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Revolutionizing Obesity Treatment: Connecticut's Bold Move and Pharma's Power Plays In this episode of The Downsize News, dated Monday, July 14th, hosts Laraine and Christopher Durham delve into groundbreaking developments in the world of GLP-1 medications, which have significantly impacted their personal weight loss journeys. They start with Connecticut's recent legislative move to manufacture generic versions of GLP-1 drugs, pending federal approval, aimed at reducing costs and expanding access. This could set a precedent for states like California, Louisiana, Washington, North Carolina, West Virginia, and Pennsylvania amidst skyrocketing GLP-1 expenditures. Next, Novo Nordisk's aggressive marketing campaign for Wegovy during the NBA finals is highlighted, alongside this pharmaceutical giant's bid for a higher dose approval in Europe. This newer dose has shown substantial promise in clinical trials, potentially signaling further advancements for US markets. Eli Lilly, in a defensive maneuver, is increasing its US imports from Ireland to buffer against potential trade disruptions, illustrating the global implications of GLP-1 drug production and distribution. Additionally, Novo Nordisk's $2.3 billion investment in Italian manufacturing marks its effort to maintain a competitive edge in the European market. Other stories include promising preclinical studies on the new combination drug Cagrisema, which merges amylin analog with Semaglutide, showing enhanced weight loss mechanisms that counter normal metabolic adaptation. Kate Farms' introduction of a new high-protein, zero-sugar nutritional shake and Ipsos' innovative 'GLP-1 Persona Bot' for better consumer insights underscore the market's evolving landscape. Eli Lilly's donation of a mobile clean room lab to Purdue University aims to train future professionals in sterile compounding, crucial for advancing pharmaceutical manufacturing. The episode wraps up with the Durhams urging viewers to visit their Amazon store for curated GLP-1 user products, supporting both their channel and the weight loss journey of their community. DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store As an Amazon Associate I earn from qualifying purchases. DOWNSIZED WEBSITE: https://thedownsized.org/ BOOK THE DOWNSIZED AT SEA CRUISE 2026: https://thedownsized.org/downsized-at-sea-2026/ JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ 00:00 Introduction and Overview 01:18 Connecticut's Bold Move on GLP-1 Generics 06:34 Novo Nordisk's Wegovy Ad Blitz 10:21 Novo Nordisk Submits Higher Dose Wegovy to EU 13:03 Eli Lilly's Strategic Moves 15:13 Novo Nordisk's Expansion in Italy 16:53 Preclinical Study on Cagrisema and Weight Loss 20:07 Novo Nordisk's Investment in China 23:03 Kate Farms' New High-Protein Shake 23:59 Ipsos' GLP-1 Persona Bot 26:11 Eli Lilly's Mobile Clean Room Lab Donation 27:41 Conclusion and Final Thoughts

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This video explains how to do intermittent fasting for fat loss. If you're looking for an intermittent fasting diet for fast weight loss you got to check this video out. Everything you need to start an intermittent fast is explained and benefits are included. 🔥 FREE 6 Week Shred: https://GravityTransformation.com 📲 Diet/Workout Calculator: http://bit.ly/2qw2JbB Intermittent fasting is becoming more more popular and there is a lot of information out there on the topic but what I intend to do today is really simplify all of this information for you into one easy-to-follow guide. And what I would really like for you to get out of this video would be the principles behind why intermittent fasting works so you can apply it to your diet in a flexible way. So what is intermittent fasting? It's a way of structuring your eating plan in which you spend a portion of time not eating anything at all and then that's followed by a portion of time in which you can eat quite a bit more then usual. There are a bunch of popular ways to setup your feeding and fasting Windows. For example the lean gains otherwise known as the 16/8 method is one of the most popular approaches. Here you would spend 16 hours of the day fasting and then you would use the other eight hours of the day as you're feeding window. In this method it's usually popular to just skip breakfast and curb your appetite with some coffee and sparkling water. Then there's another one called The Warrior Diet. Here it's recommended to have an 18 to 20 hour fast and then a four to six hour feeding period. Another method is the alternate day fast. Here you would fast for one day and then eat more of what you wanted the next day. And the last one that I want to mention in this video is the 5-2 diet which is a form of intermittent fasting in which you spend two days at a very low deficit like under 25% of maintenance and then 5 days of eating normally. Now the crazy thing is, that even though these methods are pretty different from each other they can all work. So what does this tell us about intermittent fasting? Does this tell us that we can eat whatever we want during our feeding windows and still burn fat just because we fasted. Not exactly. The reason why all of these different intermittent fasting plans work is because by having a period of time in which you don't allow yourself to eat very many calories you are likely creating a calorie deficit. In case you don't know what that means a calorie deficit is when you take in less calories then your body needs to maintain its daily functions. This lack of energy causes your body to pull energy from your fat stores to make up for what it's not getting from your diet. It's literally that simple. Combine this with the fact that when you eat all your food in one to two meals you can only eat so much before you start to feel full and that will create even better conditions for an overall caloric deficit. Now the reason why this doesn't mean that you could eat whatever you want to whatever excess you want is because if you eat so much that you take away that caloric deficit then you won't lose weight. In fact if during your feeding period you eat so much that you put yourself into a state of a caloric Surplus then you may even put on fat on an intermittent fasting plan. This is the thing that is often times misunderstood and neglected by many people that start an intermittent fasting protocol. What intermittent fasting does do for you is by limiting your eating only to a smaller period of the day you save calories and have more room 4 more of those calories to be consumed at once. If for example you're only eating two meals in the day you're going to be able to eat a lot more calories during those two meals. Which gives you more room to eat higher calorie foods like junk food for example. Pretty much a good way to sum up most intermittent fasting protocols is to eat larger meals less frequently. Now that's not taking anything away from the effectiveness of these plans. I just want you guys to understand the bottom line behind why they work. Because if you can understand that then you don't need to be bound to any kind of one diet not even intermittent fasting. Your diet can be more adaptive based on your life and it could work for you rather than something that you have to obsess over. The whole point of intermittent fasting is for us to see that obsessing over meal frequency and losing muscle mass and about our diet in general is unnecessary to have success. However you see a lot of people doing intermittent fasting obsessing 🔥 FREE 6 Week Shred: https://GravityTransformation.com