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Lizzo has revealed that she briefly used Ozempic as part of her weight loss journey. In a candid conversation on Thursday's episode of Trisha Paytas' Just Trish podcast, the 37-year-old singer opened up about her decision to try the GLP-1 medication at the start of her transformation in 2023. However, she quickly realized that Ozempic wasn't the long-term solution she was looking for.

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This week, Dave covers massive GLP-1 news out of Connecticut, a new GLP-1 heart study that changes the conversation, and a big OTP event opportunity announcement!

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Check out My FREE Healthy Keto Acceptable Foods List 👉 https://drbrg.co/49VqRV3 These are some of the healthiest foods to eat. Are you including them in your diet? Vitamin U: https://en.wikipedia.org/wiki/S-Methylmethionine Cod Liver ICan: https://ican.is/products/ Red Meat Causing Cancer, Heart Disease, Stroke, and Diabetes? ▶️ https://youtu.be/ykcMGi4vM-w ▶️ https://youtu.be/GmHnFk4uVuQ More Videos on Extra Virgin Olive Oil: ▶️ https://youtu.be/fV8tCONOf6k ▶️ https://youtu.be/7TwBxHZDAhg ▶️ https://youtu.be/5Y-i1dGqAOc DATA: https://pubmed.ncbi.nlm.nih.gov/16136122/ https://pubmed.ncbi.nlm.nih.gov/21443487/ https://pubmed.ncbi.nlm.nih.gov/29149823/ 0:00 Introduction 0:10 Foods that can make you sick 0:33 What is the healthiest diet? 1:32 The 7 healthiest foods The top healthiest foods: 1. Sauerkraut 1 cup = 1.9g net carbs Top benefits of sauerkraut: • It's high in vitamin C • It's a good prebiotic and probiotic • It's high in powerful phytonutrients • It's easy to digest • It's high in lactic acid • It's high in vitamin K2 • It's high in vitamin U 2. Arugula 1 cup = .43g net carbs Top benefits of arugula: • It's high in powerful phytonutrients • It supports liver function • It's low in oxalates • It's anti-inflammatory • It's high in nitric oxide • It's high in calcium, potassium, folate, magnesium, vitamin C, and vitamin K1 • It's anti-cancer 3. Salmon (wild-caught, fatty, and skin-on) Fat to protein ratio: 1:2 Top benefits of salmon: • It's high in selenium • It's high in omega-3 fatty acids • It's high in vitamin K2, zinc, and calcium 4. Cod liver (wild-caught) Fat to protein ratio: 5:1 Top benefits of cod liver: • It's high in omega-3 fatty acids • It's high in vitamin A, vitamin D, vitamin K2, iodine, and B vitamins 5. Hamburger (grass-fed, fatty, and organic) Fat to protein ratio: 2:1 Top benefits of hamburger: • It's easy to digest • It's low on the insulin index • It's a good source of amino acids • It's a good source of available iron • It's high in phosphorus, selenium, zinc, B12, B5, B3, B2, and B6 • It's high in carnosine • It's high in creatine 6. Pecans 1 cup = 4g net carbs Fat to protein ratio: 7:1 Top benefits of pecans: • They're low on the insulin index • They're high in zinc and copper • They're high in vitamin B1 • They're low in oxalates • They're high in antioxidants • They're easy to digest 7. Extra virgin olive oil Top benefits of extra virgin olive oil: • It contains vitamin E and vitamin A • It contains magnesium and potassium • It has zero effect on insulin • It contains powerful phytonutrients • It supports anti-aging • It supports and repairs mitochondria (it's anti-cancer) • It's anti-inflammatory and may help relieve pain • Compounds in extra-virgin olive oil may help reduce beta-amyloids • It's anti-clotting • It's antimicrobial • It's retinal protective Dr. Eric Berg DC Bio: Dr. Berg, age 57, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media. Follow Me On Social Media: Facebook: https://bit.ly/FB-DrBerg Instagram: https://bit.ly/IG-DrBerg TikTok: https://bit.ly/TikTok-DrBerg Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients so he can focus on educating people as a full time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. #keto #ketodiet #weightloss #ketolifestyle

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These drugs--Tirzepatide and Semaglutide--are not just changing the weight loss game. Every day new information is published regarding their efficacy in a wide range of chronic illnesses. They give us an exciting new tool for the management of complex illness. - The topic is GLP-1 receptor agonists (GLP-1 RAs), such as Ozempic, Wegovy, and Mounjaro (semaglutide and tirzepatide). - These drugs, originally developed for diabetes and weight loss, are being explored for broader benefits in patients with complex chronic illnesses, including long COVID and mast cell activation syndrome (MCAS). ### **Clinical Observations** - The hosts recount remarkable improvements in patients with severe, treatment-resistant symptoms (e.g., long COVID, MCAS) after starting very low doses of GLP-1 RAs. - Examples include: - A physician with disabling long COVID who, after starting a low dose of tirzepatide, regained mobility and improved overall function. - A woman with post-COVID and post-vaccine reaction, severe edema, food intolerance, and autoimmune markers, who experienced a dramatic reduction in swelling and improved food tolerance after just three injections. ### **Mechanisms & Theoretical Discussion** - GLP-1 is a natural hormone involved in insulin secretion and glucose metabolism; synthetic versions are longer-acting. - GLP-1 receptors are found throughout the body: central nervous system, muscles, immune cells (including mast cells), joints, and more. - The hosts hypothesize that the drugs’ benefits in complex illness may stem from: - Mast cell stabilization (reducing multi-system inflammation). - Modulation of immune function. - Effects on the central nervous system, possibly crossing the blood-brain barrier. - Notably, benefits are observed at microdoses (one-tenth or less of standard diabetes/weight loss doses), with minimal side effects. ### **Clinical Pearls & Practical Considerations** - Patients who are not overweight also benefit, and weight loss is minimal at these low doses. - Appetite suppression and improved food tolerance are common, leading to better quality of life. - The hosts encourage patients to re-challenge foods they previously could not tolerate after starting treatment. - There is curiosity about whether increasing the dose would yield further benefits or more side effects. - The drugs also seem to help with neurological symptoms, joint pain, and possibly even visual disturbances associated with long COVID. ### **Barriers and Logistics** - Insurance typically does not cover these drugs for off-label use, so patients rely on compounding pharmacies. - Recent FDA actions threaten the availability of compounded versions, as compounding is only allowed during official shortages. - Dosing compounded versions can be confusing, as patients must measure their own doses with insulin syringes, unlike the user-friendly commercial pens. ### **Mechanistic and Evolutionary Speculation** - The hosts discuss why GLP-1 receptors are so widespread, theorizing that modern diets and processed foods have disrupted normal physiology, and these drugs may help restore balance. - They propose that GLP-1 RAs could become important in anti-aging/longevity medicine due to their anti-inflammatory effects, similar to drugs like metformin and rapamycin. ### **Research & Future Directions** - The hosts call for more systematic data collection, including biomarkers of inflammation, to better understand and track the drugs’ effects. - They note the lack of robust clinical trial data for these off-label uses and suggest the need for case series and further research. - There is interest in comparing different GLP-1 RAs (semaglutide vs. tirzepatide) and their relative efficacy for inflammation vs. weight loss. ### **Conclusion** - The hosts are enthusiastic about the potential of GLP-1 RAs in treating complex chronic illnesses, especially given the rapid and profound improvements seen in some patients. - They plan to revisit the topic as more experience and data accumulate, and to explore combination therapy with other anti-inflammatory/anti-aging drugs like rapamycin. ## **Key Takeaways** - **GLP-1 receptor agonists, at very low doses, appear to provide significant, rapid benefits for some patients with chronic, complex illnesses (e.g., long COVID, MCAS), beyond their approved uses.** - **Benefits include reduced inflammation, improved mobility, better food tolerance, and improved neurological symptoms.** - **Mechanisms may involve mast cell stabilization, immune modulation, and central nervous system effects.** - **Access is limited by insurance and regulatory issues; compounded versions are threatened by FDA policy changes.** - **There is a need for more systematic research, including biomarker tracking and case series, to validate these observations.** - **GLP-1 RAs may have a future role in longevity and anti-aging medicine due to their anti-inflammatory properties.**

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