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This video explains how obesity is fundamentally a brain-based condition—shaped by neurohormonal signals like leptin, ghrelin, and GLP-1—not just a matter of willpower or lifestyle. Drawing on neuroscience and psychiatry, Dr Sanil Rege breaks down how dysregulation in homeostatic and hedonic systems can drive weight gain, resistance to weight loss, and why most diets fail. You'll also learn how GLP-1 receptor agonists like semaglutide and tirzepatide target brain circuits to support sustainable weight management. ⏱️ Chapter Breakdown: Timestamps 0:00 – Introduction: Why obesity is more than lifestyle 0:54 – The hypothalamic control centre: AgRP vs POMC neurons 1:07 – Leptin resistance and the broken satiety signal 1:49 – The two systems driving Hunger - Homeostatic and Hedonic 3:02 – GLP-1 receptor agonists: how they work on the brain 3:53 – Psychiatric medications and metabolic disruption 🎓 Educational Highlights: – Obesity is regulated by both homeostatic (hypothalamic) and hedonic (reward) systems in the brain – Leptin resistance and ghrelin signalling contribute to persistent hunger – Diets often fail because of neurobiological adaptations that resist sustained weight loss – GLP-1 receptor agonists target brain centres involved in satiety, cravings, and inflammation – Certain psychiatric medications exacerbate metabolic dysfunction—an integrative approach is key – Practical tools for clinicians include layered pharmacological strategies and patient-centred care 👨‍⚕️ About the Presenter Dr Sanil Rege is a consultant psychiatrist and educator who has trained over 10,000 mental health professionals. Explore advanced psychiatry and neuroscience-based education at The Academy by Psych Scene. #ObesityTreatment #GLP1 #Semaglutide #NeurobiologyOfObesity #WeightLossScience #PsychiatrySimplified #DrRege #PsychSceneAcademy #LeptinResistance #GLP1Agonists #BrainBasedMedicine Related Videos: 👉 What Fasting Does to Your Brain: https://youtu.be/q_5hZUnmsI4 🎓RESOURCES BY PSYCH SCENE: 🌐The Academy by Psych Scene: PSYCHIATRY EDUCATION REDEFINED https://academy.psychscene.com/ Revolutionary psychiatry learning. 🌐Psych Scene Hub: PSYCHIATRY TEXTBOOK OF THE FUTURE https://psychscenehub.com/ The Hub is devoted to making you a better mental health professional. Our team of academic and clinical experts bring you powerful summaries, videos and interviews in psychiatry and neurosciences. 🌐Psych Interview Online: REAL WORLD SKILLS FOR REAL WORLD SUCCESS https://www.psychinterview.com/ The Psych Interview online courses offer high-quality training to help you improve your psychiatric interview skills through self-study. 🌐Psych Scene Online: THE ONLINE COURSES TO HELP YOU SUCCEED https://ranzcpexams.psychscene.com/ Learn at your own pace with the RANZCP Written Exam prep online courses. 🌐Psych Scene: THE PSYCHIATRY TRAINING EXPERTS https://psychscene.com/ Psych Scene offers specialised training and professional development for Psychiatry Trainees, Psychiatrists, General Practitioners and Mental Health Practitioners. -- 📱SOCIALS Subscribe for weekly videos on Psychiatry and Neuroscience: Facebook: https://m.facebook.com/PsychSceneHub Instagram: https://www.instagram.com/psychiatry.excellence/ – 👋 LET’S CONNECT! Follow Sanil Rege on LinkedIn: https://www.linkedin.com/in/sanilrege

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Stdei GLP-1 Review: Is STDEI GLP-1 Weight Loss Oral Solution Legit Or Scam? In this Video, we dig deep into the red flags surrounding STDEI GLP-1 — from fake endorsements and unrealistic weight-loss claims to a complete lack of scientific proof. While the product promises metabolism boosting, fat burning, and FDA approval, there’s a lot that doesn’t add up. We’ll explore why this supplement is not available on trusted platforms like Amazon or Walmart, how it mimics other shady products like Piguiay GLP-1 Drops, and why its fake reviews and copied medical endorsements should raise serious concerns. If you’re considering buying STDEI GLP-1, this video could save you from wasting money or risking your health. 👉 Watch till the end to get the full picture and protect yourself from misleading marketing! Tags: STDEI GLP-1 review, STDEI weight loss scam, GLP-1 drops scam, weight loss supplement scam, STDEI oral solution review, meglutide weight loss supplement reviews, Piguiay GLP-1 alternative, STDEI GLP-1 reviews ,STDEI GLP-1 reviews reddit,STDEI GLP-1 review trustpilot #STDEIGLP1 #WeightLossReview #SupplementScam #GLP1Review Copyright Disclaimer: - Under section 107 of the Copyright Act 1976, allowance is made for FAIR USE for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is permitted by copyright statutes that might otherwise be infringing. Non-profit, educational, or personal use tips the balance favor of FAIR USE.

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In this insightful video, Mike Israetel, the founder of Renaissance Periodization, delves into the misconception surrounding massive calorie restrictions for weight loss. With his extensive expertise in nutrition and training, Israetel explains why extreme calorie cuts are not only unsustainable but also counterproductive in the long run.Wie Kann Man Wirklich Schnell Abnehmen Ein Detaillierter Plan

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Merimed Keto Extreme Advanced Weight Management Tablet is a dietary supplement that claims to aid in weight loss. –––––––––––––––––––––––––––––– #UseInHindi #Use #Hindi –––––––––––––––––––––––––––––– Topics Covered keto extreme advanced weight management tablet uses keto extreme advanced weight management tablet review weight management tablet weight loss tablets without side effects weight loss tablets in hindi weight loss tablets for women –––––––––––––––––––––––––––––– Disclaimer: We are not promoting any medicine in our videos, our videos are for educating people about all medicines. Also, we are not suggesting anyone to take any medicine without the suggestion of your doctor. So this video is for information purposes only, always ask your doctor before eating any medicine. –––––––––––––––––––––––––––––– SOME IMAGES ARE USED AS ILLUSTRATIONS FOR EDUCATIONAL PURPOSE UNDER FAIR USE - All images and videos used are in Public Domain –––––––––––––––––––––––––––––– Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for 'fair use' for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use.

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Running and weigh-in, plus me talking about stuff... and new protein powder! DAD UPDATE: He's home from the hospital and doing OK. Speech is still a little slurry, and he's lost like 15 lbs so he's pretty underweight, but my step-mom is taking care of him and he seemed in good spirits when he called. I can't wait to see him in April - I haven't seen him since Dec 2006. WEIGHT: It's a loss. For Jess' challenge I've lost a total of 9.6 lbs so far. AND I THOUGHT I COULDN'T LOSE 5 BY MAY *headdesk* Thanks for pushing me to believe in my losing power, Jess! :D

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