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Semaglutide, a medication that was originally approved to treat type 2 diabetes, has recently gained attention for its effectiveness in promoting weight loss. Clinicians have found that certain formulations of semaglutide can help individuals shed excess pounds when used in combination with diet and exercise. However, not all semaglutide products are approved for weight loss. In this article, we will explore which semaglutide formulations have been specifically approved for weight loss, the brands that offer these products, and the different forms in which they are available.

Approved Semaglutide Products for Weight Loss

One of the most well-known semaglutide products approved for weight loss is Wegovy (semaglutide 2.4 mg), manufactured by Novo Nordisk. This higher-dose formulation of semaglutide has been shown to be effective in helping individuals with obesity or overweight achieve significant weight loss. Wegovy is administered once weekly via subcutaneous injection and is typically prescribed as part of a comprehensive weight management program.

In addition to Wegovy, another semaglutide product approved for weight loss is Rybelsus (semaglutide 7 mg or 14 mg), also produced by Novo Nordisk. Unlike Wegovy, Rybelsus is available in tablet form and is taken orally once daily. Rybelsus is FDA-approved for managing blood sugar levels in adults with type 2 diabetes as well as for weight management in individuals with a BMI of 27 kg/m² or higher.

It is important to note that while semaglutide has shown promising results in promoting weight loss, it is not a standalone solution. Individuals considering semaglutide for weight management should also focus on making healthy lifestyle choices, including following a balanced diet and engaging in regular physical activity.

Brands Offering Semaglutide Products

In addition to Novo Nordisk, other pharmaceutical companies have started developing semaglutide products for weight loss. For example, Eli Lilly and Company recently received FDA approval for a once-weekly injectable semaglutide formulation for weight management. As more manufacturers enter the market with semaglutide products, individuals may have a wider range of options to choose from.





As with any medication, individuals considering semaglutide for weight loss should consult with their healthcare provider to determine the most appropriate treatment plan for their needs. Healthcare providers can help assess the potential benefits and risks of semaglutide therapy and provide guidance on how to optimize its effectiveness.

Forms of Semaglutide for Weight Loss

Semaglutide is available in various forms, including injectable pens, prefilled syringes, and oral tablets. The choice of formulation may depend on individual preferences, lifestyle factors, and healthcare provider recommendations. Injectable semaglutide products are typically administered by the individual themselves, while oral tablets can be taken at home without the need for injections.

Some individuals may prefer the convenience of oral semaglutide tablets, while others may find it easier to stick to a routine with weekly injectable formulations. It is essential for individuals to discuss their preferences and any concerns with their healthcare provider to ensure that they are comfortable with the chosen semaglutide product for weight loss.

Overall, semaglutide has emerged as a promising option for individuals looking to manage their weight effectively. By understanding which semaglutide products are approved for weight loss, the brands that offer them, and the different forms in which they are available, individuals can make informed decisions about incorporating semaglutide into their weight management journey.

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This video explains how obesity is fundamentally a brain-based condition—shaped by neurohormonal signals like leptin, ghrelin, and GLP-1—not just a matter of willpower or lifestyle. Drawing on neuroscience and psychiatry, Dr Sanil Rege breaks down how dysregulation in homeostatic and hedonic systems can drive weight gain, resistance to weight loss, and why most diets fail. You'll also learn how GLP-1 receptor agonists like semaglutide and tirzepatide target brain circuits to support sustainable weight management. ⏱️ Chapter Breakdown: Timestamps 0:00 – Introduction: Why obesity is more than lifestyle 0:54 – The hypothalamic control centre: AgRP vs POMC neurons 1:07 – Leptin resistance and the broken satiety signal 1:49 – The two systems driving Hunger - Homeostatic and Hedonic 3:02 – GLP-1 receptor agonists: how they work on the brain 3:53 – Psychiatric medications and metabolic disruption 🎓 Educational Highlights: – Obesity is regulated by both homeostatic (hypothalamic) and hedonic (reward) systems in the brain – Leptin resistance and ghrelin signalling contribute to persistent hunger – Diets often fail because of neurobiological adaptations that resist sustained weight loss – GLP-1 receptor agonists target brain centres involved in satiety, cravings, and inflammation – Certain psychiatric medications exacerbate metabolic dysfunction—an integrative approach is key – Practical tools for clinicians include layered pharmacological strategies and patient-centred care 👨‍⚕️ About the Presenter Dr Sanil Rege is a consultant psychiatrist and educator who has trained over 10,000 mental health professionals. Explore advanced psychiatry and neuroscience-based education at The Academy by Psych Scene. #ObesityTreatment #GLP1 #Semaglutide #NeurobiologyOfObesity #WeightLossScience #PsychiatrySimplified #DrRege #PsychSceneAcademy #LeptinResistance #GLP1Agonists #BrainBasedMedicine Related Videos: 👉 What Fasting Does to Your Brain: https://youtu.be/q_5hZUnmsI4 🎓RESOURCES BY PSYCH SCENE: 🌐The Academy by Psych Scene: PSYCHIATRY EDUCATION REDEFINED https://academy.psychscene.com/ Revolutionary psychiatry learning. 🌐Psych Scene Hub: PSYCHIATRY TEXTBOOK OF THE FUTURE https://psychscenehub.com/ The Hub is devoted to making you a better mental health professional. Our team of academic and clinical experts bring you powerful summaries, videos and interviews in psychiatry and neurosciences. 🌐Psych Interview Online: REAL WORLD SKILLS FOR REAL WORLD SUCCESS https://www.psychinterview.com/ The Psych Interview online courses offer high-quality training to help you improve your psychiatric interview skills through self-study. 🌐Psych Scene Online: THE ONLINE COURSES TO HELP YOU SUCCEED https://ranzcpexams.psychscene.com/ Learn at your own pace with the RANZCP Written Exam prep online courses. 🌐Psych Scene: THE PSYCHIATRY TRAINING EXPERTS https://psychscene.com/ Psych Scene offers specialised training and professional development for Psychiatry Trainees, Psychiatrists, General Practitioners and Mental Health Practitioners. -- 📱SOCIALS Subscribe for weekly videos on Psychiatry and Neuroscience: Facebook: https://m.facebook.com/PsychSceneHub Instagram: https://www.instagram.com/psychiatry.excellence/ – 👋 LET’S CONNECT! Follow Sanil Rege on LinkedIn: https://www.linkedin.com/in/sanilrege

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