com/books ►Fast Like a Girl Certified Coaches: https://drmindypelz.com/flag-certified-coaches NOTES: A 2000 study in the New England Journal of Medicine found that people gain an average of 1-2 pounds of fat during the holidays each year. A 2023 study in JAMA found similar results: weight gain increased sharply during the holidays. Weight gain was unevenly distributed across the population. Some people didn’t gain weight at all, while others gained up to 4% of their body weight (2-5 pounds for most people). Alternate Day Fasting (ADF) A 2023 review in Obesity compared weight loss in people doing regular dieting, ADF, 5:2 fasting, and daily intermittent fasting. All types of fasting worked better than regular dieting. ADF was the best type of fasting for weight loss—better than 5:2 and daily IF, though those both worked well too. A 2017 study in JAMA had participants do either ADF or regular low-calorie dieting for 12 months. The ADF group lost about 20% more weight than the normal dieting group. However, the ADF group also had a 9% higher dropout rate—suggesting that ADF may be difficult to stick to long-term for some people. That’s why it’s important to train your body with shorter fasts and get used to ADF. It’s a more advanced form of fasting. 36-Hour Fasting A 2023 study in Frontiers in Cardiovascular Medicine found that a single 36-hour fast dramatically improved blood lipids, a marker of heart health and longevity. A 2022 review in Disease Markers notes that 36-hour fasting is better than shorter fasts at stabilizing blood sugar and shifting the body into deep ketosis. REFERENCES: https://pmc.ncbi.nlm.nih.gov/articles/PMC4336296 https://pmc.ncbi.nlm.nih.gov/articles/PMC10375309 https://pubmed.ncbi.nlm.nih.gov/36349432 https://pmc.ncbi.nlm.nih.gov/articles/PMC11085973 https://pmc.ncbi.nlm.nih.gov/articles/PMC10513913 https://pmc.ncbi.nlm.nih.gov/articles/PMC8754590 **** Let's be friends! Facebook: https://www.facebook.com/drmindypelz Facebook Group: https://www.facebook.com/groups/resetters Instagram: https://www.instagram.com/dr.mindypelz Tiktok: https://www.tiktok.com/@drmindypelz The Resetter Podcast: Apple Podcast: https://podcasts.apple.com/us/podcast/the-resetter-podcast-with-dr-mindy-pelz/id1503897906 Spotify: https://open.spotify.com/show/6j6ML4pYocMLahMODUtYt5 Affiliate Disclaimer https://drmindypelz.com/affiliate-disclosure ***** Please note the following medical disclaimer: By viewing this video you understand that this video is for educational purposes only. It is not intended to substitute for professional medical advice and should not be relied on as health or personal advice. Always seek the guidance of your doctor with any questions you may have regarding your health or medical condition. You also understand and agree that the terms of our Privacy Policy and Terms of Service apply to your interaction with us.

Lunch Recipe For Weight Loss Day 19 Weightlossrecipes Weightloss Vimalavangala