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Some people follow a ketogenic diet seeking to lose weight, feel more energised, or gain control over their eating habits. Others may turn to this diet in an effort to treat their epilepsy, bipolar disorder, or diabetes. Regardless of their reasoning for adopting this eating pattern, a key question remains: can high LDL cholesterol levels on a ketogenic diet be safe? In Episode #311, I’m joined by Dr William Cromwell, MD and Dave Feldman to explore this question. :point_down: Visit The Proof website for the full show notes and supporting studies. :point_down: https://theproof.com/podcast/ Dr William Cromwell is a lipidologist with over 35 years of clinical practice experience. Since 1990, Dr Cromwell’s practice has specialised in managing lipid and lipoprotein disorders. He has authored over two dozen peer-reviewed papers and book chapters on evaluating and managing lipoprotein disorders and lipoprotein analytics. Dave Feldman is a software and platform engineer, an entrepreneur, and founder of the Citizen Science Foundation. His life took a radical turn on seeing his cholesterol skyrocket after adopting a ketogenic diet, leading him to research lipidology. Through a series of self-experiments and partnering with formal researchers, he has since published the "Lipid Energy Model" which may explain this phenomenon. Connect with Dr William Cromwell: - Twitter/X (personal): /lipoprotein - Twitter/X (Precision Health Reports): / precisehlthrpt - LinkedIn (personal): /wcromwellmd - LinkedIn (Precision Health Reports): / precisionhealthreports - Facebook: / precisionhealthreports - Instagram: / precisehlthrpt - Website (personal): https://www.mylipid.com/ - Website (Precision Health Reports): https://precisionhealthreports.com/ Connect with Dave Feldman: - Twitter/X: / realdavefeldman - YouTube: / @realdavefeldman - Instagram: / realdavefeldman - Citizen Science Foundation: https://citizensciencefoundation.org/ - Own Your Labs: https://ownyourlabs.com/ - Cholesterol Code: https://cholesterolcode.com/ We covered: 00:00 Intro 01:54 Dr. William Cromwell: Background as a Lipidologist and LDL Research 05:34 Dave Feldman's Ketogenic Diet and Elevated LDL Experience 12:30 Unpacking the Lipid Hypothesis and Cardiovascular Risk 20:40 The history and evolution of the lipid hypothesis 23:39 The role of apoB lipoproteins in atherosclerosis 31:59 Factors beyond apoB involved in atherosclerosis and mortality risk 41:43 The complexity of interpreting mortality data in the context of apoB 44:00 Macrophages and the process of atherosclerosis 52:57 Beyond ApoB: Metabolic Vulnerability, Inflammation and Mortality Risk 1:10:35 Transcytosis: A New Perspective on LDL Movement and Atherosclerosis 1:17:33 Exploring Low Cholesterol Impacts and Genetic Disorders 1:22:30 Macrophage Function and Phenotype Across Different ApoB Drivers 1:31:41 Defining Lean Mass Hyper Responders in the Context of a Ketogenic Diet 1:38:00 Investigating PCSK9 and Its Effects on Healthspan 1:44:18 Assessing cardiovascular risk in lean mass hyper-responders 2:02:19 Statin safety, adverse effects, and patient reluctance 2:11:10 Ketogenic Diets and Elevated LDL: Risks and Benefits in the Absence of Long-Term Data 2:18:40 Insulin Resistance, ApoB, and Cardiovascular Risk: Challenges in Assessment and Imaging 2:33:06 Lean Mass Hyper-Responder Study: Design, Recruitment, and Eligibility Criteria 3:05:15 Outro Enjoy, friends. Simon This episode is brought to you by: InsideTracker If you want to improve your health, you need to measure where you’re currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon http://insidetracker.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at http://shopify.com/proof Sun Home Saunas Invest in your body and mind with Sun Home Saunas, pioneers in crafting premium saunas and cold plunges. Safe, effective, research-backed wellness tools to improve cardiovascular health, offer psychological benefits, and reduce muscle soreness. Head to http://sunhomesaunas.com/theproof for $300 off your purchase. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com http://eimele.com/ and use code SIMON at checkout for 10% off your first order. Simon Hill, MSc, BSc (Hons) Creator of http://theproof.com/ and host of The Proof with Simon Hill https://theproof.com/podcast/ Author of The Proof is in the Plants https://theproof.com/book/

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Are you looking for the best keto gummies on the market? Look no further! In this article, we will explore the top-rated keto gummies and what sets them apart from the rest. Whether you are following a ketogenic diet or simply looking for a delicious and convenient way to get your daily dose of vitamins and nutrients, keto gummies are a great option. Keep reading to discover what makes these top-rated keto gummies stand out!

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Keto gummies are a popular choice for those following a ketogenic diet because they are low in carbs and sugar. These gummies are typically sweetened with natural ingredients like stevia or erythritol, making them a healthier alternative to traditional gummy candies. Additionally, many keto gummies are fortified with vitamins and minerals, making them a convenient way to supplement your diet. Some keto gummies also contain collagen, which has been shown to have numerous benefits for skin, hair, and joint health.

One of the main advantages of keto gummies is their convenience. These tasty treats are easy to grab on the go, making them a great option for busy individuals who need a quick and easy snack. Keto gummies are also a fun and delicious way to satisfy your sweet tooth without derailing your diet. With a wide variety of flavors to choose from, you are sure to find a keto gummy that you love.

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When choosing the best keto gummies, there are a few key factors to consider. First and foremost, you want to make sure that the gummies are low in carbs and sugar. Look for gummies that are sweetened with natural ingredients and free from artificial colors and flavors. It’s also important to check the ingredient list for any hidden carbs or sugar alcohols that could affect your ketosis.

In addition to being low in carbs and sugar, top-rated keto gummies should also be high in quality ingredients. Look for gummies that are made with premium ingredients and are free from fillers and additives. Ideally, the gummies should be made with real fruit juice and natural flavors for a delicious and authentic taste. You may also want to choose gummies that are gluten-free, dairy-free, and non-GMO for a cleaner and healthier option.

Another factor to consider when choosing the best keto gummies is the nutritional content. Look for gummies that are fortified with vitamins and minerals, especially those that are common deficiencies on a ketogenic diet. Some keto gummies also contain collagen or other beneficial ingredients for added health benefits. By choosing gummies that are nutritionally dense, you can ensure that you are getting the most out of your snack.

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With so many options available, it can be overwhelming to choose the best keto gummies for your needs. To make the decision easier, consider your personal preferences and dietary restrictions. If you have food allergies or sensitivities, look for gummies that are free from common allergens like gluten, dairy, and soy. You may also want to choose gummies that are vegan or vegetarian if you follow a plant-based diet.

When choosing keto gummies, also consider the flavor options available. Some brands offer a wide variety of flavors to choose from, while others stick to classic options like berry or citrus. You may want to try a few different brands and flavors to find your favorite. Additionally, consider the texture of the gummies – some are chewy and gummy, while others are softer and more gel-like. Choose the texture that you prefer for a satisfying snacking experience.

Finally, consider the price point when choosing keto gummies. While quality ingredients and nutritional content are important, you also want to find gummies that fit within your budget. Compare the cost per serving of different brands to find the best value for your money. Keep in mind that some brands offer discounts for buying in bulk or subscribing for regular deliveries, which can help you save money in the long run.

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In conclusion, top-rated keto gummies are a great option for those following a ketogenic diet or looking for a healthy and convenient snack. These gummies offer a delicious way to satisfy your sweet cravings without derailing your diet. When choosing the best keto gummies for you, consider factors like carb and sugar content, ingredient quality, nutritional content, dietary restrictions, flavor options, texture preferences, and price point. With the right keto gummies, you can enjoy a tasty and nutritious treat that supports your health and wellness goals.

Now that you know what makes top-rated keto gummies stand out, it’s time to find the perfect option for you. Whether you prefer fruity flavors, collagen-infused gummies, or classic chewy textures, there is a keto gummy out there for everyone. Start exploring the world of keto gummies today and discover a delicious and convenient snack that fits seamlessly into your ketogenic lifestyle!

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