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One of the most exciting developments in weight loss medications in recent years has been the approval of semaglutide for this purpose. Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that was originally developed for the treatment of type 2 diabetes. However, studies have shown that it can also be highly effective for weight loss in individuals with obesity or overweight. There are different formulations of semaglutide available for weight loss, each with its own brand name and dosing regimen.
Which Semaglutide Is Approved for Weight Loss?
The semaglutide formulation that is approved specifically for weight loss is called Wegovy. Wegovy is a higher dose of semaglutide compared to the dose used for the treatment of diabetes. It is administered as a subcutaneous injection once a week and is typically used in conjunction with a reduced-calorie diet and increased physical activity. Wegovy works by acting on the brain to reduce appetite and increase feelings of fullness, which can help people lose weight over time.
Another semaglutide formulation that is used for weight loss is called Ozempic. Ozempic is approved for the treatment of type 2 diabetes but has also been shown to promote weight loss in some people. It is administered as a subcutaneous injection once a week and works in a similar way to Wegovy to help control appetite and promote weight loss. While not specifically approved for weight loss, some healthcare providers may prescribe Ozempic off-label for this purpose.
It’s important to note that semaglutide for weight loss is intended for individuals who have a body mass index (BMI) of 30 or higher, or a BMI of 27 or higher with at least one weight-related comorbidity, such as high blood pressure or type 2 diabetes. Before starting treatment with semaglutide, it’s essential to consult with a healthcare provider to determine if it is a suitable option and to discuss potential risks and benefits.
Approved Brands
As mentioned earlier, Wegovy is the brand name for the semaglutide formulation approved specifically for weight loss. It is available in a pre-filled pen that allows for easy self-administration at home. Ozempic, on the other hand, is the brand name for the semaglutide formulation approved for the treatment of type 2 diabetes, but it may also have weight loss benefits for some individuals.
Other brand names for semaglutide include Rybelsus, which is a tablet formulation of semaglutide used for the treatment of type 2 diabetes. While Rybelsus is not specifically indicated for weight loss, some studies have shown that it can help with weight management in people with diabetes. Like Ozempic, Rybelsus may be prescribed off-label for weight loss in some cases.
Overall, semaglutide is a promising option for individuals struggling with obesity or overweight who have not been able to achieve significant weight loss with diet and exercise alone. By working to reduce appetite and increase feelings of fullness, semaglutide can help support healthy weight loss when used as part of a comprehensive weight management plan.
For more information about semaglutide for weight loss and to see if it may be a suitable option for you, be sure to speak with your healthcare provider.
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Weight loss medications Ozempic and Wegovy, in particular, have been scrutinized for their high out-of-pocket costs.

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