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Myocardial infarction (MI), commonly known as a heart attack, is a serious medical condition that always requires comprehensive and targeted care to facilitate optimal recovery. In recent years, medical science has made significant strides in the development of innovative therapies, including peptide therapy Among these, GLP-1 agonists (glucagon-like peptide-1 agonists) have emerged as a promising avenue for post-MI care. In this podcast, we’ll talk about the important role of GLP-1 agonists in the context of post-MI management and how these peptides are revolutionizing cardiovascular treatment strategies. What are GLP-1 Agonists? GLP-1 agonists are a class of medications initially designed to manage type 2 diabetes. They mimic the action of glucagon-like peptide-1, a natural hormone that regulates blood sugar levels. In recent years, researchers have discovered that these agonists offer benefits that extend beyond glycemic control. They have been shown to suppress appetite aiding in significant weight loss and have shown remarkable cardioprotective properties, making them valuable therapeutic options, especially in the post-MI period. What are the cardioprotective effects of GLP-1 Agonist? Improving Cardiac Function: GLP-1 agonists have been found to enhance cardiac function by improving the heart's pumping ability and reducing the workload on the cardiovascular system. This effect is particularly helpful after a heart attack when the heart muscle needs support to recover and function efficiently. It is also helpful for those who have heart failure. Reducing Inflammation: Inflammation plays a big role in the progression of heart damage after a heart attack. GLP-1 agonists have anti-inflammatory properties, reducing inflammation within the cardiovascular system. By mitigating inflammation, these medications aid in preventing further damage to the heart tissue, helping the healing process. Promoting Vasodilation: GLP-1 agonists promote vasodilation, which means they relax blood vessels, reducing blood pressure and improving blood flow. This effect is vital post-heart attack as it helps reduce the strain on the heart and prevents complications related to high blood pressure. Mitigating Oxidative Stress: Oxidative stress is caused by an imbalance between free radicals and antioxidants in the body. This can exacerbate heart damage post-heart attack. GLP-1 agonists have antioxidant properties, helping prevent ischemia and reperfusion injury. This is important for many reasons. Ischemia occurs when the blood supply to a specific part of the body is reduced or completely blocked, leading to oxygen and nutrient deprivation. Reperfusion injury, on the other hand, happens when the blood supply is restored after a period of ischemia. Surprisingly, the reintroduction of oxygen-rich blood can exacerbate tissue damage due to the production of free radicals and inflammatory responses, leading to further cellular injury and dysfunction. Anti-atherosclerotic: Atherosclerosis is a condition where these plaques build up, narrowing the arteries and restricting blood flow. This narrowing can lead to various cardiovascular problems, including heart attacks and strokes. GLP-1 agonists help reduce the overall amount of plaque on the inner walls of the heart's arteries, decreasing the risk of heart attack or stroke. Individualizing Treatment in Post-MI Care: It's important to note that the use of GLP-1 agonists in post-MI care should be individualized. Healthcare providers carefully assess patients' overall health, existing conditions, and medical history to determine the safety of these medications. And remember, while GLP-1 agonists offer significant benefits, they are just one component of a comprehensive post-MI treatment plan. Lifestyle modifications, such as a heart-healthy diet, regular exercise, and smoking cessation, are equally vital in ensuring a holistic approach to recovery. When you have a heart attack, you’ll need immediate emergency medical care and procedures to help stabilize and save your heart. Typical medications used in the hospital are oxygen, pain relievers like nitroglycerin and morphine, blood thinners like heparin to stop clots from forming, beta-blockers like metoprolol to help reduce how hard your heart is working, cholesterol medications like Lipitor (statin) to help prevent further plaque build-up and ACE-inhibitors like lisinopril to help lower your blood pressure. Once your heart attack has passed, you’ll likely need long-term medications to help prevent you from having another heart attack. These include medications like blood thinners, blood pressure medications, beta-blockers, and cholesterol medications. In some cases, your healthcare provider might prescribe a GLP-1 agonist like semaglutide or liraglutide. If you’ve been prescribed semaglutide or liraglutide, you’ll start at a low dose to help your body...

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Unlock the future of weight loss medication! Look beyond semaglutide and tirzepatide, and uncover the science behind groundbreaking weight loss drugs and strategies. #ozempic #mounjaro For more information about this topic: https://brianyeungnd.com/2024/01/04/new-obesity-drugs-in-2024/ Get EXCLUSIVE content and SUPPORT us: https://ko-fi.com/brianyeungnd 0:00 Intro 0:37 Current GLP-1 Agonists 1:41 New and Improved GLP-1 Agonists 5:06 New Brands of Semaglutide 5:50 Targeting New Receptors 7:25 New Mechanisms of Action **************** Learn more about: Wegovy vs Mounjaro: https://youtu.be/Nsh3tE4WmJw Orforglipron vs Semaglutide vs Danuglipron: https://youtu.be/sR2pxGNvEQ0 GLP-1 Agonists for Weight Loss: https://youtu.be/U52FTYIQolY Dr. Brian Yeung, ND: https://brianyeungnd.com/about/ **************** DISCLAIMERS Affiliate links: Please keep in mind that we may receive a commission when you click on our links and make a purchase. This, however, has no bearing on our reviews and comparisons. Content: All statements made are opinions and not stated as fact. While Dr. Brian and his team makes every effort to fact check the information presented, mistakes can still be made. Dr. Brian and his team are not responsible for any errors or omissions in the information provided. The intent of this channel is not to malign or harm the reputation of any individual, company, or organization. All criticisms are made in good faith and with the aim of providing constructive feedback. Copyright: All content, including but not limited to videos, designs, and captions, produced by Dr. Brian is protected under copyright law. Any unauthorized reproduction, distribution, or display of our content, in part or in whole, is strictly prohibited. We do not give permission for anyone to translate and/or reupload our videos, designs, or captions on YouTube or other social media platforms. Any such activity will be considered a violation of our intellectual property rights and may result in legal action. Medical: Dr. Brian Yeung, ND received his Doctor of Naturopathic Medicine degree from the Canadian College of Naturopathic Medicine in 2013. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Yeung is currently a practicing Naturopathic Doctor with additional prescribing authority and IV therapy certification in Ontario. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Yeung and you. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. BrianYeungND and Dr. Brian Yeung, ND are not liable or responsible for any advice, course of treatment, diagnosis or any conclusions drawn, services or product you obtain through this video or site.

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