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GLP-1 receptor agonists like semaglutide and tirzepatide are transforming the fields of regenerative medicine, longevity, and performance health—but they’re not just for weight loss. In this episode of the Rare Wellness Podcast, Dr. Jamie Lewis breaks down how these powerful peptides work, their surprising benefits beyond metabolic health, and their role in reducing inflammation, enhancing cognitive function, supporting pain management, and even improving recovery and healing. 🔹 How GLP-1 RAs work to regulate blood sugar & metabolism 🔹 The unexpected benefits for cognitive health & neuroprotection 🔹 How these medications help with pain relief & inflammation 🔹 Why GLP-1s are a game changer for longevity & vitality If you're curious about these cutting-edge treatments and how they can optimize your health, this episode is for you! 💡 Learn more about Dr. Jamie Lewis & book a consultation at: www.nwc4rm.com and www.rarewellness.com 👍 If you found this episode valuable, please like, subscribe, and share to support our mission of making wellness accessible to all. Works Cited: Wilding, J. P., et al. (2021). "Once-Weekly Semaglutide in Adults with Overweight or Obesity." The New England Journal of Medicine. Jastreboff, A. M., et al. (2022). "Tirzepatide Once Weekly for the Treatment of Obesity." The New England Journal of Medicine. Davies, M., et al. (2022). "Semaglutide 2.4 mg in Adults with Obesity or Overweight: Effects on Weight Loss and Maintenance." The Lancet. Wadden, T. A., et al. (2022). "Weight Regain After Discontinuation of GLP-1 Receptor Agonists." Obesity Reviews. Drucker, D. J. (2018). "Mechanisms of Action and Therapeutic Applications of GLP-1 Agonists in Inflammation and Neuroprotection." Cell Metabolism. Holst, J. J., et al. (2020). "GLP-1 and its Role in Modulating Immune Function and Inflammation." Diabetes Care. Ashina, M., et al. (2021). "GLP-1 Agonists in the Modulation of Pain Hypersensitivity: Implications for Migraine Management." The Journal of Headache and Pain. Healthline. (2022). "Ozempic for Severe Osteoarthritis Knee Pain." Retrieved from healthline.com. "Glucagon-like peptide-1: a multi-faceted anti-inflammatory agent." Frontiers in Immunology, 2023. Retrieved from frontiersin.org. "Beyond Glycemic Control: Exploring GLP-1 Agonists for Diabetic Foot Ulcer Healing." Diabetic Foot Online, 2024. Retrieved from diabeticfootonline.com. "GLP-1 drugs linked to fewer post-surgical complications in diabetic patients." News-Medical, 2025. Retrieved from news-medical.net
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In this video Doctor O'Donovan explains key facts you need to know about a medication called METFORMIN used to treat type 2 diabetes (also known as Glucophage, Fortamet, Axpinet, Diagemet, Glucient, Metabet). In the video we cover: What is metformin? (0.36) Who can and can't take it? (1.34) How to take it (2.36) Side effects (4.49) Use in pregnancy (7.40) Interactions (8.15) Key facts - Not everyone gets diabetes symptoms, so taking metformin may not make you feel any different. That does not mean it is not working, so keep on taking it. - It's best to take metformin with a meal to reduce the side effects. The most common side effects are feeling and being sick, diarrhoea, stomach ache and loss of appetite. Vitamin B12 deficiency is also a common side effect of taking metformin in higher doses or for long periods. - Metformin does not cause weight gain, unlike some other diabetes medicines. - If you have diabetes, you can get free prescriptions for all of your medicines, not just your diabetes ones. You'll need to have a medical exemption certificate. Further information via NHS website: https://www.nhs.uk/medicines/metformin/ Patient information leaflet: https://www.medicines.org.uk/emc/product/594/pil #doctor #diabetes #medication #pharmacy ************************************************************************ Connect through: YouTube: www.youtube.com/doctorodonovan TikTok: @doctorodonovan ************************************************************************** Disclaimer: The video is intended as an educational resource only. The information within this video or on this channel isn't designed to replace professional input, so if you have any medical issues please consult a medical provider. No professional relationship is being created by watching this video. Dr. O’Donovan cannot give any individual medical advice. All information should be verified for accuracy by the individual user. Dr O’Donovan accepts no responsibility for individual interpretation of data, although it is always accurate to the best of his knowledge at the time of the video being published. This is an EDUCATIONAL video. Images are used in accordance with fair use guidelines. Legal information: Content provided via YouTube is for general information purposes ONLY. Information videos are not produced to provide individualised medical advice. Medical education videos on Doctor O'Donovan are not a substitute for professional professional medical advice, diagnosis or treatment. NEVER ignore professional medical advice because of something you have heard here. ALWAYS consult your doctor regarding any concerns about your condition or treatment.

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