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How Do Ozempic and Wegovy Work? Ozempic and Wegovy are synthetic GLP-1 molecules named Semaglutide. Ozempic is approved for type II diabetes mellitus and protection against cardiac events in type II DM patients. Wegovy is approved for weight loss in obese and overweight individuals and for protection against cardiac events in obese and overweight individuals. Let's review the mechanism of action and the side effects of these drugs. If you like this content and want more, click here: https://www.drbeen.com/med-nerd Want to join my uncensored talks? Join me on patreon or substack: Patreon: https://www.patreon.com/mobeensyed?fan_landing=true Substack: https://mobeensyedmd.substack.com/ Want to support this work?: BuyMeACoffee: https://www.buymeacoffee.com/drmobeensyed PayPal: https://paypal.me/mobeensyed?locale.x=en_US #drbeen #koolbeens #Weight_Loss Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. FDA Approves First Treatment to Reduce Risk of Serious Heart Problems Specifically in Adults with Obesity or Overweight | FDA https://www.fda.gov/news-events/press-announcements/fda-approves-first-treatment-reduce-risk-serious-heart-problems-specifically-adults-obesity-or Ozempic for weight loss: Does it work, and what do experts recommend? https://health.ucdavis.edu/blog/cultivating-health/ozempic-for-weight-loss-does-it-work-and-what-do-experts-recommend/2023/07 Semaglutide delays 4-hour gastric emptying in women with polycystic ovary syndrome and obesity - PubMed https://pubmed.ncbi.nlm.nih.gov/36511825/ The metabolic role of vagal afferent innervation | Nature Reviews Gastroenterology & Hepatology https://www.nature.com/articles/s41575-018-0062-1 Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow | American Journal of Physiology-Gastrointestinal and Liver Physiology https://journals.physiology.org/doi/full/10.1152/ajpgi.1998.275.5.G984 Wegovy® Pen Instructions | Wegovy® (semaglutide) Injection 2.4 mg https://www.wegovy.com/taking-wegovy/how-to-use-the-wegovy-pen.html Incretin https://en.wikipedia.org/wiki/Incretin Glucagon-like peptide-1 inhibits gastric emptying via vagal afferent-mediated central mechanisms - PubMed https://pubmed.ncbi.nlm.nih.gov/9357836/ Give the Receptor a Brake: Slowing Gastric Emptying by GLP-1 | Diabetes | American Diabetes Association https://diabetesjournals.org/diabetes/article/63/2/407/34120/Give-the-Receptor-a-Brake-Slowing-Gastric-Emptying GLP-1 Localisation and Proglucagon Gene Expression in Healthy and Diabetic Mouse Ileum - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200298/#:~:text=For%20instance%2C%20proglucagon%20is%20cleaved,13%2C%2016%2C%2027). What Is an L-Cell and How Do We Study the Secretory Mechanisms of the L-Cell? - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218725/ Glucagon-Like Peptide-1 Receptor Agonists for Chronic Weight Management - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533252/ Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow | American Journal of Physiology-Gastrointestinal and Liver Physiology https://journals.physiology.org/doi/full/10.1152/ajpgi.1998.275.5.G984 Why Ozempic Causes Diarrhea and How to Manage Your Symptoms - GoodRx https://www.goodrx.com/ozempic/diarrhea Wegovy (Semaglutide): Uses, Side Effects & Weight Loss https://www.drugwatch.com/drugs/wegovy/#:~:text=Wegovy%20carries%20a%20black%20box,same%20effects%20occur%20in%20humans. Risk of Gastrointestinal Adverse Events Associated With Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss | Gastroenterology | JAMA | JAMA Network https://jamanetwork.com/journals/jama/fullarticle/2810542 The metabolic role of vagal afferent innervation | Nature Reviews Gastroenterology & Hepatology https://www.nature.com/articles/s41575-018-0062-1 What Is an L-Cell and How Do We Study the Secretory Mechanisms of the L-Cell? - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218725/ Enteroendocrine cell - Wikipedia https://en.wikipedia.org/wiki/Enteroendocrine_cell#:~:text=in%20the%20duodenum.-,L%20cell,in%20the%20duodenum%20and%20jejunum. What is ilial brake? inslag.indd https://scholarlypublications.universiteitleiden.nl/access/item%3A2956466/view Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483000/#:~:text=Distinct%20neuronal%20cell%20populations%2C%20particularly,glucose%20metabolism%20and%20energy%20expenditure.

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† On average, Medi-Weightloss Clinics® patients lose 7 pounds the first week and 2 to 3 pounds each week thereafter for the first month. Rapid weight loss may be associated with certain medical conditions and should only be considered by those who are medically appropriate.

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Semaglutide is a medication that has gained popularity in recent years for its effectiveness in helping individuals achieve weight loss. One of the most common goals for individuals who are prescribed semaglutide is to achieve an average weekly weight loss. In this article, we will explore what individuals can expect when aiming for average weekly weight loss on semaglutide and provide helpful tips to reach their weight loss goals.

Understanding Semaglutide and Average Weekly Weight Loss

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by slowing down the digestion process, leading to increased feelings of fullness and reduced appetite. This can result in decreased food intake and ultimately, weight loss. Studies have shown that individuals who take semaglutide along with making healthy lifestyle changes, such as following a balanced diet and exercising regularly, can achieve significant weight loss.

When aiming for average weekly weight loss on semaglutide, it is important to set realistic goals. The average weight loss typically ranges from 1-2 pounds per week. While some individuals may experience greater weight loss in the beginning, it is important to focus on long-term, sustainable weight loss rather than quick fixes.

It is also important to remember that weight loss results may vary from person to person. Factors such as age, gender, metabolism, and starting weight can all play a role in how quickly or slowly an individual loses weight on semaglutide. It is important to be patient and consistent with your efforts, as sustainable weight loss takes time.

Developing Healthy Habits for Success

One key factor in achieving average weekly weight loss on semaglutide is developing healthy habits that support your weight loss goals. This includes following a balanced diet that is rich in fruits, vegetables, lean proteins, and whole grains. It is also important to stay hydrated and limit your intake of sugary drinks and high-calorie foods.

In addition to following a healthy diet, regular physical activity is essential for weight loss success. Aim to incorporate at least 30 minutes of moderate exercise into your daily routine, such as brisk walking, cycling, or swimming. Find activities that you enjoy and make them a priority in your schedule.

It is also important to prioritize self-care and stress management when trying to achieve average weekly weight loss on semaglutide. Stress can hinder weight loss progress by increasing cravings and disrupting sleep. Practice relaxation techniques such as deep breathing, meditation, or yoga to help reduce stress levels and support your weight loss journey.

Monitoring Progress and Making Adjustments

Tracking your progress is key to achieving average weekly weight loss on semaglutide. Keep a food journal to monitor your daily intake and make note of any patterns or triggers that may be hindering your weight loss progress. Additionally, weigh yourself regularly to track your weight loss and celebrate your successes along the way.





If you find that you are not achieving the desired weight loss results, it may be necessary to make adjustments to your diet and exercise routine. Consult with your healthcare provider or a registered dietitian to create a personalized plan that meets your individual needs and supports your weight loss goals. Remember, consistency is key, and small changes over time can lead to big results.

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In conclusion, achieving average weekly weight loss on semaglutide is possible with dedication, patience, and a holistic approach to weight loss. By understanding how semaglutide works, developing healthy habits, and monitoring your progress, you can reach your weight loss goals and improve your overall health and well-being.

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