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Weight loss drugs have become an increasingly popular, but controversial, way of quickly shedding extra pounds over the past few years. Part of that controversy deals with the side effects caused by some of the more well-known medications like Ozempic and Mounjaro. According to the Obesity Medicine Association (OMA), researchers are continually analyzing the pros and cons of these drugs. Here are some side effects of the eight FDA-approved weight loss drugs: Ozempic and Wegovy Ozempic and Wegovy are the brand names of a drug known as semaglutide, a medication that, according to Harvard Health, has been prescribed for about two decades to treat Type 2 diabetes. Ozempic has become controversial over the past few years as overweight and obese patients have sought it out for weight loss, creating a shortage of the drug for those using it to control their diabetes. Wegovy is the brand name for a form of semaglutide that has since been approved for weight loss. Semaglutide, which mimics a natural hormone called GLP-1, helps regulate blood sugar while slowing down the emptying of the stomach and signaling satiety or fullness to the brain. The OMA reports that the most common complaint among patients using semaglutide is gastrointestinal issues like nausea. Other side effects include fatigue, dizziness, headache, bloating, belching and heartburn.An American Medical Association study has also found that GLP-1 agonists are associated with an increased risk of pancreatitis, bowel obstruction, and gastroparesis. While headlines have warned about an increase in suicidal ideation with semaglutide, a January 2024 study in Nature Medicine suggested “a 49% to 73% lower risk of first-time or recurring suicidal ideations” compared with other obesity medications. Mounjaro and Zepbound Mounjaro and Zepbound are drugs known as tirzepatide. Mounjaro was approved in 2017 to treat Type 2 diabetes, while Zepbound was approved in more recent years to treat obesity. Like semaglutide, tirzepatide is a GLP-1 agonist that increases a person’s feeling of fullness and helps them maintain a weight loss diet. It causes common mild symptoms like nausea, constipation, diarrhea and bloating, but the OMA reports more serious side effects like kidney problems up to and including kidney failure, gallbladder symptoms, pancreatitis and hypoglycemia. Manufacturer Eli Lilly warns, however, that Tirzepatide may cause thyroid tumors or thyroid cancer. Patients should monitor themselves for symptoms like neck swelling, hoarseness, problems swallowing and shortness of breath. Contrave Contrave is the brand name for a medication that combines two drugs, bupropion and naltrexone. Bupropion, which is marketed under the brand name Wellbutrin, is an antidepressant that is also known to reduce a person’s appetite. Naltrexone, commonly sold under the brand names Revia and Vivitrol, is a medication used to treat drug and alcohol addiction. According to Drugs.com, naltrexone works by blocking the euphoric, intoxicated feeling of alcohol and opioids. It also helps reduce the cravings for the substances. The OMA reports that patients should not be prescribed Contrave if they suffer from a seizure disorder or if they take opioids for chronic pain. The most common side effects of the drug are nausea, vomiting, constipation, diarrhea, headache, dizziness, dry mouth and insomnia. Saxenda Saxenda is a medication containing liraglutide, a drug that mimics a person’s natural hormones affecting hunger, digestion and feelings of fullness. It was approved by the FDA in 2017 to treat obesity in people 12 and older. The most common side effects of liraglutide are nausea, vomiting, constipation, diarrhea, headache, fatigue, dyspepsia, dizziness and abdominal pain. It can also cause increased heart rate, increased lipase, which is a pancreatic enzyme, and decreased kidney function. Qsymia Qsymia is a medication that combines the drugs phentermine and topiramate. According to the OMA, phentermine has been around since 1959, making it the oldest and most widely used weight loss medication. The drug, which works in the brain as an appetite suppressant, is a stimulant similar to amphetamines and can be abused. It should not be used by patients who have suffered a stroke or who have heart disease, glaucoma or hyperthyroidism. The side effects of phentermine can be serious, including fast or irregular heart rate, headache, overstimulation, high blood pressure and tremors. It can also interact with several other drugs, including MAO inhibitors, alcohol, adrenergic neuron blockers and some anesthetic agents. When phentermine is combined with topiramate, an anticonvulsant, its effect on hunger is magnified. The side effects of the two drugs combined include dizziness, abnormal sensations, altered taste, insomnia, constipation and dry mouth. Topiramate also carries a risk of birth defects, so it should not be taken during pregnancy.

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영국 보건당국이 위고비, 오젬픽, 젭바운드 등 GLP-1 계열 비만치료제 투약 후 급성 췌장염 발병 사례가 잇따르자 조사에 나섰다. 관련 보고는 400건에 육박하며, 절반 가까이가 티르제파티드 계열이었다. 췌장염으로 인한 사망 사례도 보고됐지만, 인과관계는 아직 확인되지 않았다. 당국은 약물 부작용에 취약한 유전적 요인을 파악하기 위해 환자들의 자발적 신고를 기반으로 유전체 연구도 병행할 계획이다.Vision Loss Linked To Popular Weight Loss Drugs Experts Warn

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The media and many "experts" make it seem like the only way to lose weight these days is with the help of GLP-1 drugs—but is the *really* the case? Mike and Jordan give their thoughts on this belief and discuss what ACTUALLY matters when it comes to weight loss and your goals. This clip is from Episode #182 of the podcast. To catch the full episode, head to https://youtu.be/wSdckNwHMwA If you found this helpful, we would sincerely appreciate it if you gave us a thumbs up and subscribed! If you'd like to join us in The Online Fitness Business Mentorship, you can grab your seat at https://www.fitnessbusinessmentorship.com Follow the show on social: Instagram - https://www.instagram.com/personaltrainerpodcast TikTok - https://www.tiktok.com/@personaltrainerpodcast Find us on Instagram: https://www.instagram.com/syattfitness https://www.instagram.com/mikevacanti Check out our new book 'Eat It!' at https://www.eatit-book.com If you have any questions you'd like to have answered on the show, send us an email at [email protected] Join our email list & get our FREE '30 Ways To Build A Successful Online Coaching Business' manual: https://bit.ly/30O2l6p ---- Post-Production by: David Margittai | In Post Media Website: https://www.inpostmedia.com Email: [email protected] © 2024 Michael Vacanti & Jordan Syatt

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The Rise of Eli Lilly’s Weight Loss Drug

In recent years, weight loss has become a focal point for many people, especially in the context of celebrity culture. As many public figures flaunt their toned bodies on social media platforms and red-carpet events, the quest for an effective weight loss solution has intensified. One of the most talked-about responses to this demand has come from Eli Lilly, a major pharmaceutical company that provides weight loss medications that have recently captured the limelight. The drug, known under the generic name semaglutide, which is marketed under different brand names, promises to transform the lives of those who struggle with obesity while also capturing the fascination of those seeking quick fixes to achieve their desired body goals.

The increasing prevalence of obesity has triggered a significant public health crisis, with millions struggling to shed excess weight and improve their overall well-being. Traditional weight loss methods, such as diet and exercise, have often been met with frustration and limited success. This is where pharmaceuticals like Eli Lilly’s semaglutide come into play, offering a new avenue for individuals seeking assistance in their weight loss journey. Advertised as a game changer, the drug has gained immense popularity not only among average consumers but also among celebrities, who allegedly attribute their successful transformations to its efficacy.

While the endorsements from prominent figures certainly help elevate the profile of the drug, it is crucial to explore the science behind it and the physiological mechanisms that contribute to its effectiveness. Unlike generic weight loss pills that simply suppress appetite, Eli Lilly’s drug mimics the action of glucagon-like peptide-1 (GLP-1), a hormone that helps regulate food intake and insulin secretion. By understanding how this drug functions, we can appreciate why it has garnered attention and interest, particularly in the celebrity world. In this article, we will delve deeper into various aspects of Eli Lilly’s weight loss drug, examining its development, impact, and the secrets behind celebrity success stories that are intertwined with its use.

The Science of Semaglutide

At the core of Eli Lilly’s weight loss drug is semaglutide, a synthetic version of a naturally occurring hormone in the body. GLP-1 is crucial in regulating appetite, insulin secretion, and glucose metabolism. Semaglutide works by binding to GLP-1 receptors in the brain, leading to reduced appetite and increased feelings of fullness after meals. This action influences the central nervous system, giving users less desire to eat and ultimately helping them consume fewer calories. By mimicking the effects of natural GLP-1, semaglutide offers a biological solution to weight loss that goes beyond mere willpower.

Clinical trials have demonstrated that patients using semaglutide can lose substantial amounts of weight compared to those on a placebo. The results from these studies have shown that patients can lose an average of 15-20% of their body weight over the course of several months. This is significant, especially compared to traditional weight loss methods, which often yield far lower results. The fast and noticeable outcomes associated with semaglutide are factors that attract individuals who may have become disheartened by their previous weight loss endeavors.

However, it is essential to highlight that semaglutide is not a magic pill. While it provides assistance in managing weight, lifestyle changes such as diet and exercise remain crucial for long-term success. Many users experience a decline in weight during the medication period but must maintain healthier habits post-treatment to avoid regaining weight. Understanding that semaglutide functions as a companion to lifestyle adjustments rather than a standalone solution is vital for anyone considering this medication as part of their weight loss journey.

Celebrities and Their Transformation Journeys

The influence of celebrity culture on weight loss is undeniable, with many stars attributing their stunning transformations to lifestyle changes made possible by the use of medications like semaglutide. For public figures, maintaining an idealized image can be a relentless pursuit. As they face amplified scrutiny from fans and media, the pressure to achieve a perfect appearance can drive them towards modern weight loss solutions. Celebrities have utilized social media platforms to showcase their fitness journeys, creating narratives that often highlight the role of semaglutide in their transformations.

Stars such as Rebel Wilson and mindfully promote their experiences with this drug, thereby helping to destigmatize the use of pharmaceuticals for weight loss. By sharing their stories, they not only provide inspiration to their followers but also contribute to the normalization of discussing weight management openly. This transparency fosters a more profound understanding of the challenges associated with weight loss and encourages others to seek solutions that can include medical interventions.

However, it is essential to approach these narratives with a critical mindset. While celebrity endorsements can inspire action, they may also oversimplify the complexities surrounding weight loss. Celebrities often have access to personal trainers, nutritionists, and resources that the average person may not possess. Therefore, while they share their weight loss drugs journey, individuals must remember that results can vary significantly based on diverse factors such as metabolism, genetics, and overall lifestyle choices.

Medical Perspectives on Weight Loss Drugs

From a medical standpoint, weight loss medications like semaglutide have generated considerable discussion and debate within the healthcare community. Doctors and nutritionists recognize the growing prevalence of obesity and the associated health problems, such as diabetes, heart disease, and certain cancers. As traditional methods often fall short, pharmaceutical companies have become serious players in the weight management arena, providing scientifically backed medications that can help patients achieve sustainable change.

While semaglutide has proven effective for many, healthcare professionals acknowledge that it may not be suitable for everyone. Individuals with a history of certain medical conditions, such as thyroid cancer, pancreatitis, or specific gastrointestinal diseases, may face increased risks when using the drug. Before prescribing semaglutide, it is crucial for medical practitioners to conduct thorough evaluations of each patient’s medical history, current health status, and lifestyle before recommending weight loss medication as part of a comprehensive weight management plan.

In addition to safety concerns, there remain ongoing discussions about the long-term effects of using such drugs. While short-term results are promising, the long-term sustainability of weight loss with semaglutide use requires further study. Experts emphasize the importance of combining the use of medications with lifestyle interventions to promote the best outcomes for individuals seeking to improve their health and physical appearance.

The Future of Weight Management

The evolution of weight management solutions signals a significant shift in how society views obesity and its treatment. As pharmaceutical options like semaglutide become more widely accepted, discussions surrounding obesity are becoming increasingly nuanced. No longer is there a singular focus on diet and exercise alone; instead, a multi-faceted approach that encompasses medical interventions is emerging. This evolution in understanding can foster a more comprehensive dialogue about health and wellness, fostering a culture of acceptance around using medication for weight loss.

Future developments in weight management may also include potential advancements in pharmaceutical research. Scientists are exploring different compounds that may enhance the effectiveness of existing medications or target new physiological pathways involved in appetite regulation and metabolism. As innovative treatments arise, individuals struggling with weight concerns might find new tools to aid their journey, combined with lifestyle changes to yield optimal results.

Moreover, public perceptions on obesity continue to shift. As high-profile endorsements of drugs like semaglutide spread, there’s an opportunity to challenge societal stigmas around weight. By recognizing weight loss as a complex issue requiring diverse solutions, society can promote a more inclusive and supportive environment for those on their weight loss journeys. The hope is that ongoing conversations about obesity and its treatment can lead to better outcomes for those seeking to improve their health and well-being.

Considering Semaglutide: Common Questions Answered

With the growing interest in semaglutide, many potential users have questions about its usage, effectiveness, and overall safety. One common inquiry revolves around how semaglutide works in the body. As previously discussed, semaglutide mimics the GLP-1 hormone, which influences hunger and food intake. By reducing appetite and enhancing feelings of fullness, individuals can experience significant weight loss, especially when paired with dietary changes and physical activity.

Another frequently asked question is the duration of treatment. While some patients see results within weeks, discontinuation of semaglutide can lead to weight regain if lifestyle modifications are not maintained. Therefore, it is vital for users to integrate healthier practices during their treatment period. Consulting healthcare professionals can help in developing a balanced approach that promotes long-term weight management.

<pSafety concerns are also paramount for potential users. Users may experience side effects such as nausea, vomiting, and diarrhea, especially during the initial stages of treatment. Close monitoring by medical professionals can help manage these side effects effectively. Additionally, it is essential for individuals to inform their doctors about any pre-existing conditions that may influence their suitability for using semaglutide. This holistic approach ensures that those seeking weight loss assistance receive the best possible guidance tailored to their unique circumstances.

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