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Please Subscribe for 3x Videos Per Week https://www.youtube.com/user/TheTdelauer?sub_confirmation=1 To learn more, visit my website here: http://www.ThomasDeLauer.com Get the Apparel I Wear at http://www.Hylete.com Weight Loss | How Fat Burning Works | Lipolysis Explained– Thomas DeLauer… So you want to burn fat - what exactly does that mean? In order to burn fat most efficiently, it is important to first understand how fat metabolism works. Fat must be released from our cells. Only once the fat has been released can it be burned and used for energy. The majority of fat in our bodies resides in fat cells. These cells are made up of roughly 15% lean mass and 85% fat, in the form of a lipid droplet. To use this fat we must get it to cross over the cell membrane of the fat cell. This process is called lipolysis. An enzyme called hormone-sensitive lipase takes a triglyceride, the fat in the cell, and separates the three fatty acids from the glycerol. This frees the fatty acids to pass through the cell membrane to be made available to the Krebs Cycle. So to use your stored fats as fuel, you need to produce hormone-sensitive lipase. Many hormones are involved here, but the one that you want to be most concerned with is insulin. If you have high levels of insulin in your blood, you are going to have low levels of lipase. Dietary carbohydrates are the main contributor to your blood insulin levels. So how do we burn our stored fat? The Krebs Cycle: You may remember from biology class the Citric Acid Cycle, also known as the Krebs cycle. Mitochondria are found in the hundreds to thousands in all cells in our body (except mature red blood cells). Here, energy from what we eat, the carbohydrates, fats and proteins, are converted into ATP. Acetyl COA is used to form the energy, or ATP, in the Krebs cycle: If you are consuming carbohydrates or eating too frequently, your blood is going to have high insulin levels and there will be carbohydrates that you have recently eaten available as the fuel for the Krebs Cycle. Traditionally, carbohydrates that you eat are broken down in your body. The glucose undergoes a process called glycolysis and pyruvate is formed. In the mitochondrial matrix, pyruvate undergoes oxidation and ACOA is formed. ACOA can also be formed from the breakdown of fats and amino acids, or the building blocks of proteins. How your body uses its energy is dependent upon what you eat. Traditionally, when you are in a normal state, your body is using carbohydrates for their main energy source through the citric acid cycle. If you change how you eat, you can train your body to instead form ACOA through the breakdown of ketone bodies. How Does it Work? When glucose is in short supply, your body begins lipolysis. These free fatty acids, rather than carbohydrates from your food, are used to produce ACOA. Once the fatty acids have been released into your bloodstream, they bind to a protein called albumin. Albumin shuttles the fatty acids to the muscle cells where they are taken into the mitochondria as ACOA. In very fit athletes the muscle cells themselves will begin to store the lipid droplets in them rather than glucose for immediate energy fuel. Lipogenesis: When you eat carbohydrates, they break down into glucose in your blood. The pancreas secretes insulin to shuttle the glucose out of the blood and into either the muscle or liver for immediate use, glycogen storage, or they be stored as fat. Your liver and muscle cells have a limited capacity for glycogen storage that is not very high. This means that when you consume excess carbs your body has to store them as fat through a process called lipogenesis. Simply put, lipogenesis is the creation of fatty acids from carbohydrates that you consume. While for our ancestors in the hunting and gathering days this storage of energy was great, in the age of abundance we are struggling with the health impacts of storing excess fat. This fat storage follows a process very similar to the Krebs Cycle discussed. Once the ACOA is created, if the body does not need to use it for energy or for storage in the muscles and liver, it is stored through lipogenesis as fat for later use. References: 1. The Citric Acid Cycle https://www.khanacademy.org/science/biology/cellular-respiration-and-fermentation/pyruvate-oxidation-and-the-citric-acid-cycle/a/the-citric-acid-cycle 2. The citric acid cycle oxidized two-carbon units http://www.ncbi.nlm.nih.gov/books/NBK22427/ 3. What is Ketosis? Our article :) 4. Fat Breakdown and Fat Burning: Lipolysis and Oxidation http://leanmessengers.com/fat-breakdown-and-fat-burning-lipolysis-and-oxidation/ 5. How and what am I digesting? A breakdown of macronutrient… http://leanmessengers.com/?s=lipogenesis 6. Lipid catabolism summary http://chemistry.elmhurst.edu/vchembook/622overview.html 7. Acetyl COA - Crossroads Compound http://chemistry.elmhurst.edu/vchembook/623acetylCoAfate.html
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Semaglutide has been making waves in the weight loss community as an effective treatment for obesity. Originally developed as a diabetes medication, semaglutide has shown promising results in helping individuals shed excess pounds. If you’re considering using semaglutide for weight loss, it’s important to understand how to start and what to expect. In this article, we’ll explore the process of getting semaglutide for weight loss and provide helpful tips for incorporating it into your weight loss journey.
Consult with a Healthcare Provider
The first step in starting semaglutide for weight loss is to consult with a healthcare provider. Your doctor will evaluate your medical history, current medications, and overall health to determine if semaglutide is a safe and appropriate option for you. It’s important to be honest and open with your healthcare provider about your weight loss goals and any concerns you may have.
Your doctor may also recommend lifestyle changes such as diet and exercise to complement the use of semaglutide. A comprehensive approach that includes both medication and lifestyle modifications is often the most effective way to achieve long-term weight loss success.
During your consultation, be sure to ask any questions you have about semaglutide, including how it works, potential side effects, and expected results. Your healthcare provider can provide personalized guidance to help you make an informed decision about incorporating semaglutide into your weight loss plan.
Obtain a Prescription
Once you and your healthcare provider have decided that semaglutide is an appropriate option for you, the next step is to obtain a prescription. Semaglutide is available in various formulations, including injectable pens and tablets. Your doctor will prescribe the specific formulation and dosage that is most suitable for your needs.
It’s important to follow your doctor’s instructions carefully when using semaglutide. This may include taking the medication at a certain time each day, following a specific dosing schedule, and monitoring your progress regularly. Your doctor may also recommend regular check-ups to ensure that semaglutide is working effectively and safely for you.
Be sure to discuss any concerns or difficulties you have with using semaglutide with your healthcare provider. They can provide guidance and support to help you navigate the process of incorporating semaglutide into your weight loss regimen.
Start Treatment
Once you have obtained your prescription for semaglutide, it’s time to start treatment. Follow your doctor’s instructions carefully regarding when and how to take the medication. Semaglutide works by mimicking the effects of a hormone called GLP-1, which helps regulate blood sugar levels and appetite.
In addition to taking semaglutide as prescribed, it’s important to continue making healthy lifestyle choices to support your weight loss goals. This may include eating a balanced diet, staying active, getting enough sleep, and managing stress. Semaglutide is most effective when used in conjunction with healthy habits that promote overall well-being.
Keep track of your progress while using semaglutide, including any changes in weight, appetite, energy levels, and other relevant factors. Your doctor may recommend regular follow-up appointments to monitor your response to the medication and make any necessary adjustments to your treatment plan.
Stay Committed
As you continue your journey with semaglutide for weight loss, it’s important to stay committed to your goals and maintain a positive attitude. Weight loss is a gradual process that requires patience, persistence, and perseverance. Remember that everyone’s experience with semaglutide may be different, so it’s essential to focus on your own progress and celebrate small victories along the way.
Set realistic and achievable goals for yourself, whether it’s losing a certain amount of weight, improving your eating habits, or increasing your physical activity. Keep a journal or diary to track your daily progress, challenges, and successes. Having a support system in place, whether it’s friends, family, or a healthcare provider, can also help keep you motivated and accountable on your weight loss journey.
If you experience any difficulties or setbacks while using semaglutide, don’t hesitate to reach out to your healthcare provider for guidance and support. They can help troubleshoot any issues you may be facing and provide strategies to help you stay on track with your weight loss goals.
In conclusion, incorporating semaglutide into your weight loss plan can be a valuable tool in helping you achieve your desired outcomes. By consulting with a healthcare provider, obtaining a prescription, starting treatment, and staying committed to your goals, you can maximize the benefits of semaglutide for weight loss. Remember that weight loss is a journey that requires dedication and perseverance, but with the right support and guidance, you can achieve long-lasting success.
Summary and FAQ
Overall, semaglutide can be a helpful tool in managing weight loss, especially for individuals struggling with obesity or related health conditions. By following the necessary steps to obtain and use semaglutide safely and effectively, you can enhance your weight loss efforts and improve your overall well-being.
Here are some frequently asked questions about using semaglutide for weight loss:
1. How does semaglutide work to promote weight loss?
2. What are the potential side effects of using semaglutide?
3. How long does it take to see results with semaglutide?
4. Can I stop taking semaglutide once I reach my weight loss goals?
5. Will using semaglutide for weight loss interact with other medications I am taking?
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Click here to kickstart your fat loss journey with a customized fitness plan— try it free for 2 weeks: https://bws.plus/_a Tons of fitness videos promise the secret to fast fat loss... Then hit you with a “fat loss workout” that’d make a Navy SEAL throw up, a “fat loss diet” that repeatedly calls for boiled chicken for lunch… and lots of crying. If you’re not suffering, it’s not working. But what if I told you a simple walking method can help you lose fat faster than killing yourself with cardio? I know that sounds hard to believe, but it’s just one of four science-backed fat loss strategies I’ll show you to help you lose fat up to 2x faster—without losing muscle. And I’ve crunched the numbers to prove it. 0:00 - 0:30 : Why Most Fat Loss Plans Fail 0:30 - 4:04 : Adjusting Fat Intake 4:05 - 7:30 : The Walking Method 7:31 - 11:06 : The Accidental Deficit 11:07 - 13:37 : Unique Foods For Fat Loss 13:38 : What Results To Expect The first fat loss strategy is adjusting your fat intake. For health reasons you don’t want to go below around 35 to 50 grams of fat per day. Here's what I want you to do: Think about the fats you eat everyday. Cheese, butter, and even healthy fats like avocado. Starting tomorrow, cut however much you usually have of these in half. I want you to also check if you’re eating any high fat proteins. Try having just one of these daily, then for all your other meals, choose a more pure protein source from this list. And you can apply this same concept even when you’re eating out. If you just cut 1 fat source in half and make 1 protein swap, boom you’re saving up to 250 calories per day, which already speeds up your fat loss by half a pound per week. And you can lose even more by combining it with the next strategy, the walking method. What most people don’t know is that instead of relying on a specific “fat loss workout”, a highly active person can burn up to 2,000 more calories daily just from NEAT compared to someone who's sedentary. While cardio is great for your heart and health, it’s kind of just “meh” for fat loss. A much better approach I personally use myself and with our Built With Science clients is plain old walking. Now I’ve set a goal in my Built With Science app to hit 10,000 steps a day and it keeps track of it for me. But you can use the health app on your phone, and just aim for anywhere between 7,000 to 12,000 steps a day. But 30 minutes of walking is already 3,000 steps and for the average person can burn anywhere from 100 to 200 calories. Do that simple 30 minute walk every day and after a month you’ll lose an extra pound of fat, or an extra quarter pound of fat per week. And you can speed this up even faster with a dieting strategy I call the accidental deficit. During your busiest days, rely on quick grab-and-go protein sources and ready to eat fruits. Then when you finally get home, have a big dinner of lean protein and vegetables instead of ordering takeout. Then, just go to bed before you start snacking. If you do this right, you could end your day eating as little as 1,300 to 1,600 calories. For most people this is a huge deficit and is why I do NOT recommend doing this “fat loss diet” more than once or twice a week max - and preferably on your rest days. But even just doing this once a week can increase your average daily calorie deficit by about 100 calories, and help you get rid of an extra quarter pound per week. But this will work even better if you combine it with the last strategy for fast fat loss - eating foods that do the work for you. Most people don’t know this but your body burns a certain amount of calories just from digesting food. And protein is special because a solid 20 to 30% of its calories immediately get burned up for digestion, absorption, and metabolism - which is more than double any other food. As a result, studies have shown going from a low-protein to a high-protein diet can raise your daily calorie burn by 4–5%. For a 2000 calorie diet, that’s an extra 90–100 calories burned per day. It may not sound like much, but that’s like doing a 10 minute jog everyday, and can add up to a pound of fat loss every month. Not to mention all the muscle building benefits this has as well. So take your bodyweight in lbs and multiply it by 0.8. If you’re not getting anywhere near that, then bump up how much protein you have in each meal to get closer to that target. And if you’re already hitting that, great, focus on swapping your processed foods for whole foods high in fiber and resistant starch. Put all 4 strategies together, and even being conservative with the numbers, you're looking at an extra 1.2 pounds of fat loss per week. That’s over twice what most people manage on a typical diet.
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