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【今回の動画の内容】肥満症と糖尿病の薬「GLP-1/GIP製剤」について糖尿病専門医による解説動画になっています。後編も合わせてご覧ください。 【目次】 0:00 ダイジェスト 1:13 GLP-1/GIPってなに？ 4:28 GLP-1/GIP製剤の歴史　 7:20 GLP-1/GIP製剤の比較 9:37 オゼンピック、マンジャロについて 16:50 GLP-1/GIP製剤の副作用 19:44 動画のまとめ 【動画の内容に関するお願い】 動画の内容は一般的な内容であり、全ての方に当てはまるものではありません。 個々の気になる症状や治療法については、必ず主治医にお尋ねください。 動画に対するご意見は是非ともコメント欄に記入下さい。 【ご案内】 にしな内科・糖尿病内分泌クリニック公式チャンネルでは、糖尿病や甲状腺などの内科疾患に関する情報発信を行っています。チャンネル登録を頂くと本チャンネルの動画が閲覧しやすくなります。また🔔通知ボタンをONにして頂くと最新の動画がアップされた際に通知が届きます。 チャンネル登録はこちら！ ⇒　www.youtube.com/@nishina-clinic.amagasaki にしな内科・糖尿病内分泌クリニック公式HP ⇒ https://nishina-clinic.jp/ オンライン予約はコチラ　⇒　https://h.inet489.jp/nishinacl/yoyaku/login.cgi?recno=&birth= 前回の動画：https://www.youtube.com/watch?v=7qw7lbUlCgU 　糖尿病の合併症ってなに？～糖尿病腎症編～ ＜院長略歴＞ 2011年　神戸大学医学部卒業 2011年〜　近畿中央病院で初期臨床研修医課程　 2013年〜　日本生命済生会付属日生病院　後期研修医課程 2016年〜　大阪大学医学部附属病院 糖尿病内分泌代謝内科で病棟医として勤務 2017年〜　関西労災病院 内科 医長、大阪大学医学部附属病院にて内分泌専門外来診療 2021年～　にしな内科・糖尿病内分泌クリニック　開院 ＜資格＞ 日本内科学会認定内科医・総合内科専門医 日本内科学会総合内科専門医 日本糖尿病学会糖尿病専門医 日本内分泌学会専門医 【にしな内科・糖尿病内分泌クリニックについて】 にしな内科・糖尿病内分泌クリニック公式HP ⇒ https://nishina-clinic.jp/ 住所：兵庫県尼崎市七松町1-2-1 301A フェスタ立花北館3階 電話：06-6411-1011 FAX：06-6411-1012 ネット予約が可能です ⇒　https://h.inet489.jp/nishinacl/yoyaku/login.cgi?recno=&birth= Instagram ⇒ https://www.instagram.com/nishina_naika_/

This Man Proves That Losing Weight Is Easy

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Oprah Winfrey has been a household name for decades, known for her successful talk show, media empire, and philanthropic efforts. Always at the forefront of trends and movements, Oprah recently made headlines for her venture into the popular ketogenic diet. Known for its high-fat, low-carb approach, the keto diet has gained a following for its potential weight loss and health benefits. Oprah’s decision to try the keto lifestyle has sparked curiosity and discussion in the health and wellness community. Let’s take a deep dive into Oprah’s keto philosophy and explore how she approaches this trending diet.

Oprah’s Initial Skepticism

When Oprah first heard about the keto diet, she admits to being skeptical. Like many people, she was wary of the high-fat aspect of the diet, fearing it would be detrimental to her health. However, after doing extensive research and consulting with experts, Oprah began to see the potential benefits of the keto lifestyle. She learned that the diet could help improve energy levels, focus, and even aid in weight loss. With an open mind, Oprah decided to give the keto diet a chance.

As she embarked on her keto journey, Oprah encountered some challenges and adjustments. The drastic reduction in carbs forced her to rethink her approach to meals and snacks. Oprah had to experiment with new recipes and food combinations to ensure she was getting the right balance of fats, proteins, and carbs. Despite the initial hurdles, Oprah was determined to stay the course and see if the keto diet could live up to its promise of health and wellness benefits.

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One of the key aspects of Oprah’s keto philosophy is balance. While the diet is high in fats, Oprah believes in the importance of choosing healthy fats from sources like avocados, nuts, and olive oil. She emphasizes the need to nourish the body with nutrient-dense foods while still enjoying the indulgences that make life enjoyable. Oprah understands that sustainability is crucial for any diet to be successful, so she focuses on finding a balance that works for her lifestyle and preferences.

Embracing a New Mindset

For Oprah, the keto diet is more than just a way to lose weight or improve health. It represents a shift in mindset towards wellness and self-care. Oprah views the keto lifestyle as a journey of self-discovery and personal growth. By paying attention to what she puts into her body and how it affects her overall well-being, Oprah has found a newfound appreciation for the connection between food and health.

Another important aspect of Oprah’s keto philosophy is listening to her body. She practices mindful eating, tuning into her hunger cues and cravings to guide her food choices. Oprah believes in the power of intuition when it comes to nourishing the body and strives to make choices that align with her physical and emotional needs. This holistic approach to eating allows Oprah to feel more in tune with her body and make conscious decisions about her health.

As Oprah continues her keto journey, she remains committed to sharing her experiences and insights with her audience. Through her platform and media channels, Oprah opens up about the challenges and successes of following the keto diet. She encourages others to explore different paths to wellness and find what works best for their bodies. Oprah’s transparency and authenticity inspire others to embrace a health-focused mindset and prioritize self-care in their own lives.

Looking to the Future

As Oprah delves deeper into the keto lifestyle, she looks towards the future with optimism and curiosity. She sees the diet as a tool for ongoing health and wellness, helping her to maintain energy, focus, and vitality as she continues to pursue her passions and goals. Oprah’s commitment to self-improvement and personal growth extends to her approach to diet and nutrition, where she aims to foster a healthy relationship with food and her body.

Ultimately, Oprah’s venture into keto represents a journey of exploration and empowerment. By embracing a new way of eating and thinking about food, Oprah is not only taking control of her health but also setting an example for others to follow. Through her authenticity and willingness to share her experiences, Oprah invites her audience to join her on the path to wellness and discover the transformative power of the keto lifestyle.

In conclusion, Oprah’s venture into the keto diet offers a unique perspective on wellness, self-care, and personal growth. Her thoughtful approach to the keto lifestyle highlights the importance of balance, mindfulness, and listening to one’s body. As Oprah continues on her journey, she serves as an inspiration for others to explore new paths to health and well-being. Whether you’re curious about the keto diet or simply looking for motivation to prioritize your health, Oprah’s keto philosophy is a compelling story of transformation and empowerment.

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✅ Get The Recipe Now: https://hotm.art/Recipe_Turmeric- ✅ Get The Recipe Now: https://hotm.art/Recipe_Turmeric- TURMERIC HACK FOR WEIGHT LOSS⚠️(FULL RECIPE!) TURMERIC HACK RECIPE - WHAT IS TURMERIC TRICK? The Turmeric Hack: Harvard-Backed Weight Loss Secret Going Viral on TikTok Millions are turning to a simple yet powerful solution for weight loss—the Turmeric Hack. This science-backed approach, endorsed by Harvard studies, leverages turmeric’s potent properties to boost metabolism, burn fat, and enhance overall vitality. With its viral success on TikTok, users are raving about its rapid and noticeable effects. What is the Turmeric Hack? The Turmeric Hack revolves around curcumin, turmeric’s active compound, which is clinically proven to aid in fat burning, digestion, and blood sugar regulation. Researchers from Harvard highlight turmeric’s anti-inflammatory and metabolic-boosting benefits, making it an effective and natural weight loss strategy. Proven Benefits of the Turmeric Hack ✔ Boosts Fat Burning – Activates metabolism and supports natural fat loss. ✔ Controls Appetite – Reduces cravings and prevents binge eating. ✔ Regulates Blood Sugar – Helps maintain stable energy levels throughout the day. ✔ Reduces Inflammation – Lowers chronic inflammation linked to weight gain. ✔ Scientifically Backed & Viral – Gaining massive popularity on TikTok with real-life success stories. How to Use the Turmeric Hack For optimal results, mix a teaspoon of turmeric powder with hot water, coffee, or tea, and drink it daily. For enhanced absorption, combine it with black pepper or a healthy fat like coconut oil. Many TikTok users swear by the "7-second Turmeric Hack" for quick and effortless weight loss. Popular Turmeric Hack Recipes 💛 Morning Metabolism Booster – Add turmeric to your coffee for an energizing start. 💛 Fat-Burning Detox Drink – Mix turmeric with warm water, lemon juice, and honey. 💛 Golden Smoothie – Blend turmeric with almond milk, ginger, and cinnamon. Viral Success & Real Results The Turmeric Hack is taking over TikTok and social media, with thousands sharing before-and-after transformations. Whether you’re aiming for steady weight loss or a metabolic boost, this Harvard-backed method is a natural, simple, and effective solution. 🚀 Try it today and experience the proven power of turmeric! #turmerichack #turmerichackrecipe #turmerichackforweightloss #harvardturmerichack #turmericweightlossviral

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Cycling is the BEST weight loss aka fat burning exercise around. Heck, its not even exercise when you make it a LIFESTYLE like riding to work, riding with your kids, riding to do errands etc. The BEST most dramatic weight loss transformations I have seen is when an individual be it male or female, younger or older grabs the high carb low fat vegan fruit focused lifestyle by the handle bars and jumps on a nice crisp new properly fitted road bike and pedals off into the horizon. Literally. Ive done lots of videos on the benefits for health & weight loss on a high carb low fat raw foods style vegan lifestyle. When you focus just on diet you miss out on the other VITAL facets involved in PERMANENT weight loss. What are these vital fat burning lifestyle tips? Its early nights, drinking enough for clear urine, doing b12 shots if you have low levels etc. Its eating high calories from whole food plant carbs with fruit being the BEST. Why high calorie? So you ALWAYS have enough glycogen to live the adventure!! Why low fat? So your not suffering form lipidemia and having 'heavy legs' and losing motivation and having to rely on caffeine like so many of low carb paleo diet primal diet low carb diet noobs do. SMASH in the carbs like its your last meal on earth. Keep it low sodium, high carb, low fat NO OIL NO ANIMAL PRODUCTS and enjoy the good times ahead. Thanks for watching. Leave your comments down below. If you liked the content please subscribe: http://www.youtube.com/subscription_center?add_user=durianreider My channel: http://www.youtube.com/user/durianreider/featured Sleep, water, sugar sufficiency must be the daily focus. Sun + sport must be the weekly focus. Making the world a better place for humanity, the animals and the environment must be the life focus. Here are some more tips from Durianrider & Freelee One MUST get consistent early nights to ensure success on a healthy weight loss lifestyle. More early nights means a healthier and faster metabolism + you will have greater nerve energy for the next day as your organs get the rest they need to function healthfully. High carb low fat fruit based lifestyles work wonders for long term weight loss transformations. Ive NEVER seen a fat fruit or rice muncher EVER. People sneak in fat and wonder why they get fat. Im talking FAT FAT not skinny fat cos someone doesnt move their body and they wonder why they dont have a tight stomach.

Weight loss transformation WILL happen when you do the right things. High carb, low fat, early nights, consistent hydration etc. Participate in your fav activities to build the toned body that you want. Its easy to lose weight but to build a toned body you MUST MOVE IT! :) AND eat enough carb calories so that the active adventure filled lifestyle is EASY to maintain!! So many people make the mistake of not eating enough carb calories DAILY!! Thats like wanting to be a big spender on 5$ a day! CHOW DOWN THE CARB CALORIES REGARDLESS OF YOUR WEIGHT!! My recommendations for anyone wanting to get fit + stay fit + gain muscle + burn fat is 10g of carbs per kg of bodyweight per day MINIMUM (even on days off) and 1g of carbs per kg of bodyweight per hour when you're out training. I personally drink enough water so Im pizz'n at least 10 times a day CLEAR and a few times a night. If my urine is yellow or straw, I just knock back a quart and Im good to go. Raw food diet vegan high carb low fat style based on fruit keeps you slim naturally. How to get a flat stomach, how to lose weight with raw foods.how to start a raw food diet? all these questions and more answered by Durianrider & Freelee on our channels. Thanks for watching! :) I am NOT Harley / Durianrider or Freelee, I simply support their cause. If you wish to visit his channel please go to http://www.youtube.com/user/durianriders/ http://www.youtube.com/user/Freelea or show support on his facebook page at https://www.facebook.com/pages/Durianrider/197363716986830 He gave explicit permission to re-upload this content. YOUTUBE / GOOGLE EMPLOYEES PLEASE NOTE Durianriders gave a statement on facebook regarding free upload and use of his content to spread the message: https://www.facebook.com/permalink.php?story_fbid=397764540280079&id=1973... Youtube video confirming the same: http://youtu.be/4FPNsOs9zsA You rock Durianrider!

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In this episode of The Beyond Face Value Show, Dr. Jill Wade and guest co-host Laura Lewis Edwards dive into the fascinating world of Ozempic and other GLP-1 medications. Known for their role in treating diabetes, these groundbreaking medications are now being recognized for their broader health benefits—including weight loss, improved metabolic health, and potential impacts on overall wellness. Whether you’re curious about these medications for managing diabetes, weight loss, or improving your health, this episode provides clear insights and actionable information. 🎧 If you're ready to take a closer look at the evolving role of GLP-1 medications in health and wellness, this episode is for you! Stonebriar Smile Design, founded by general & cosmetic dentist, Jill Wade DDS, is a woman-owned and locally-operated dental practice in Frisco, Texas, committed to revolutionizing how people feel about dentistry. We go above and beyond providing whole health dentistry, and we value long-term relationships with patients so we can guide their overall health in the right direction, starting with oral health. Our team of female dentists in Frisco has over 75 years of combined experience in preventive dentistry, cosmetic dentistry, emergency dentistry, and much more. Dr. Jill Wade and Dr. Jodi Danna use their expertise to push the boundaries of modern dentistry in Frisco and achieve life-changing results. To improve your smile and overall wellness, partner with Stonebriar Smile Design. To learn more about our dental practice located in Frisco, Texas, please visit our website: https://www.stonebriarsmiledesign.com

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🎙️EP282｜善纖達，猛健樂，所有GLP-1受體促效劑：減重、控糖、護心腎？從藥物比較到臨床應用全解析 — 📌主題亮點： • ​ GLP-1受體促效劑的作用機轉是什麼？為何能兼顧控糖與體重管理？ • ​ Tirzepatide、Semaglutide、Liraglutide 怎麼選？療效與副作用比較一次看懂 • ​ 台灣健保給付限制、仿單外使用、心腎保護證據，全方位解析臨床現況 — 🔍內容解析： 本集重點： GLP-1受體促效劑（Glucagon-like peptide-1 receptor agonists, GLP-1 RAs）是目前糖尿病與肥胖症領域中最受矚目的藥物類別之一。這類藥物最初設計目的是控制第二型糖尿病血糖，但其延緩胃排空與降低食慾的機制，逐漸展現出優異的體重控制效果，成為減重治療的重要選項。 本集將全面比較目前臨床上常見的 GLP-1 RAs，包括 Semaglutide、Liraglutide、Dulaglutide、Exenatide、Tirzepatide 等，從作用機制、臨床療效、安全性，到心腎保護與健保給付現況，帶你掌握這波醫藥創新的核心。 — 🧩主題分段解析： — 🧬 GLP-1作用機轉：多重代謝效應的關鍵介質 GLP-1 是人體腸道於進食後釋放的一種腸泌素，具有多重生理功能： • ​ 刺激胰島素分泌（在高血糖狀態下） • ​ 抑制昇糖素分泌 • ​ 延緩胃排空，增加飽足感 • ​ 對中樞神經產生抑制食慾作用 GLP-1受體促效劑則是模擬這一生理訊號的藥物。由於天然 GLP-1 在體內迅速被 DPP-4 分解，因此這類藥物皆經修飾以延長半衰期，使其可每日或每週注射。 ⸻ 🩺 臨床療效比較：控糖與體重減輕雙重奏 根據大型隨機試驗與統合分析，GLP-1 RAs 在控制血糖（HbA1c）與體重管理上皆展現出顯著成效。 📌 各藥物臨床成效對比： 藥物名稱 HbA1c 降幅 體重減輕效果 使用頻率 核准適應症 Semaglutide -1.4 ~ -1.9% -6~15% 每週1次 第2型糖尿病、肥胖（國際核准） Tirzepatide -2.0 ~ -2.4% -10~20% 每週1次 第2型糖尿病（減重待核准） Liraglutide -1.0 ~ -1.5% -5~8% 每日1次 糖尿病、肥胖（Saxenda商品名） Dulaglutide -0.7 ~ -1.5% -2~5% 每週1次 糖尿病 Exenatide -0.8 ~ -1.0% -2~3% 每週或每日 糖尿病 其中 Tirzepatide 屬於 GIP/GLP-1 雙重受體促效劑，在 SURMOUNT 與 SURPASS 試驗中展現出前所未有的血糖控制與減重表現，有望改寫治療標準。 — 💖 心血管與腎臟保護：超越控糖的新方向 越來越多研究指出，GLP-1 RAs 除了降血糖與減重，也具有心腎保護效果，這點在糖尿病病人族群中特別重要。 📌 心血管研究亮點： • ​ LEADER試驗（Liraglutide）： 減少 MACE（重大心血管事件）13% • ​ SUSTAIN-6（Semaglutide）： 顯著降低心血管事件與腎功能惡化風險 • ​ REWIND（Dulaglutide）： 在高風險群中降低中風與心臟衰竭住院率 腎臟方面，GLP-1 RAs 可延緩 eGFR 下降速度、降低蛋白尿發生，與 SGLT2i 一同被納入 CKD 病患用藥建議中（KDIGO 2022）。 — ⚠️ 常見副作用與風險考量 GLP-1 類藥物最常見的不良反應是胃腸道不適： • ​ 噁心、嘔吐、腹瀉（劑量上升時尤明顯） • ​ 厭食、味覺改變 此外，也需注意以下安全議題： 1. ​ 胰臟炎風險： 少見但需警惕，特別是胰臟病史者 2. ​ 甲狀腺 C 細胞腫瘤： 動物實驗有顯示，故有甲狀腺腫瘤病史者應避免使用 3. ​ 低血糖風險： 單用風險低，但與 SU 類或胰島素併用時需留意 4. ​ 腎功能不全： 輕中度 CKD 可使用，但末期腎病需個別評估 目前各大指引皆建議以「緩慢劑量上升」的方式起始治療，以改善耐受性。 — 📋 台灣市場與健保現況：法規限制與臨床建議 雖然 GLP-1 RAs 在國際間已被廣泛應用於肥胖與代謝症候群治療，但在台灣市場仍受到幾項限制： 1. ​ 健保給付範圍有限： 僅核准用於第二型糖尿病患者，且常須 HbA1c ＞ 7.5% 且合併肥胖者 2. ​ 體重管理為仿單外使用： 減重用途目前無正式健保核准 3. ​ 高藥價問題： 自費族群常成經濟負擔障礙 4. ​ 專科醫師使用限制： 多數藥品須由內分泌科或新陳代謝科開立 根據 NHIA 公告，目前 Semaglutide（Ozempic）與 Liraglutide（Victoza）皆列為給付藥品，但需符合嚴格條件。 — 🚶‍♀️ 臨床應用建議：如何選擇最適合的 GLP-1 受體促效劑？ 臨床選擇應考慮以下因素： • ​ 目標： 控糖為主或減重為主？ • ​ 用藥頻率接受度： 每日注射 vs 每週注射 • ​ 腎功能狀況 • ​ 副作用耐受性 • ​ 病患偏好與經濟狀況 📌舉例： • ​ 對減重有高度期待者：Tirzepatide ＞ Semaglutide ＞ Liraglutide • ​ CKD早期患者：Semaglutide、Dulaglutide皆可考慮 • ​ 容易噁心者：可考慮低劑量起始且選擇耐受性較佳者如 Dulaglutide • ​ 自費負擔有限者：評估 Liraglutide 台灣仿單內使用是否適用 — 📣負責任的行動： GLP-1 受體促效劑不只是「減重神藥」，而是結合代謝改善、心腎保護與控糖成效的複合型療法。醫師在使用前應評估患者整體代謝風險、心血管病史與用藥習慣，避免將此藥物視為「萬靈丹」。 病患亦應接受完整衛教，了解可能副作用與正確使用方法，避免自行停藥或過度依賴。 — 📚熱門關鍵字： #GLP1受體促效劑 #Semaglutide #Ozempic #Tirzepatide #Mounjaro #Liraglutide #Saxenda #減重藥物 #糖尿病治療 #心血管保護 #腎臟保護 #胰島素促進劑 #胃排空延緩 #體重管理 #胃腸道副作用 #甲狀腺C細胞腫瘤 #台灣健保給付 #仿單外使用 #慢性腎病新療法 #糖尿病臨床指引 — 🎤主講人資訊： Dr.Happy Human Plumber｜心血管知識推廣者 擅長將複雜代謝藥物與心腎內科整合知識，轉化為清晰易懂的內容，關注台灣臨床處方趨勢與全球新藥發展，致力於提升醫病雙方的治療選擇品質。 Powered by Firstory Hosting (https://firstory.me/zh)