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13 Reasons Why You Are Not Losing WEIGHT on GLP-1 Drugs?! Why Ozempic, Mounjaro, or Wegovy Might Not Be Working for You and are you using Ozempic, Mounjaro, Wegovy, or other GLP-1 weight loss injections—but the scale just won’t budge? You’re not alone. Millions are turning to semaglutide and tirzepatide injections for weight loss… but up to 1 in 5 people see little to no results. In this video, we break down 13 overlooked reasons why your GLP-1 medication might not be working the way you expected. Whether you're taking Ozempic for weight loss, Mounjaro for obesity, or Wegovy for fat loss, this guide uncovers what could be silently sabotaging your progress. 🔍 What you'll learn in this video: Why Ozempic or Mounjaro might stop working suddenly? The truth behind GLP-1 weight loss plateaus, Critical mistakes in sleep, stress, diet, and dosage that slow your fat loss. How lifestyle, not just the GLP-1 injection, determines your long-term success. The link between Ozempic side effects, protein intake, and metabolic health and what to do if you’re a non-responder to semaglutide or tirzepatide. 💉 These insights go beyond just injections—they’re the missing piece for anyone serious about lasting transformation. From Ozempic face concerns to Mounjaro weight loss before and after tips, we’re giving you the full picture. ⚠️ If your weight loss has stalled—or never started—this video gives you the tools to reset and reignite your progress. 📲 Subscribe for more honest, science-backed health content without the fluff. 💬 Drop a comment if one of these reasons hit home—or helped you break a plateau. 🔁 Share this with someone on the GLP-1 journey who needs a breakthrough. #ozempic #ozempicweightloss #ozempicjourney #ozempicsideeffects #glp1 #glp1support #glp1weightloss #glp1community #mounjaro #wegovy #zepboundweightloss #zepbound #semaglutide #saxenda **Disclaimer: The content in this video is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Weight loss is a common goal for many individuals looking to improve their overall health and well-being. However, achieving and maintaining weight loss can be a challenging task for some. This is where weight loss medications, such as Semaglutide, come into play. Semaglutide is a relatively new medication that has shown promising results in helping individuals lose weight effectively. In this article, we will explore everything you need to know about Semaglutide, how it works, its potential side effects, and more.
How Does Semaglutide Work?
Semaglutide is a medication that belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. GLP-1 is a hormone that is naturally produced in the body and plays a role in regulating blood sugar levels and appetite. By mimicking the actions of GLP-1, Semaglutide can help promote weight loss in several ways. Firstly, Semaglutide can decrease appetite and increase feelings of fullness, leading to reduced food intake. Additionally, Semaglutide can slow down the emptying of the stomach, which can help individuals feel fuller for longer periods.
Furthermore, Semaglutide can also increase the body’s sensitivity to insulin, which can help improve blood sugar control in individuals with diabetes. This can be beneficial for individuals who struggle with weight loss due to insulin resistance.
In clinical trials, Semaglutide has been shown to significantly aid in weight loss when combined with a reduced-calorie diet and increased physical activity. Many individuals have seen substantial weight loss results with Semaglutide compared to a placebo group.
Potential Side Effects of Semaglutide
As with any medication, Semaglutide can cause potential side effects in some individuals. Common side effects of Semaglutide may include nausea, vomiting, diarrhea, constipation, abdominal pain, and decreased appetite. These side effects are usually mild and tend to improve over time as the body adjusts to the medication.
In rare cases, more serious side effects may occur with Semaglutide use. These can include pancreatitis (inflammation of the pancreas), gallbladder problems, kidney damage, and allergic reactions. It’s essential to discuss any concerns or potential side effects with your healthcare provider before starting Semaglutide.
It’s also crucial to note that Semaglutide is not suitable for everyone. Individuals with a history of pancreatitis, thyroid tumors, or multiple endocrine neoplasia syndrome type 2 should not take Semaglutide. Additionally, pregnant or breastfeeding women should avoid Semaglutide use due to potential risks to the fetus or infant.
How to Take Semaglutide
Semaglutide is typically administered as a once-weekly injection either under the skin of the abdomen, thigh, or upper arm. The dosage of Semaglutide can vary depending on the individual’s weight loss goals and overall health. It’s essential to follow your healthcare provider’s instructions carefully when taking Semaglutide to ensure safe and effective use of the medication.
It’s also recommended to combine Semaglutide treatment with a reduced-calorie diet and increased physical activity to maximize weight loss results. Regular follow-up appointments with your healthcare provider are essential to monitor your progress and adjust your treatment plan as needed.
If you miss a dose of Semaglutide, it’s essential to take the missed dose as soon as you remember, unless it’s close to the time for your next dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double dose to make up for a missed dose.
FAQs About Semaglutide
Q: How much weight can I expect to lose with Semaglutide?
A: The amount of weight loss with Semaglutide can vary depending on the individual. However, clinical trials have shown that individuals taking Semaglutide can achieve significant weight loss compared to a placebo group.
Q: Is Semaglutide a permanent solution for weight loss?
A: Semaglutide is not a permanent solution for weight loss. It is essential to adopt healthy lifestyle changes, such as a balanced diet and regular exercise, to maintain weight loss results achieved with Semaglutide.
Q: Are there any drug interactions I should be aware of when taking Semaglutide?
A: It’s essential to inform your healthcare provider of all medications, supplements, and vitamins you are taking before starting Semaglutide. Some medications may interact with Semaglutide and affect its effectiveness or increase the risk of side effects.
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Considering GLP-1s for Weight Loss? Find Out How to Avoid Muscle Loss or Muscle Wasting with GLP-1 Semaglutides. Thinking about using Ozempic, Wegovy, Zepbound, or Mounjaro for weight loss but not sure if they cause muscle loss or muscle wasting along with burning fat? Curious why drug companies are doubling down on clinical trials focused on preserving lean muscle in addition to fat loss like new GLP-1 medications Retatrutide and CagriSema now in trials? Before you start, it’s critical to understand how GLP-1 drugs affect lean muscle mass, especially for women over 40. Research shows up to 40% of weight lost with semaglutide can come from muscle—not just fat. And that’s a problem for your metabolism, strength, and long-term health. In this video, I break down & answer the questions: - The real risk of muscle loss on GLP-1s - Does ozempic cause muscle loss? Is semaglutide muscle wasting real? - How to tell if you're losing fat or lean mass - Why Wegovy muscle loss or Zepbound muscle loss is a big deal. - Do you lose fat or muscle on ozempic - Why this matters more during perimenopause and menopause - The strength training and protein strategies I use with women over 40 on GLP-1s - How to approach weight loss without losing what makes your body strong I don’t cover the new GLP-1 weight loss drugs in clinical trials—like Retatrutide, CagriSema, or semaglutide + myostatin blockers—in depth, but if you’re considering medications like Ozempic, Wegovy, or Mounjaro, or want to understand the risks of muscle loss and metabolic slowdown, this is where to start. As an IFBB Fitness Pro and women’s fitness coach, I’ve helped thousands of women lose fat, build muscle, and feel confident in their bodies—without extremes. ✅ What you’ll learn: Fat loss vs. muscle loss on GLP-1s Signs you’re losing strength, not just weight Protein + strength training tips for women 40+ A smarter weight loss approach with long-term results WATCH NEXT: My 5 Secrets to Get Fit Over 40 - Science Backed Hacks https://youtu.be/Wjdp1NHmjqM?si=8Xp-On7hd361IESz Overnight Protein Oats Recipe: 29g Protein for Busy Mornings https://youtu.be/W-xFOVQDsws Cover Model Ab Secret Revealed: EASY Move for a Flatter Belly https://www.youtube.com/watch?v=dxZB8h95c0Y&list=PLr_YQSGJumkOgV9TgtzlU0raLJCwNe6eq&pp=gAQBiAQB 🔥 Top 5 Fat-Burning Barbell Moves | Compound Exercises to Lose Fat! https://youtu.be/id3PfAPY1-U?si=g4F8jIyBdquR_6Zo FOLLOW ME 📩 FREE FITBODY MAGAZINE: https://fitbodymagazine.com/ ℹ️ WEBSITE: https://julielohre.com/ 🏆 COACHING: https://julielohre.com/online-personal-training/ 💪 SUPPLEMENTS: http://fitbody.com/ 🎧 PODCAST: https://julielohre.com/fitbody-podcast/ 🏋️ EXERCISE LIBRARY: https://julielohre.com/exercise-library/ 00:00 Are GLP-1s Making You Skinny Fat? 00:20 Why You Might Be Losing Muscle with Zepbound and Wegovy 01:00 Real Talk: Support, Not Shame 01:45 What Is 'Skinny Fat'? 03:00 The Hidden Problem with Muscle Loss 04:15 It’s Not Just About Looks—It’s About Health 05:30 How GLP-1 Medications Work 06:45 Research: 40% of Weight Loss = Muscle 08:00 Why This Matters More for Women Over 40 09:00 Menopause, Estrogen, and Muscle Decline 10:15 Fat Loss vs. Weight Loss—The Big Shift 11:00 Strategy 1: Strength Training Is Non-Negotiable 12:20 Strategy 2: Protein Intake Targets for Women Taking Semaglutides 13:40 High-Protein Meal Ideas for Low Appetite 14:20 Strategy 3: Prioritize Recovery and Movement 15:00 Stop Obsessing Over the Scale 16:00 What to Track Instead of Just Weight 16:50 The Bottom Line: Stay Strong, Not Just Smaller 17:30 How I Can Help You Lose Fat & Build Muscle Bikou, Athanasia, et al. “A Systematic Review of the Effect of Semaglutide on Lean Mass: Insights from Clinical Trials.” Expert Opinion on Pharmacotherapy, vol. 25, no. 5, Apr. 2024, pp. 611–619. https://pubmed.ncbi.nlm.nih.gov/38629387/ Møller, N., et al. “Changes in Lean Body Mass with Glucagon‑Like Peptide‑1‑Based Therapies.” Diabetes, Obesity and Metabolism, 2024. https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.15728 Tamborlane, W. V., et al. “Weight Loss and Body Composition Outcomes with Once‑Weekly Semaglutide.” Journal of Clinical Endocrinology & Metabolism, vol. 109, no. 3, 2022, pp. 704–713. https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.16162 https://www.drugdiscoverytrends.com/glp-1-impact-lean-mass/ Latif, Wafa, Katerina J. Lambrinos, and Rolando Rodriguez. “Compare and Contrast the Glucagon‑Like Peptide‑1 Receptor Agonists (GLP1RAs).” StatPearls, StatPearls Publishing, 27 Mar. 2023. https://www.ncbi.nlm.nih.gov/books/NBK572120/ Massachusetts General Brigham. “Preserving Lean Body Mass in Patients Taking GLP‑1 for Weight Loss.” Endocrinology Advances in Motion, 6 June 2025. https://advances.massgeneral.org/endocrinology/article.aspx?id=1601
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